edoc.rki.de - Open Access Publikationsserver: Recent submissions
Now showing items 341-360 of 12079
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2021-03-01ZeitschriftenartikelThe relationship of self-reported and device-based measures of physical activity and health-related quality of life in adolescents Background Physical activity (PA) has beneficial effects on health and health-related quality of life (HRQoL), which is a protective factor of illness and mortality. The purpose of this examination was to investigate ...
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2021-05-18ZeitschriftenartikelTransformation of microbiology data into a standardised data representation using OpenEHR The spread of multidrug resistant organisms (MDRO) is a global healthcare challenge. Nosocomial outbreaks caused by MDRO are an important contributor to this threat. Computer-based applications facilitating outbreak detection ...
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2021-09-02ZeitschriftenartikelSmall-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding Measles virus (MeV) is a highly contagious pathogen that enters the human host via the respiratory route. Besides acute pathologies including fever, cough and the characteristic measles rash, the infection of lymphocytes ...
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2021-02-17ZeitschriftenartikelSocial networks predict the life and death of honey bees In complex societies, individuals’ roles are reflected by interactions with other conspecifics. Honey bees (Apis mellifera) generally change tasks as they age, but developmental trajectories of individuals can vary drastically ...
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2021-03-15ZeitschriftenartikelDiscovery of Novel Herpes Simplexviruses in Wild Gorillas, Bonobos, and Chimpanzees Supports Zoonotic Origin of HSV-2 Viruses closely related to human pathogens can reveal the origins of human infectious diseases. Human herpes simplexvirus type 1 (HSV-1) and type 2 (HSV-2) are hypothesized to have arisen via host-virus codivergence and ...
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2021-05-26ZeitschriftenartikelSwarm Learning for decentralized and confidential clinical machine learning Fast and reliable detection of patients with severe and heterogeneous illnesses is a major goal of precision medicine1,2. Patients with leukaemia can be identified using machine learning on the basis of their blood ...
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2021-09-26ZeitschriftenartikelSocioeconomic inequalities in the prevalence and perceived dangerousness of SARS-CoV-2 infections in two early German hotspots: findings from a seroepidemiological study Objective Evidence on socioeconomic inequalities in infections with the novel coronavirus (SARS-CoV-2) is still limited as most of the available studies are ecological in nature and individual-level data is sparse. We ...
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2021-03-30ZeitschriftenartikelThe global dissemination of hospital clones of Enterococcus faecium Background The hospital-adapted A1 group of Enterococcus faecium remains an organism of significant concern in the context of drug-resistant hospital-associated infections. How this pathogen evolves and disseminates ...
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2021-01-06ZeitschriftenartikelThe Status under EU Law of Organisms Developed through Novel Genomic Techniques In a ruling on 25 July 2018, the Court of Justice of the European Union concluded that organisms obtained by means of techniques/methods of mutagenesis constitute GMOs in the sense of Directive 2001/18, and that organisms ...
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2021-12-15ZeitschriftenartikelCritical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows Metaproteomics has matured into a powerful tool to assess functional interactions in microbial communities. While many metaproteomic workflows are available, the impact of method choice on results remains unclear. Here, ...
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2021-10-14ZeitschriftenartikelIndividual social contact data and population mobility data as early markers of SARS-CoV-2 transmission dynamics during the first wave in Germany—an analysis based on the COVIMOD study Background The effect of contact reduction measures on infectious disease transmission can only be assessed indirectly and with considerable delay. However, individual social contact data and population mobility data ...
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2021-09-02ZeitschriftenartikelImpact of the COVID-19 pandemic on the surveillance, prevention and control of antimicrobial resistance: a global survey Objectives The COVID-19 pandemic has had a substantial impact on health systems. The WHO Antimicrobial Resistance (AMR) Surveillance and Quality Assessment Collaborating Centres Network conducted a survey to assess the ...
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2021-04-24ZeitschriftenartikelTransmissible α-synuclein seeding activity in brain and stomach of patients with Parkinson’s disease Cerebral deposition of abnormally aggregated α-synuclein (αSyn) is a neuropathological hallmark of Parkinson’s disease (PD). PD-associated αSyn (αSynPD) aggregates can act as proteinaceous nuclei (“seeds”) able of ...
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2021-05-06ZeitschriftenartikelCorrection to: Transmissible α‑synuclein seeding activity in brain and stomach of patients with Parkinson’s disease
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2021-12-22ZeitschriftenartikelOverview of national health reporting in the EU and quality criteria for public health reports – results of the Joint Action InfAct Background Health reporting shall provide up-to-date health-related data to inform policy-makers, researchers and the public. To this end, health reporting formats should be tailored to the needs and competencies of the ...
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2021-08-10ZeitschriftenartikelInvestigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report Background The true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far have been recorded in Bavaria, southern Germany. Case presentation A ...
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2021-09-21ZeitschriftenartikelComparison of MICs in Escherichia coli isolates from human health surveillance with MICs obtained for the same isolates by broth microdilution Objectives Human health surveillance and food safety monitoring systems use different antimicrobial susceptibility testing (AST) methods. In this study, we compared the MICs of Escherichia coli isolates provided by these ...
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2021-07-27ZeitschriftenartikelQuorum sensing governs a transmissive Legionella subpopulation at the pathogen vacuole periphery The Gram‐negative bacterium Legionella pneumophila is the causative agent of Legionnaires' disease and replicates in amoebae and macrophages within a distinct compartment, the Legionella‐containing vacuole (LCV). The ...
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2021-08-03ZeitschriftenartikelCorrection to: Treatment modifcation after starting cART in people living with HIV: retrospective analysis of the German ClinSurv HIV Cohort 2005–2017
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2021-04-20ZeitschriftenartikelDiscrete choice experiment to determine preferences of decision-makers in healthcare for different formats of rapid reviews Background Time-saving formats of evidence syntheses have been developed to fulfill healthcare policymakers’ demands for timely evidence-based information. A discrete choice experiment (DCE) with decision-makers and ...