Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010
Brinckmann, Sarah
Costa, Kelly Da
Gils, Marit J. van
Hallengärd, David
Klein, Katja
Madeira, Luisa
Mainetti, Lara
Palma, Paolo
Raue, Katharina
Reinhart, David
Reudelsterz, Marc
Ruffin, Nicolas
Seifried, Janna
Schäfer, Katrein
Sheik-Khalil, Enas
Sköld, Annette
Uchtenhagen, Hannes
Vabret, Nicolas
Ziglio, Serena
Scarlatti, Gabriella
Shattock, Robin
Wahren, Britta
Gotch, Frances
Novel, exciting intervention strategies to prevent infection with HIV have been tested in the past year, and the field is rapidly evolving. EUROPRISE is a network of excellence sponsored by the European Commission and concerned with a wide range of activities including integrated developmental research on HIV vaccines and microbicides from discovery to early clinical trials. A central and timely theme of the network is the development of the unique concept of co-usage of vaccines and microbicides. This review, prepared by the PhD students of the network captures much of the research ongoing between the partners. The network is in its 5th year and involves over 50 institutions from 13 European countries together with 3 industrial partners; GSK, Novartis and Sanofi- Pasteur. EUROPRISE is involved in 31 separate world-wide trials of Vaccines and Microbicides including 6 in African countries (Tanzania, Mozambique, South Africa, Kenya, Malawi, Rwanda), and is directly supporting clinical trials including MABGEL, a gp140-hsp70 conjugate trial and HIVIS, vaccine trials in Europe and Africa.
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