Artikel in Fachzeitschriften: Recent submissions
Now showing items 181-200 of 3855
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2022-03-16ZeitschriftenartikelMurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling Gram-positive bacteria are protected by a thick mesh of peptidoglycan (PG) completely engulfing their cells. This PG network is the main component of the bacterial cell wall, it provides rigidity and acts as foundation for ...
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2022-06-10ZeitschriftenartikelAdaptation of Listeria monocytogenes to perturbation of c-di-AMP metabolism underpins its role in osmoadaptation and identifies a fosfomycin uptake system The human pathogen Listeria monocytogenes synthesizes and degrades c-di-AMP using the diadenylate cyclase CdaA and the phosphodiesterases PdeA and PgpH respectively. c-di-AMP is essential because it prevents the uncontrolled ...
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2022-07-07ZeitschriftenartikelRecombinant AcnB, NrdR and RibD of Acinetobacter baumannii and their potential interaction with DNA adenine methyltransferase AamA In the last decades Acinetobacter baumannii developed into an increasingly challenging nosocomial pathogen. A. baumannii ATCC 17978 harbors a DNA-(adenine N6)-methyltransferase termed AamA. Previous studies revealed a low ...
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2022-06-06ZeitschriftenartikelHuman duodenal organoid-derived monolayers serve as a suitable barrier model for duodenal tissue Usually, duodenal barriers are investigated using intestinal cell lines like Caco-2, which in contrast to native tissue are limited in cell-type representation. Organoids can consist of all intestinal cell types and are ...
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2022-09-23ZeitschriftenartikelPhysical Activity Treatment in Adults with Type 2 Diabetes Mellitus per National Treatment Guidelines for Germany: A Telephone-Survey-Based Analysis Physical activity (PA) is effective in the prevention of type 2 diabetes mellitus (T2DM). According to the German national treatment guidelines for T2DM, PA is recommended at all stages of the treatment process. Adults ...
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2022-08-08ZeitschriftenartikelMolecular Epidemiology of Mycobacterium abscessus Isolates Recovered from German Cystic Fibrosis Patients Infections due to Mycobacterium abscessus are a major cause of mortality and morbidity in cystic fibrosis (CF) patients. Furthermore, M. abscessus has been suspected to be involved in person-to-person transmissions. In ...
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2022-08-09ZeitschriftenartikelAnimal Histoplasmosis in Europe: Review of the Literature and Molecular Typing of the Etiological Agents Histoplasmosis has been previously diagnosed in animals from Europe. The aim of this study is to review the literature on these reports, to analyze cases diagnosed at our laboratory (2000–2022) and to improve molecular ...
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2022-12-20ZeitschriftenartikelICTV Virus Taxonomy Profile: Matonaviridae 2022
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2022-12-13ZeitschriftenartikelEvaluation of CHROMagar Acinetobacter and MacConkey media for the recovery of Acinetobacter baumannii from soil samples The opportunistic pathogen Acinetobacter baumannii occupies niches in human and veterinary clinics and other environments. This comparative study was designed to assess the recovery rate of Ac. baumannii from 20 soil samples ...
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2022-05-05ZeitschriftenartikelSupervised learning using routine surveillance data improves outbreak detection of Salmonella and Campylobacter infections in Germany The early detection of infectious disease outbreaks is a crucial task to protect population health. To this end, public health surveillance systems have been established to systematically collect and analyse infectious ...
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2022-11-17ZeitschriftenartikelOutbreak of imported diphtheria with Corynebacterium diphtheriae among migrants arriving in Germany, 2022 From July 2022, cases of imported diphtheria with toxigenic Corynebacterium diphtheriae remarkably increased among migrants arriving in Germany. Up to 30 September 2022, 44 cases have been reported to the national ...
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2022-11-10ZeitschriftenartikelImpact of the COVID-19 pandemic on influenza and respiratory syncytial virus antibody titres in the community: a prospective cohort study in Neustadt, Thuringia, Germany
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2022-10-12ZeitschriftenartikelSexual happiness and satisfaction with sexual safety among German trans men who have sex with men: results from EMIS-2017 Introduction The population of men-who-have-sex-with-men (MSM) includes people who are on the masculine spectrum but were assigned female at birth (AFAB), that is trans MSM. This study aims to identify current circumstances ...
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2022-04-29ZeitschriftenartikelDetermination of respiratory syncytial virus epidemic seasons by using 95% confidence interval of positivity rates, 2011–2021, Germany Based on our national outpatient sentinel surveillance, we have developed a novel approach to determine respiratory syncytial virus (RSV) epidemic seasons in Germany by using RSV positivity rate and its lower limit of 95% ...
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2022-10-27ZeitschriftenartikelSARS-CoV-2 Omicron variant is attenuated for replication in a polarized human lung epithelial cell model SARS-CoV-2 and its emerging variants of concern remain a major threat for global health. Here we introduce an infection model based upon polarized human Alveolar Epithelial Lentivirus immortalized (hAELVi) cells grown at ...
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2022-09-16ZeitschriftenartikelGermany’s fourth COVID-19 wave was mainly driven by the unvaccinated Background While the majority of the German population was fully vaccinated at the time (about 65%), COVID-19 incidence started growing exponentially in October 2021 with about 41% of recorded new symptomatic cases aged ...
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2022-09-09ZeitschriftenartikelBNT162b2 vaccination reduced infections and transmission in a COVID-19 outbreak in a nursing home in Germany, 2021 Background A SARS-CoV-2 outbreak was detected in a nursing home in February 2021 after residents and staff had received two doses of BNT162b2 vaccine in January 2021. Methods Nursing home staff, long-term residents ...
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2022-11-14ZeitschriftenartikelNationally representative results on SARS-CoV-2 seroprevalence and testing in Germany at the end of 2020 Pre-vaccine SARS-CoV-2 seroprevalence data from Germany are scarce outside hotspots, and socioeconomic disparities remained largely unexplored. The nationwide representative RKI-SOEP study (15,122 participants, 18–99 years, ...
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2022-07-09ZeitschriftenartikelTick-borne encephalitis vaccine effectiveness and barriers to vaccination in Germany Tick-borne encephalitis (TBE) vaccination coverage remains low in Germany. Our case–control study (2018–2020) aimed to examine reasons for low vaccine uptake, vaccine effectiveness (VE), and vaccine breakthrough infections ...
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2022-02-09ZeitschriftenartikelPrimary glia cells from bank vole propagate multiple rodent-adapted scrapie prions Since the beginning prion research has been largely dependent on animal models for deciphering the disease, drug development or prion detection and quantification. Thereby, ethical as well as cost and labour-saving aspects ...