edoc.rki.de - Open Access Publikationsserver: Neuzugänge
Anzeige der Publikationen 11541-11560 von 12823
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2012-11-06ZeitschriftenartikelHeterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) Gene and Metabolic Risk Factors in the EPIC-Potsdam Study Background: Stearoyl-CoA desaturase-1 (SCD1) is an enzyme involved in lipid metabolism. In mice and humans its activity has been associated with traits of the metabolic syndrome, but also with the prevention of saturated ...
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2012-11-09ZeitschriftenartikelSerum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols Robust and sensitive ELISPOT protocols are commonly applied concomitant with the development of new immunotherapeutics. Despite the knowledge that individual serum batches differ in their composition and may change properties ...
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2012-05-14ZeitschriftenartikelFeatures of “All LNA” Duplexes Showing a New Type of Nucleic Acid Geometry "Locked nucleic acids" (LNAs) belong to the backbone-modified nucleic acid family. The 2'-O,4'-C-methylene-β-D-ribofuranose nucleotides are used for single or multiple substitutions in RNA molecules and thereby introduce ...
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2011-11-09ZeitschriftenartikelMolecular interactions of porcine circoviruses type 1 and type 2 with its host This review discusses the molecular interaction of proteins encoded by porcine circoviruses type 1 (PCV1) and type 2 (PCV2) with respect to the putative role for disease induction. Besides protein:protein interactions also ...
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2012-10-01ZeitschriftenartikelKurzfristige Prognosen der Krebsmortalität in Deutschland bis 2015 German short-term cancer mortality predictions up until 2015Seit vielen Jahren ist die Krebssterblichkeit (Krebsmortalität) insgesamt bei Männern und Frauen in Deutschland erfreulich rückläufig und wird sich dieser Schätzung zufolge auch in den nächsten Jahren so weiterentwickeln. ...
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2012-08-22ZeitschriftenartikelInduction of Antibodies Specific for Gp41 of HIV-1 by Gene Gun DNA Vaccination All attempts to induce broadly neutralising antibodies such as mAb 2F5 and mAb 4E10 targeting conserved epitopes in the membrane proximal external region (MPER) of the transmembrane envelope (TM) protein gp41 of HIV-1 ...
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2011-11-09ZeitschriftenartikelRNA interference inhibits replication of tick-borne encephalitis virus in vitro. Each year, up to 10,000 cases of infections with the flavivirus tick-borne encephalitis (TBE) virus that affect the central nervous system are reported in Europe and Asia. Due to the potentially severe adverse effects of ...
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2005-02-01ZeitschriftenartikelHuman immunodeficiency virus, hepatitis C and hepatitis B infections among blood donors in Germany 2000-2002: risk of virus transmission and the impact of nucleic acid amplification testing. Blood and plasma donations in Germany are collected by several institutions, namely the German Red Cross, community and hospital-based blood services, private blood centres, commercial plasma donation sites and transfusion ...
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2005-03-01ZeitschriftenartikelVariante Creutzfeld-Jakob-Erkrankung (vCJK) und Transfusionsmedizin Konsequenzen für die Sicherheit von BlutproduktenIm Dezember 2003 wurde bekannt, dass in Großbritannien ein Patient an der Variante Creutzfeld-Jakob-Erkrankung (vCJK) verstorben war, der 6 1/2 Jahre zuvor ein Erythrozytenkonzentrat von einem Spender erhalten hatte, der ...
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2007-10-05ZeitschriftenartikelInfektionsepidemiologische Daten von Blutspendern 2005 Bericht des Robert Koch-Instituts zu den Meldungen nach § 22 TransfusionsgesetzDie Erhebung infektionsepidemiologischer Daten zur Bestimmung der Prävalenz und Inzidenz von HIV-, Hepatitis-C-Virus-(HCV-), Hepatitis-B-Virus-(HBV-) und Syphilisinfektionen im Blut- und Plasmaspendewesen in Deutschland ...
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2011-07-01ZeitschriftenartikelDer einheitliche Spenderfragebogen Seit Februar 2011 steht ein einheitlicher Blutspenderfragebogen für Blut- und Plasmaspender in Deutschland zur Verfügung. Dieser wurde im Auftrag des Arbeitskreises Blut von einer Expertengruppe entwickelt. Der Fragebogen ...
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2012-09-04ZeitschriftenartikelGerman health interview and examination survey for adults (DEGS) - design, objectives and implementation of the first data collection wave Background: The German Health Interview and Examination Survey for Adults (DEGS) is part of the recently established national health monitoring conducted by the Robert Koch Institute. DEGS combines a nationally ...
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2011-10-15ZeitschriftenartikelEpidemiologie des EHEC O104:H4/HUS-Ausbruchs in Deutschland, Mai bis Juli 2011 Von Mai bis Juli 2011 ereignete sich vor allem in Norddeutschland der bisher größte Ausbruch von Infektionen durch enterohämorrhagische Escherichia coli (EHEC) O104:H4 und von hämolytisch-urämischem Syndrom (HUS) mit ...
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2007-05-25ZeitschriftenartikelFepA- and TonB-dependent bacteriophage H8: receptor binding and genomic sequence. H8 is derived from a collection of Salmonella enterica serotype Enteritidis bacteriophage. Its morphology and genomic structure closely resemble those of bacteriophage T5 in the family Siphoviridae. H8 infected S. enterica ...
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2010-05-14ZeitschriftenartikelPork contaminated with Salmonella enterica serovar 4,[5],12:i:-, an emerging health risk for humans. Salmonella enterica subsp. enterica serovar 4,[5],12:i:- is a monophasic variant of S. enterica serovar Typhimurium (antigenic formula 4,[5],12:i:1,2). Worldwide, especially in several European countries and the United ...
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2009-07-22ZeitschriftenartikelMeasles viruses of genotype H1 evade recognition by vaccine-induced neutralizing antibodies targeting the linear haemagglutinin noose epitope The linear haemagglutinin noose epitope (HNE; aa 379-410) is a protective B-cell epitope and considered to be highly conserved in both the vaccine and the wild-type measles virus (MeV) haemagglutinin (H) proteins. Vaccine ...
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2009-02-25ZeitschriftenartikelCross-talk between type three secretion system and metabolism in Yersinia. Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and YscM2 proteins have been reported to be functionally equivalent ...
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2007-11-01ZeitschriftenartikelPrävention von Übergewicht bei Kindern und Jugendlichen Hintergrund: Übergewicht und Adipositas sind ein wachsendes Gesundheitsproblem, welches heute bei Kindern, Jugendlichen und Erwachsenen endemisch ist. Deshalb ist eine Prävention von Übergewicht dringend notwendig. Die ...
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2011-04-06ZeitschriftenartikelCytomegalovirus e127 protein interacts with the inhibitory CD200 receptor. CD200 is a cell surface glycoprotein that binds an inhibitory receptor (CD200R) on myeloid cells. CD200 orthologues are present in many species of virus, and we show that the rat cytomegalovirus CD200 orthologue (e127) is ...
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2011-06-28ZeitschriftenartikelMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site The protein machinery of neurotransmitter exocytosis requires efficient orchestration in space and time, for speed and precision of neurotransmission and also for synaptic ontogeny and plasticity. However, its spatial ...