2022-11-16Zeitschriftenartikel
SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression
Niemeyer, Daniela; Stenzel, Saskia; Veith, Talitha; Schroeder, Simon; Friedmann, Kirstin; Weege, Friederike; Trimpert, Jakob; Heinze, Julian; Richter, Anja; Jansen, Jenny; Emanuel, Jackson; Kazmierski, Julia; Pott, Fabian; Jeworowski, Lara M.; Olmer, Ruth; Jaboreck, Mark-Christian; Tenner, Beate; Papies, Jan; Walper, Felix; Schmidt, Marie L.; Heinemann, Nicolas; Möncke-Buchner, Elisabeth; Baumgardt, Morris; Hoffmann, Karen; Widera, Marek; Thao, Tran Thi Nhu; Balázs, Anita; Schulze, Jessica; Mache, Christin; Jones, Terry Carleton; Morkel, Markus; Ciesek, Sandra; Hanitsch, Leif G.; Mall, Markus A.; Hocke, Andreas C.; Thiel, Volker; Osterrieder, Klaus; Wolff, Thorsten; Martin, Ulrich; Corman, Victor M.; Müller, Marcel A.; Goffinet, Christine; Drosten, Christian
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible, infectious, and pathogenic than previous variants. ...
