Browsing Artikel in Fachzeitschriften by Author "Saenger, Sandra"

Now showing items 1-2 of 2

2018-07-19Zeitschriftenartikel

A novel European H5N8 influenza A virus has increased virulence in ducks but low zoonotic potential

Grund, Christian; Hoffmann, Donata; Ulrich, Reiner; Naguib, Mahmoud; Schinköthe, Jan; Hoffmann, Bernd; Harder, Timm; Saenger, Sandra; Zscheppang, Katja; Tönnies, Mario; Hippenstiel, Stefan; Hocke, Andreas; Wolff, Thorsten; Beer, Martin

We investigated in a unique setup of animal models and a human lung explant culture biological properties, including zoonotic potential, of a representative 2016 highly pathogenic avian influenza virus (HPAIV) H5N8, clade ...
2018-06-26Zeitschriftenartikel

The RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling

Núñez, Rocío Daviña; Budt, Matthias; Saenger, Sandra; Paki, Katharina; Arnold, Ulrike; Sadewasser, Anne; Wolff, Thorsten

Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of influenza virus RNA that induces the expression of antiviral type I ...