Artikel in Fachzeitschriften: Neuzugänge
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2021-12-25ZeitschriftenartikelGlycopeptide resistance in Enterococcus spp. and coagulase-negative staphylococci from hospitalised patients in Germany: occurrence, characteristics and dalbavancin susceptibility Objectives: The aim of this study was to evaluate the occurrence of glycopeptide resistance in enterococci and coagulase-negative staphylococci (CoNS) and to determine the susceptibilities of the identified glycopeptide-resistant ...
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2022-01-29ZeitschriftenartikelPhenotypic Diversity of Cryptococcus neoformans var. neoformans Clinical Isolates from Localized and Disseminated Infections Cryptococcus neoformans var. neoformans is the second most prevalent agent of cryptococcosis in central Europe. Infections mostly present with localized skin and disseminated infections. Previous studies did not find these ...
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2022-01-20ZeitschriftenartikelRNA reference materials with defined viral RNA loads of SARS-CoV-2—A useful tool towards a better PCR assay harmonization SARS-CoV-2, the cause of COVID-19, requires reliable diagnostic methods to track the circulation of this virus. Following the development of RT-qPCR methods to meet this diagnostic need in January 2020, it became clear ...
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2022-02-02ZeitschriftenartikelAdvanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients The awareness of hepatitis E virus (HEV) increased significantly in the last decade due to its unexpectedly high prevalence in high-income countries. There, infections with HEV-genotype 3 (HEV-3) are predominant which can ...
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2022-01-22ZeitschriftenartikelThe role of personality traits and social support in relations of health-related behaviours and depressive symptoms Background: Previous evidence has suggested that physically inactive individuals and extensive media users are at high risk for experiencing depressive symptoms. We examined personality traits and perceived social support ...
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2022-02-02ZeitschriftenartikelConstruction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals. Despite causing a life-threatening disease, BoNT is a ...
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2021-11-12ZeitschriftenartikelThe Effect of Socioeconomic Factors and Indoor Residual Spraying on Malaria in Mangaluru, India: A Case-Control Study India faces 0.5 million malaria cases annually, including half of all Plasmodium vivax malaria cases worldwide. This case–control study assessed socioeconomic determinants of urban malaria in coastal Mangaluru, Karnataka, ...
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2021-12-21ZeitschriftenartikelHuman Borna disease virus 1 (BoDV-1) encephalitis cases in the north and east of Germany In 2021, three encephalitis cases due to the Borna disease virus 1 (BoDV-1) were diagnosed in the north and east of Germany. The patients were from the states of Thuringia, Saxony-Anhalt, and Lower Saxony. All were residents ...
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2021-11-02ZeitschriftenartikelMachine Learning for Health: Algorithm Auditing & Quality Control Developers proposing new machine learning for health (ML4H) tools often pledge to match or even surpass the performance of existing tools, yet the reality is usually more complicated. Reliable deployment of ML4H to the ...
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2021-10-14ZeitschriftenartikelHeatwave-associated Vibrio infections in Germany, 2018 and 2019 Background: Vibrio spp. are aquatic bacteria that prefer warm seawater with moderate salinity. In humans, they can cause gastroenteritis, wound infections, and ear infections. During the summers of 2018 and 2019, unprecedented ...
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2021-11-02ZeitschriftenartikelSdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase Legionella pneumophila grows intracellularly within a replication vacuole via action of Icm/Dot-secreted proteins. One such protein, SdhA, maintains the integrity of the vacuolar membrane, thereby preventing cytoplasmic ...
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2021-11-21ZeitschriftenartikelRe-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021 We report a rapid increase in enterovirus D68 (EV-D68) infections, with 139 cases reported from eight European countries between 31 July and 14 October 2021. This upsurge is in line with the seasonality of EV-D68 and was ...
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2021-11-11ZeitschriftenartikelViral Myocarditis—From Pathophysiology to Treatment The diagnosis of acute and chronic myocarditis remains a challenge for clinicians. Characterization of this disease has been hampered by its diverse etiologies and heterogeneous clinical presentations. Most cases of ...
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2021-07-27ZeitschriftenartikelDetermination of a Tentative Epidemiological Cut-Off Value (ECOFF) for Dalbavancin and Enterococcus faecium Dalbavancin is a lipoglycopeptide antibiotic that shows potent activity against Gram-positive bacteria. It circumvents vanB-type glycopeptide resistance mechanisms; however, data on the in vitro activity of dalbavancin for ...
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2021-07-30ZeitschriftenartikelRapid and Robust Continuous Purification of High-Titer Hepatitis B Virus for In Vitro and In Vivo Applications Available treatments for hepatitis B can control the virus but are rarely curative. This led to a global initiative to design new curative therapies for the 257 million patients affected. Discovery and development of these ...
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2021-07-20ZeitschriftenartikelThe effect of influenza and pneumococcal vaccination in the elderly on health service utilisation and costs: a claims data-based cohort study Background: To date, cost-effectiveness of influenza and pneumococcal vaccinations was assumed in several health economic modelling studies, but confirmation by real-world data is sparse. The aim of this study is to assess ...
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2021-08-03ZeitschriftenartikelPrevalence and determinants of inappropriate antibiotic dispensing at private drug retail outlets in urban and rural areas of Indonesia: a mixed methods study Introduction: The aim of this mixed-method study was to determine the extent and determinants of inappropriate dispensing of antibiotics by licensed private drug retail outlets in Indonesia. Methods: Standardised patients ...
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2021-07-07ZeitschriftenartikelSelbstwahrgenommene Mundgesundheit und assoziierte Faktoren bei Erwachsenen in Deutschland. Ergebnisse aus GEDA 2019/2020-EHIS Hintergrund und Ziel der Arbeit: Informationen zur Mundgesundheit der Bevölkerung sind wichtig für die Einschätzung von (vermeidbarer) Krankheitslast, für die Einschätzung und Planung von Gesundheitsressourcen und -kosten ...
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2021-07-01Zeitschriftenartikel“This Graft-vs.-Host Disease Determines My Life. That's It.”—A Qualitative Analysis of the Experiences and Needs of Allogenic Hematopoietic Stem Cells Transplantation Survivors in Germany Background: Allogeneic hematopoietic stem cell transplantation (alloHSCT) is the only curative treatment modality for many patients affected by hematologic malignancies. However, it can cause debilitating long-term effects. ...
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2021-07-16ZeitschriftenartikelNicht-Cholera-Vibrionen – derzeit noch seltene, aber wachsende Infektionsgefahr in Nord- und Ostsee Hintergrund: Nicht-Cholera-Vibrionen nehmen im Rahmen des Klimawandels eine zunehmende Bedeutung als humane Pathogene ein, da die Prävalenz dieser Erreger im Meereswasser entscheidend von der Wassertemperatur abhängt. In ...