Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Schwarz, Tatjana; Tober-Lau, Pinkus; Hillus, David; Helbig, Elisa T.; Lippert, Lena J.; Thibeault, Charlotte; Koch, Willi; Landgraf, Irmgard; Michel, Janine; Bergfeld, Leon; Niemeyer, Daniela; Mühlemann, Barbara; Conrad, Claudia; Dang-Heine, Chantip; Kasper, Stefanie; Münn, Friederike; Kappert, Kai; Nitsche, Andreas; Tauber, Rudolf; Schmidt, Sein; Kopankiewicz, Piotr; Bias, Harald; Seybold, Joachim; von Kalle, Christof; Jones, Terry C.; Suttorp, Norbert; Drosten, Christian; Sander, Leif Erik; Corman, Victor M.; Kurth, Florian

2021-06-08Zeitschriftenartikel

Schwarz, Tatjana

Tober-Lau, Pinkus

Hillus, David

Helbig, Elisa T.

Lippert, Lena J.

Thibeault, Charlotte

Koch, Willi

Landgraf, Irmgard

Michel, Janine

Bergfeld, Leon

Niemeyer, Daniela

Mühlemann, Barbara

Conrad, Claudia

Dang-Heine, Chantip

Kasper, Stefanie

Münn, Friederike

Kappert, Kai

Nitsche, Andreas

Tauber, Rudolf

Schmidt, Sein

Kopankiewicz, Piotr

Bias, Harald

Seybold, Joachim

von Kalle, Christof

Jones, Terry C.

Suttorp, Norbert

Drosten, Christian

Sander, Leif Erik

Corman, Victor M.

Kurth, Florian

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.

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