2012-09-27Zeitschriftenartikel
Confidence-based Somatic Mutation Evaluation and Prioritization
Löwer, Martin; Renard, Bernhard Y.; Graaf, Jos de; Wagner, Meike; Paret, Claudia; Kneip, Christoph; Türeci, Özlem; Diken, Mustafa; Britten, Cedrik; Kreiter, Sebastian; Koslowski, Michael; Castle, John C.; Sahin, Ugur
Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation ...
