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2020-05-30Zeitschriftenartikel DOI: 10.1016/j.mmcr.2020.05.007
Disseminated coccidioidomycosis: Monitoring of serologic markers for treatment response
dc.contributor.authorWilmes, Dunja
dc.contributor.authorSchui, Daniela
dc.contributor.authorHeld, Jürgen
dc.contributor.authorAckermann, Sina
dc.contributor.authorGeipel, Udo
dc.contributor.authorEmrich, Kai
dc.contributor.authorWinkelmann, Ernst-Joachim
dc.contributor.authorRickerts, Volker
dc.date.accessioned2021-02-18T08:04:35Z
dc.date.available2021-02-18T08:04:35Z
dc.date.issued2020-05-30none
dc.identifier.other10.1016/j.mmcr.2020.05.007
dc.identifier.urihttp://edoc.rki.de/176904/7806
dc.description.abstractWe describe a patient with a disseminated coccidioidomycosis. Biomarkers in serum during itraconazole therapy showed a rapid clearing of Coccidioides DNA as detected by PCR. Coccidioides antibody detection by lateral flow assay became negative after one year and decreased from 1:64 to 1:8 in the complement fixation test after two years. The (1 → 3)-ß-D-glucan levels normalised after two years without increase after cessation of antifungal therapy. Biomarkers in serum may guide treatment decisions in disseminated coccidioidomycosis.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY-NC-ND 3.0 DE) Namensnennung - Nicht-kommerziell - Keine Bearbeitung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/de/
dc.subjectCoccidioidomycosiseng
dc.subjectEndemic mycosiseng
dc.subjecttravel Related diseaseseng
dc.subjectOsteomyelitiseng
dc.subjectCoccidioides qPCReng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleDisseminated coccidioidomycosis: Monitoring of serologic markers for treatment responsenone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/7806-3
dc.identifier.doihttps://doi.org/10.1016/j.mmcr.2020.05.007
dc.identifier.doihttp://dx.doi.org/10.25646/8037
dc.type.versionpublishedVersionnone
local.edoc.container-titleMedical Mycology Case Reportsnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.sciencedirect.com/science/article/pii/S2211753920300361none
local.edoc.container-publisher-nameElseviernone
local.edoc.container-volume29none
local.edoc.container-reportyear2020none
local.edoc.container-firstpage25none
local.edoc.container-lastpage28none
local.edoc.rki-departmentInfektionskrankheitennone
dc.description.versionPeer Reviewednone

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