edoc.rki.de - Open Access Publikationsserver: Neuzugänge
Anzeige der Publikationen 221-240 von 12772
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2023-09-16ZeitschriftenartikelDe novo genome assembly resolving repetitive structures enables genomic analysis of 35 European Mycoplasmopsis bovis strains Mycoplasmopsis (M.) bovis, the agent of mastitis, pneumonia, and arthritis in cattle, harbors a small genome of approximately 1 Mbp. Combining data from Illumina and Nanopore technologies, we sequenced and assembled the ...
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2023-05-30ZeitschriftenartikelMolecular epidemiology and disease severity of influenza virus infection in patients with haematological disorders Influenza virus infection is a common cause of self-limiting respiratory tract infection (RTI), however immunocompromised patients are at an increased risk for a severe course of disease or fatal outcome. We therefore aimed ...
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2023-08-25ZeitschriftenartikelOptimization of HIV testing services in Germany using HIV indicator diseases: study protocol of the HeLP study Background: Despite the potentially accompanying negative clinical, epidemiologic, and health economic effects, a large proportion of persons living with the human immunodeficiency virus (HIV) are diagnosed late. ...
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2023-03-16ZeitschriftenartikelSpatiotemporal spread of tick-borne encephalitis in the EU/EEA, 2012 to 2020 Background: Tick-borne encephalitis (TBE) is a vaccine-preventable disease involving the central nervous system. TBE became a notifiable disease on the EU/EEA level in 2012. Aim: We aimed to provide an updated ...
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2023-02-03ZeitschriftenartikelStrategietreffen: Virushepatitis in Deutschland eliminieren – Was ist zu tun? Virushepatitis – ein (un-)lösbares Problem? Chronische Virushepatitiden stellen nach wie vor ein globales gesundheitliches Problem dar. Weltweit zählen insbesondere die chronische Hepatitis B (HBV)-Virusinfektion und ...
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2023-10-31ZeitschriftenartikelPlant-Associated Representatives of the Bacillus cereus Group Are a Rich Source of Antimicrobial Compounds Seventeen bacterial strains able to suppress plant pathogens have been isolated from healthy Vietnamese crop plants and taxonomically assigned as members of the Bacillus cereus group. In order to prove their potential as ...
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2023-03-31ZeitschriftenartikelDetection and genetic characterization of circoviruses in more than 80 bat species from eight countries on four continents Several bat-associated circoviruses and circular rep-encoding single-stranded DNA (CRESS DNA) viruses have been described, but the exact diversity and host species of these viruses are often unknown. Our goal was to describe ...
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2023-01-04ZeitschriftenartikelNanopore-Based Enrichment of Antimicrobial Resistance Genes – A Case-Based Study Rapid screening of hospital admissions to detect asymptomatic carriers of resistant bacteria can prevent pathogen outbreaks. However, the resulting isolates rarely have their genome sequenced due to cost constraints and ...
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2023-08-14ZeitschriftenartikelResults of German external quality assessment schemes for SARS-CoV-2 antigen detection The COVID-19 pandemic illustrated the important role of diagnostic tests, including lateral flow tests (LFTs), in identifying patients and their contacts to slow the spread of infections. INSTAND performed external quality ...
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2025-07-17ZeitschriftenartikelBeschluss und Wissenschaftliche Begründung der STIKO zur Erweiterung der Indikations- und beruflichen Indikationsempfehlung für die saisonale Influenza-Impfung Die STIKO hat die aktuelle Situation mit der weltweit starken Ausbreitung von hochpathogenen H5Nx-Viren unter Geflügel, Wasservögeln und anderen Wildvögeln sowie den vermehrten Nachweisen von H5Nx in diversen Säugetierklassen ...
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2025-07-17ZeitschriftenartikelBeschluss und wissenschaftliche Begründung der STIKO für die Anpassung der Empfehlungen zur Indikationsimpfung sowie zur postexpositionellen Impfung zum Schutz vor Mpox Die STIKO passt ihre Impfempfehlungen zum Schutz vor Mpox an. Wie das Epidemiologische Bulletin 29/2025 ausführt, ist der Impfstoff Imvanex seit 2024 für Personen ≥ 12 Jahre zugelassen und die Anwendungseinschränkung auf ...
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2025-07-17ZeitschriftenartikelSaison 2025 stechmückenübertragener Krankheitserreger in Deutschland beginnt Wie in den Vorjahren wird auch dieses Jahr im Epidemiologischen Bulletin 29/2025 wieder auf die beginnende Saison stechmückenübertragener Krankheitserreger hingewiesen. In Deutschland gibt es diesbezüglich zwei verschiedene ...
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2025-07-17ZeitschriftenartikelWochenbericht zur hitzebedingten Mortalität KW 27 Stand: Kalenderwoche 27/2025 (30.06. bis 06.07.2025)Hitzeperioden führen in Deutschland regelmäßig zu einem Anstieg der Mortalität. Um über die aktuelle Lage in Deutschland zu informieren, wird dieser Bericht während des Sommers 2025 (Juni-September) wöchentlich aktualisiert. ...
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2023-05-12ZeitschriftenartikelCombination of whole genome sequencing and supervised machine learning provides unambiguous identification of eae-positive Shiga toxin-producing Escherichia coli Introduction: The objective of this study was to develop, using a genome wide machine learning approach, an unambiguous model to predict the presence of highly pathogenic STEC in E. coli reads assemblies derived from complex ...
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2023-04-06ZeitschriftenartikelEffect of risk status for severe COVID-19 on individual contact behaviour during the SARS-CoV-2 pandemic in 2020/2021—an analysis based on the German COVIMOD study Background: One of the primary aims of contact restriction measures during the SARS-CoV-2 pandemic has been to protect people at increased risk of severe disease from the virus. Knowledge about the uptake of contact ...
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2023-02-13ZeitschriftenartikelAdvances towards the complete in vitro life cycle of Toxoplasma gondii The full life cycle of Toxoplasma gondii cannot be recapitulated in vitro, and access to certain stages, such as mature tissue cysts (bradyzoites) and oocysts (sporozoites), traditionally requires animal experiments. This ...
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2023-04-26ZeitschriftenartikelTaking hospital pathogen surveillance to the next level High-throughput bacterial genomic sequencing and subsequent analyses can produce large volumes of high-quality data rapidly. Advances in sequencing technology, with commensurate developments in bioinformatics, have increased ...
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2023-04-28ZeitschriftenartikelResults of the first German external quality assessment scheme for the detection of monkeypox virus DNA Background: In May 2022, the monkeypox virus (MPXV) spread into non-endemic countries and the global community was quick to test the lessons learned from the SARS-CoV-2 pandemic. Due to its symptomatic resemblance to ...
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2023-07-25ZeitschriftenartikelEvidence for positive long- and short-term effects of vaccinations against COVID-19 in wearable sensor metrics Vaccines are among the most powerful tools to combat the COVID-19 pandemic. They are highly effective against infection and substantially reduce the risk of severe disease, hospitalization, ICU admission, and death. However, ...
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2023-09-25ZeitschriftenartikelReflections from the COVID-19 pandemic in Germany: lessons for global health