Artikel in Fachzeitschriften: Neuzugänge
Anzeige der Publikationen 661-680 von 4093
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2021-07-22ZeitschriftenartikelSports activity patterns and cardio-metabolic health over time among adults in Germany: Results of a nationwide 12-year follow-up study Background Physical activity is favorable for health, and vigorous sports activity is particularly beneficial. This study investigates the association between changes in sports participation patterns over time and ...
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2021-08-25ZeitschriftenartikelCoordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii Intracellular parasites of the phylum Apicomplexa are dependent on the scavenging of essential amino acids from their hosts. We previously identified a large family of apicomplexan-specific plasma membrane-localized amino ...
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2021-04-01ZeitschriftenartikelGenomic Diversity and Virulence Potential of ESBL- and AmpC-β-Lactamase-Producing Escherichia coli Strains From Healthy Food Animals Across Europe The role of livestock animals as a putative source of ESBL/pAmpC E. coli for humans is a central issue of research. In a large-scale pan-European surveillance, 2,993 commensal Escherichia spp. isolates were recovered from ...
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2021-12-14ZeitschriftenartikelTranscriptional Active Parvovirus B19 Infection Predicts Adverse Long-Term Outcome in Patients with Non-Ischemic Cardiomyopathy Parvovirus B19 (B19V) is the predominant cardiotropic virus currently found in endomyocardial biopsies (EMBs). However, direct evidence showing a causal relationship between B19V and progression of inflammatory cardiomyopathy ...
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2021-05ZeitschriftenartikelActive Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018–2020 Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1). We conducted a prospective study of bornavirus etiology of ...
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2021-04-30ZeitschriftenartikelProphylaxis and treatment of influenza: options, antiviral susceptibility, and existing recommendations Influenza viruses of types A and B attack 5–10% of adults and 20–30% of children, thereby causing millions of acute respiratory infections in Germany annually. A significant number of these infections are associated with ...
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2021-12-14ZeitschriftenartikelInsights into the direct anti-influenza virus mode of action of Rhodiola rosea Background: The anti-influenza A virus activities and contents of previously isolated most active flavonoids (rhodiosin and tricin) from a standardized hydro-ethanolic R. rosea root and rhizome extract (SHR-5®), did not ...
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2021-08-04ZeitschriftenartikelGene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients Group-aggregated responses to tuberculosis (TB) have been well characterized on a molecular level. However, human beings differ and individual responses to infection vary. We have combined a novel approach to individual ...
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2020-11-19ZeitschriftenartikelEndogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines Many tumour cells express on their surface proteins of endogenous retroviruses (ERVs) and there are suggestions to use these retroviral antigens as target for anti-tumour vaccines. However, until now there is no convincing ...
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2021-06-22ZeitschriftenartikelStructure of Chimpanzee Gut Microbiomes across Tropical Africa Understanding variation in host-associated microbial communities is important given the relevance of microbiomes to host physiology and health. Using 560 fecal samples collected from wild chimpanzees (Pan troglodytes) ...
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2021-06-24ZeitschriftenartikelA global metagenomic map of urban microbiomes and antimicrobial resistance We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an ...
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2021-11-13ZeitschriftenartikelEvaluation of virulence potential of methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates from a German refugee cohort Background Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) seem to be highly transmissible, often infect otherwise healthy humans and frequently occur in hospital outbreaks. Methods Refugees, ...
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2021-07-08ZeitschriftenartikelEditorial: Pathogenomics of the Genus Brucella and Beyond
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2021-03-21ZeitschriftenartikelThe Spatiotemporal Dynamics and Microevolution Events That Favored the Success of the Highly Clonal Multidrug-Resistant Monophasic Salmonella Typhimurium Circulating in Europe The European epidemic monophasic variant of Salmonella enterica serovar Typhimurium (S. 1,4,[5],12:i:-) characterized by the multi locus sequence type ST34 and the antimicrobial resistance ASSuT profile has become one of ...
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2021-11-11ZeitschriftenartikelHospital-acquired infections caused by enterococci: a systematic review and meta-analysis, WHO European Region, 1 January 2010 to 4 February 2020 Background Hospital-acquired infections (HAI) caused by Enterococcus spp., especially vancomycin-resistant Enterococcusspp. (VRE), are of rising concern. Aim We summarised data on incidence, mortality and proportion ...
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2021-12-06ZeitschriftenartikelImpact of the COVID-19 pandemic on ongoing health research: an ad hoc survey among investigators in Germany Objectives To gain insights into the impact of the COVID-19 pandemic on ongoing health research projects, using projects from a selected funding programme in Germany as an example. Design Online survey and validation ...
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2021-07-28ZeitschriftenartikelporeCov-An Easy to Use, Fast, and Robust Workflow for SARS-CoV-2 Genome Reconstruction via Nanopore Sequencing In response to the SARS-CoV-2 pandemic, a highly increased sequencing effort has been established worldwide to track and trace ongoing viral evolution. Technologies, such as nanopore sequencing via the ARTIC protocol are ...
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2021-10-14ZeitschriftenartikelHealthcare-associated foodborne outbreaks in high-income countries: a literature review and surveillance study, 16 OECD countries, 2001 to 2019 Background Healthcare-associated foodborne outbreaks (HA-FBO) may have severe consequences, especially in vulnerable groups. Aim The aim was to describe the current state of HA-FBO and propose public health ...
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2021-08-06ZeitschriftenartikelEmpirical evidence to understand the human factor for effective rapid testing against SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapid antigen point-of-care and home tests are available to lay- people. In four cross-sectional mixed-methods data collections con- ducted between December ...
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2021-04-30ZeitschriftenartikelMolecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most ...