edoc.rki.de - Open Access Publikationsserver: Recent submissions
Now showing items 1-20 of 13018
-
2024-12-03ZeitschriftenartikelImpfverhalten von Klinikpersonal verstehen – Ergebnisse der OKaPII-Studie 2023 Hintergrund: Das Potenzial der Influenza-Impfung zur Verhinderung der Erkrankung und Weiterverbreitung des Virus wird im klinischen Setting nicht ausgeschöpft. Ein Verständnis von Impfverhalten ist notwendig, um wirksame ...
-
2024-05-12ZeitschriftenartikelThe gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis Background: Enhancing our understanding of the underlying influences of medical interventions on the microbiome, resistome and mycobiome of preterm born infants holds significant potential for advancing infection ...
-
2024-03-20ZeitschriftenartikelGerman coasts harbor non-O1/non-O139 Vibrio cholerae with clinical virulence gene profiles Non-O1/non-O139 Vibrio cholerae (NOVC) are ubiquitous in aquatic ecosystems. In rare cases, they can cause intestinal and extra-intestinal infections in human. This ability is associated with various virulence factors. The ...
-
2024-06-14ZeitschriftenartikelCervical cancer trend in the Republic of Kazakhstan and attitudes towards cervical cancer screening in urban and rural areas Cervical cancer (CC) continues to be a significant global health issue, which in part can be attributed to disparities in access to CC screening services. This study aims to conduct a trend of CC in Kazakhstan and to compare ...
-
2024-08-29ZeitschriftenartikelCombining RNA Interference and RIG-I Activation to Inhibit Hepatitis E Virus Replication Hepatitis E virus (HEV) poses a significant global health threat, with an estimated 20 million infections occurring annually. Despite being a self-limiting illness, in most cases, HEV infection can lead to severe outcomes, ...
-
2024-01-10ZeitschriftenartikelImpact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin–angiotensin–aldosterone system on COVID-19 disease Background: The coronavirus disease 2019 (COVID-19) pandemic is driven by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which has led to an enormous burden on patient morbidity and mortality. ...
-
2024-02-11ZeitschriftenartikelDifferent metabolic adaptation strategies after overwintering in Eutrema sp. and Arabidopsis accessions under field conditions in Germany Successful overwintering is a prerequisite for high fitness in temperate perennials and winter annuals and is highly dependent on increased freezing tolerance and timely balancing of deacclimation with growth resumption ...
-
2026-02-12ZeitschriftenartikelEpidemiologische Untersuchung eines Norovirusausbruchs in Kindergemeinschaftseinrichtungen im Landkreis Göttingen im Jahr 2023
-
2024-07-12ZeitschriftenartikelgNOMO2: a comprehensive and modular pipeline for integrated multi-omics analyses of microbiomes Background: In recent years, omics technologies have offered an exceptional chance to gain a deeper insight into the structural and functional characteristics of microbial communities. As a result, there is a growing ...
-
2024-08-08ZeitschriftenartikelImpact of reference design on estimating SARS-CoV-2 lineage abundances from wastewater sequencing data Background: Sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA from wastewater samples has emerged as a valuable tool for detecting the presence and relative abundances of SARS-CoV-2 variants ...
-
2024-01-19ZeitschriftenartikeltANCHOR cell-based ELISA approach as a surrogate for antigen-coated plates to monitor specific IgG directed to the SARS-CoV-2 receptor-binding domain Enzyme-linked immunosorbent assay (ELISA) systems use plates coated with peptides or expressed and purified proteins to monitor immunoglobulins derived from patient serum. However, there is currently no easy, flexible, and ...
-
2024-12-23ZeitschriftenartikelEnd-to-end simulation of nanopore sequencing signals with feed-forward transformers Motivation: Nanopore sequencing represents a significant advancement in genomics, enabling direct long-read DNA sequencing at the single-molecule level. Accurate simulation of nanopore sequencing signals from nucleotide ...
-
2024-11-05ZeitschriftenartikelAssociation between Socioeconomic Position of the Family and Adolescent Obesity in Germany—Analysis of the Mediating Role of Familial Determinants Background: Obesity’s negative impact on young people’s health has long been known. The family and its socioeconomic position (SEP) are key determinants in adolescent obesity. However, understanding which familial determinants ...
-
2024-01-18ZeitschriftenartikelA look at staphylococci from the one health perspective Staphylococcus aureus and other staphylococcal species are resident and transient multihost colonizers as well as conditional pathogens. Especially S. aureus represents an excellent model bacterium for the “One Health” ...
-
2024-02-13ZeitschriftenartikelOutpatient Health Service Utilization Among Adults with Diabetes, Hypertension and Cardiovascular Disease During the COVID-19 Pandemic – Results of Population-Based Surveys in Germany from 2019 to 2021 Purpose: Fear of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and lockdown measures may have an impact on health care utilization particularly for people with chronic diseases. We investigated ...
-
2024-07-30ZeitschriftenartikelA nested model for AI design and validation The growing AI field faces trust, transparency, fairness, and discrimination challenges. Despite the need for new regulations, there is a mismatch between regulatory science and AI, preventing a consistent framework. A ...
-
2024-01-04ZeitschriftenartikelRecombination-aware phylogenetic analysis sheds light on the evolutionary origin of SARS-CoV-2 SARS-CoV-2 can infect human cells through the recognition of the human angiotensin-converting enzyme 2 receptor. This affinity is given by six amino acid residues located in the variable loop of the receptor binding domain ...
-
2024-02-01ZeitschriftenartikelGenomic surveillance of STEC/EHEC infections in Germany 2020 to 2022 permits insight into virulence gene profiles and novel O-antigen gene clusters Shiga toxin-producing E. coli (STEC), including the subgroup of enterohemorrhagic E. coli (EHEC), are important bacterial pathogens which cause diarrhea and the severe clinical manifestation hemolytic uremic syndrome (HUS). ...
-
2024-01-11ZeitschriftenartikelDifferent populations of A(H1N1)pdm09 viruses in a patient with hemolytic-uremic syndrome Respiratory viral infections may have different impacts ranging from infection without symptoms to severe disease or even death though the reasons are not well characterized. A patient (age group 5–15 years) displaying ...
-
2024-07-10ZeitschriftenartikelEffectiveness and duration of protection of primary and booster immunisation against meningococcal serogroup C disease with meningococcal conjugate C and ACWY vaccines: Systematic review Objectives: To estimate vaccine effectiveness (VE) and duration of protection of single primary and booster immunisation with meningococcal C (MenC) and ACWY (MenACWY) conjugate vaccines in preventing MenC invasive ...