Auflistung nach Titel
Anzeige der Publikationen 6157-6176 von 11520
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2013-01-30ZeitschriftenartikelModulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1 The transmembrane envelope protein gp41 of the human immunodeficiency virus HIV-1 plays an important role during infection allowing fusion of the viral and cellular membrane. In addition, there is increasing evidence that ...
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2014-01-30ZeitschriftenartikelMolecular Analysis of Human Metapneumovirus Detected in Patients with Lower Respiratory Tract Infection in Upper Egypt Introduction: Since 2001, when Human metapneumovirus (HMPV) was isolated in the Netherlands, the virus has been detected in several continents. Although reports have confirmed the prevalence of HMPV worldwide, data from ...
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2011-05-11ZeitschriftenartikelMolecular analysis of varicella vaccines and varicella-zoster virus from vaccine-related skin lesions. To prevent complications that might follow an infection with varicella-zoster virus (VZV), the live attenuated Oka strain (V-Oka) is administered to children in many developed countries. Three vaccine brands (Varivax from ...
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2019-08-08ZeitschriftenartikelMolecular and epidemiological characteristics of human Puumala and Dobrava-Belgrade hantavirus infections, Germany, 2001 to 2017 Introduction Two hantavirus species, Puumala (PUUV) and Dobrava-Belgrade (DOBV) virus (genotype Kurkino), are endemic in Germany. Recent PUUV outbreaks raised questions concerning increasing frequency of outbreaks and ...
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2019-03-13ZeitschriftenartikelMolecular and genomic typing for tuberculosis surveillance: A survey study in 26 European countries Background Molecular typing and whole genome sequencing (WGS) information is used for (inter-) national outbreak investigations. To assist the implementation of these techniques for tuberculosis (TB) surveillance and ...
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2020-02-16ZeitschriftenartikelMolecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana In the post-polio eradication era, increasing attention is given to non-polio enteroviruses. Most of the data about enteroviruses in sub-Saharan Africa are related to acute flaccid paralysis surveillance and target the ...
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2011-06-21ZeitschriftenartikelMolecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007 Objectives: To investigate the genetic environment of the metallo-β-lactamase gene blaNDM-1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods: Antimicrobial susceptibility testing was performed ...
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2019-09-13ZeitschriftenartikelMolecular Characterization of Equine Staphylococcus aureus Isolates Exhibiting Reduced Oxacillin Susceptibility The detection of borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a challenge to both, veterinary and human laboratories. Between 2015 and 2017, 19 equine S. aureus with elevated minimal inhibitory ...
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2023-05-30ZeitschriftenartikelMolecular epidemiology and disease severity of influenza virus infection in patients with haematological disorders nfluenza virus infection is a common cause of self‐limiting respiratory tract infection(RTI), however immunocompromised patients are at an increased risk for a severecourse of disease or fatal outcome. We therefore aimed ...
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2021-04-30ZeitschriftenartikelMolecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most ...
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2014-05-16ZeitschriftenartikelMolecular Epidemiology and Genotyping of Hepatitis B Virus of HBsAg-Positive Patients in Oman Background: Hepatitis B virus (HBV) infection is a major global health burden with distinct geographic public health significance. Oman is a country with intermediate HBV carrier prevalence; however, little is known ...
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2016-01-14ZeitschriftenartikelMolecular epidemiology of hepatitis D virus circulating in Southwestern Nigeria Background: Hepatitis B virus (HBV) and hepatitis D virus (HDV) infections are major public health problems in sub-Saharan Africa. Whereas it is known that HBV infection is endemic in Nigeria, there is only little data ...
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2020-01-24ZeitschriftenartikelMolecular Epidemiology of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Wild, Captive and Laboratory Rats: Effect of Habitat on the Nasal S. aureus Population Rats are a reservoir of human- and livestock-associated methicillin-resistant Staphylococcus aureus (MRSA). However, the composition of the natural S. aureus population in wild and laboratory rats is largely unknown. Here, ...
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2005-04-29ZeitschriftenartikelMolecular epidemiology of Salmonella enterica serovar Agona: characterization of a diffuse outbreak caused by aniseed-fennel-caraway infusion During 2002-2003 increased numbers of notified salmonellosis due to S. enterica serovar Agona were observed in Germany. In order to understand the recent spread of this serovar and to trace the route of infection to its ...
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2017-11-14ZeitschriftenartikelMolecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors Background: Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set ...
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2019-01-31ZeitschriftenartikelMolecular Evolution of Human Adenovirus (HAdV) Species C Currently, 88 different Human Adenovirus (HAdV) types are grouped into seven HAdV species A to G. Most types (57) belong to species HAdV-D. Recombination between capsid genes (hexon, penton and fiber) is the main factor ...
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2018-11-15ZeitschriftenartikelMolecular Genetic and Functional Analysis of pks-Harboring, Extra-Intestinal Pathogenic Escherichia coli From India Colibactin, a genotoxin, encoded by the pks pathogenicity island of Escherichia coli belonging to the B2 phylogroup has been reported as a determinant of bacterial pathogenicity. The present study was carried out to detect ...
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2011-07-01ZeitschriftenartikelMolecular genotyping and epidemiology of measles virus transmission in the World Health Organization European Region, 2007-2009 Background: In 2002, the World Health Organization (WHO) adopted a goal to eliminate measles in the European Region by 2010. Measles elimination is defined as the interruption of indigenous measles virus (MV) transmission. ...
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2019-03-15ZeitschriftenartikelMolecular identification of the source of an uncommon tularaemia outbreak, Germany, autumn 2016 Background In 2016, an uncommon outbreak of oropharyngeal tularaemia involving six human cases occurred in Germany, caused by drinking contaminated fresh must after a grape harvest. Aim We describe the details of ...
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2011-06-28ZeitschriftenartikelMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site The protein machinery of neurotransmitter exocytosis requires efficient orchestration in space and time, for speed and precision of neurotransmission and also for synaptic ontogeny and plasticity. However, its spatial ...