Auflistung Artikel in Fachzeitschriften nach Autor "Hippenstiel, Stefan"

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2018-07-19Zeitschriftenartikel

A novel European H5N8 influenza A virus has increased virulence in ducks but low zoonotic potential

Grund, Christian; Hoffmann, Donata; Ulrich, Reiner; Naguib, Mahmoud; Schinköthe, Jan; Hoffmann, Bernd; Harder, Timm; Saenger, Sandra; Zscheppang, Katja; Tönnies, Mario; Hippenstiel, Stefan; Hocke, Andreas; Wolff, Thorsten; Beer, Martin

We investigated in a unique setup of animal models and a human lung explant culture biological properties, including zoonotic potential, of a representative 2016 highly pathogenic avian influenza virus (HPAIV) H5N8, clade ...
2021-10-08Zeitschriftenartikel

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

Loyal, Lucie; Braun, Julian; Henze, Larissa; Kruse, Beate; Dingeldey, Manuela; Reimer, Ulf; Kern, Florian; Schwarz, Tatjana; Mangold, Maike; Unger, Clara; Dörfler, Friederike; Kadler, Shirin; Rosowski, Jennifer; Gürcan, Kübrah; Uyar-Aydin, Zehra; Frentsch, Marco; Kurth, Florian; Schnatbbaum, Karsten; Eckey, Maren; Hippenstiel, Stefan; Hocke, Andreas; Müller, Marcel A.; Sawitzki, Birgit; Miltenyi, Stefan; Paul, Friedemann; Mall, Marcus A.; Wenschuh, Holger; Voigt, Sebastian; Drosten, Christian; Lauster, Roland; Lachman, Nils; Sander, Leif-Erik; Corman, Victor M.; Röhmel, Jobst; Meyer-Arndt, Lil; Thiel, Andreas; Giesecke-Thiel, Claudia

INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection to respiratory failure. Severe disease courses are primarily associated with advanced age, immune dysfunctions, and comorbidities. ...
2021-09-07Zeitschriftenartikel

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

Schroeder, Simon; Christin, Mache; Kleine-Weber, Hannah; Corman, Victor M.; Muth, Doreen; Richter, Anja; Fatykhova, Diana; Memish, Ziad A.; Stanifer, Megan L.; Boulant, Steeve; Gultom, Mitra; Dijkman, Ronald; Eggeling, Stephan; Hocke, Andreas; Hippenstiel, Stefan; Thiel, Volker; Pöhlmann, Stefan; Wolff, Thorsten; Müller, Marcel A.; Drosten, Christian

Middle East respiratory syndrome coronavirus (MERS-CoV) is enzootic in dromedary camels across the Middle East and Africa. Virus-induced pneumonia in humans results from animal contact, with a potential for limited onward ...
2010-07-08Zeitschriftenartikel

Legionella pneumophila induces human beta Defensin-3 in pulmonary cells

Scharf, Stefanie; Vardarova, Kremena; Lang, Friederike; Schmeck, Bernd; Opitz, Bastian; Flieger, Antje; Heuner, Klaus; Hippenstiel, Stefan; Suttorp, Norbert; N'Guessan, Philippe D

Background: Legionella pneumophila is an important causative agent of severe pneumonia in humans. Human alveolar epithelium and macrophages are effective barriers for inhaled microorganisms and actively participate in the ...
2013-10-08Zeitschriftenartikel

The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue

Knepper, Jessica; Schierhorn, Kristina L.; Becher, Anne; Budt, Matthias; Tönnies, Mario; Bauer, Torsten T.; Schneider, Paul; Neudecker, Jens; Rückert, Jens C.; Gruber, Achim D.; Suttorp, Norbert; Schweiger, Brunhilde; Hippenstiel, Stefan; Hocke, Andreas C.; Wolff, Thorsten

A novel influenza A virus (IAV) of the H7N9 subtype has been isolated from severely diseased patients with pneumonia and acute respiratory distress syndrome and, apparently, from healthy poultry in March 2013 in Eastern ...