Auflistung Artikel in Fachzeitschriften nach Autor "von Berg, Laura"

Anzeige der Publikationen 1-4 von 4

2018-05-02Zeitschriftenartikel

A lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency

Stern, Daniel; Weisemann, Jasmin; Le Blanc, Alexander; von Berg, Laura; Mahrhold, Stefan; Piesker, Janett; Laue, Michael; Luppa, Peter B.; Dorner, Martin B.; Dorner, Brigitte G.; Rummel, Andreas

The exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of synaptic vesicle proteins embedded in the presynaptic membrane. ...
2019-04-02Zeitschriftenartikel

Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology

von Berg, Laura; Stern, Daniel; Pauly, Diana; Mahrhold, Stefan; Weisemann, Jasmin; Jentsch, Lisa; Hansbauer, Eva-Maria; Müller, Christian; Avondet, Marc A.; Rummel, Andreas; Dorner, Martin B.; Dorner, Brigitte G.

Botulinum neurotoxins (BoNTs) are the most potent toxins known and cause the life threatening disease botulism. Sensitive and broad detection is extremely challenging due to the toxins’ high potency and molecular heterogeneity ...
2019-10-11Zeitschriftenartikel

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A–F Employing Taguchi Design-of-Experiments

von Berg, Laura; Stern, Daniel; Weisemann, Jasmin; Rummel, Andreas; Dorner, Martin Bernhard; Dorner, Brigitte Gertrud

The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor) attachment protein receptor (SNARE) proteins by ...
2018-06-26Zeitschriftenartikel

Replacing the mouse bioassay for diagnostics and potency testing of botulinum neurotoxins – progress and challenges

Stern, Daniel; von Berg, Laura; Skiba, Martin; Dorner, Martin B.; Dorner, Brigitte G.

Botulinum neurotoxins (BoNTs) are the most potent toxins known and the causative agents of the rare but potentially life-threatening disease botulism. The elaborate mode of action of BoNTs at the molecular level, their ...