Artikel in Fachzeitschriften: Neuzugänge
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2022-04-07ZeitschriftenartikelHIV pre-exposure prophylaxis was associated with no impact on sexually transmitted infection prevalence in a high-prevalence population of predominantly men who have sex with men, Germany, 2018 to 2019 Introduction: Despite increased use of pre-exposure prophylaxis (PrEP) in Germany, HIV infection rates are not declining and little is known about how this prevention method affects the prevalence of sexually transmitted ...
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2022-04-24ZeitschriftenartikelImported Pet Reptiles and Their “Blind Passengers”—In-Depth Characterization of 80 Acinetobacter Species Isolates Reptiles are popular pet animals and important food sources, but the trade of this vertebrate class is—besides welfare and conservation—under debate due to zoonotic microbiota. Ninety-two shipments of live reptiles were ...
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2022-03-16ZeitschriftenartikelExclusion of Mucorales Co-Infection in a Patient with Aspergillus flavus Sinusitis by Fluorescence In Situ Hybridization (FISH) Invasive fungal infections are associated with increased mortality in hematological patients. Despite considerable advances in antifungal therapy, the evaluation of suspected treatment failure is a common clinical challenge ...
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2022-04-05ZeitschriftenartikelThe Evolution of Complex Muscle Cell In Vitro Models to Study Pathomechanisms and Drug Development of Neuromuscular Disease Many neuromuscular disease entities possess a significant disease burden and therapeutic options remain limited. Innovative human preclinical models may help to uncover relevant disease mechanisms and enhance the translation ...
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2022-04-02ZeitschriftenartikelParamyxovirus Diversity within One Population of Miniopterus fuliginosus Bats in Sri Lanka Bats are known as typical reservoirs for a number of viruses, including viruses of the family Paramyxoviridae. Representatives of the subfamily Orthoparamyxovirinae are distributed worldwide and can cause mild to fatal ...
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2022-04-07ZeitschriftenartikelHIV, STI and renal function testing frequency and STI history among current users of self-funded HIV pre-exposure prophylaxis, a cross-sectional study, Germany, 2018 and 2019 Introduction: Users of pre-exposure prophylaxis (PrEP) require periodic testing for HIV, sexually transmitted infections (STI) and renal function. Before PrEP was made free of charge through statutory health insurance in ...
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2022-03-28ZeitschriftenartikelShort- and long-range interactions in the HIV-1 5′ UTR regulate genome dimerization and packaging RNA dimerization is the noncovalent association of two human immunodeficiency virus-1 (HIV-1) genomes. It is a conserved step in the HIV-1 life cycle and assumed to be a prerequisite for binding to the viral structural ...
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2022-04-26ZeitschriftenartikelPotential of prevention strategies for the modifiable risk factor type 2 diabetes with relation to the future number of dementia patients in Germany– a multi-state projection through 2040 Background: We assess the impact of prevention strategies regarding type 2 diabetes as a modifiable risk factor for dementia and its consequences for the future number of dementia patients in Germany. Methods: We used ...
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2022-03-16ZeitschriftenartikelPhylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load Set-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising ...
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2022-03-31ZeitschriftenartikelRadiation exposure by medical X-ray applications Background: Radioactive material and ionising radiation play a central role in medical diagnostics and therapy. The benefit of ionising radiation is opposed by the risk of irreparable damage of the human organism. This ...
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2022-01-07ZeitschriftenartikelBurden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices Background: Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing ...
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2022-04-11ZeitschriftenartikelIdentifying content to improve risk assessment communications within the Risk Profile: Literature reviews and focus groups with expert and non-expert stakeholders Objective: To improve consumer decision making, the results of risk assessments on food, feed, consumer products or chemicals need to be communicated not only to experts but also to non-expert audiences. The present study ...
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2022-04-07ZeitschriftenartikelSocioeconomic position and self-rated health among female and male adolescents: The role of familial determinants in explaining health inequalities. Results of the German KiGGS study Objective: Although health inequalities in adolescence are well documented, the underlying mechanisms remain unclear. Few studies have examined the role of the family in explaining the association between the family’s ...
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2022-03-31ZeitschriftenartikelVirA+EmiC project: Evaluating real-world effectiveness and sustainability of integrated routine opportunistic hepatitis B and C testing in a large urban emergency department Innovative testing approaches and care pathways are required to meet global hepatitis B virus (HBV) and hepatitis C virus (HCV) elimination goals. Routine blood-borne virus (BBV) testing in emergency departments (EDs) in ...
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2022-04-07ZeitschriftenartikelStructured diabetes self-management education and its association with perceived diabetes knowledge, information, and disease distress: Results of a nationwide population-based study Objective: To evaluate, how participation in structured diabetes self-management education (DSME) programs is associated with perceived level of knowledge about diabetes, information needs, information sources and disease ...
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2022-03-22ZeitschriftenartikelNear Chromosome-Level Genome Assembly and Annotation of Rhodotorula babjevae Strains Reveals High Intraspecific Divergence The genus Rhodotorula includes basidiomycetous oleaginous yeast species. Rhodotorula babjevae can produce compounds of biotechnological interest such as lipids, carotenoids, and biosurfactants from low value substrates ...
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2022-04-06ZeitschriftenartikelZoonotic origin of the human malaria parasite Plasmodium malariae from African apes The human parasite Plasmodium malariae has relatives infecting African apes (Plasmodium rodhaini) and New World monkeys (Plasmodium brasilianum), but its origins remain unknown. Using a novel approach to characterise P. ...
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2019ZeitschriftenartikelInfektionen des Menschen mit Affenpocken Human Monkeypox
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2022-04-14ZeitschriftenartikelN-chlorotaurine is highly active against respiratory viruses including SARS-CoV-2 (COVID-19) in vitro N-chlorotaurine (NCT) a long-lived oxidant generated by leukocytes, can be synthesized chemically and applied topically as an anti-infective to different body sites, including the lung via inhalation. Here, we demonstrate ...
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2022-04-06ZeitschriftenartikelNon-invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture Human respiratory pathogens have repeatedly caused lethal outbreaks in wild great apes across Africa, leading to population declines. Nonetheless, our knowledge of potential genomic changes associated with pathogen ...