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Auflistung Artikel in Fachzeitschriften nach Autor "Kirchner, Sebastian"
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2012-03-07ZeitschriftenartikelDe novo subtype and strain identification of botulinum neurotoxin type B through toxin proteomics Kalb, Suzanne R.; Baudys, Jakub; Rees, Jon C.; Smith, Theresa J.; Smith, Leonard A.; Helma, Charles H.; Hill, Karen; Kull, Skadi; Kirchner, Sebastian; Dorner, Martin; Dorner, Brigitte; Pirkle, James L.; Barr, John R.Botulinum neurotoxins (BoNTs) cause the disease botulism, which can be lethal if untreated. There are seven known serotypes of BoNT, A–G, defined by their response to antisera. Many serotypes are distinguished into differing ...
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2015-02-06ZeitschriftenartikelIsolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype Kull, Skadi; Schulz, Melanie; Strotmeier, Jasmin Weisemann née; Kirchner, Sebastian; Schreiber, Tanja; Bollenbach, Alexander; Dabrowski, Piotr Wojtek; Nitsche, Andreas; Kalb, Suzanne R.; Dorner, Martin; Barr, John R.; Rummel, Andreas; Dorner, BrigitteBotulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed ...
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2010-04-30ZeitschriftenartikelPentaplexed quantitative real-time PCR assay for the simultaneous detection and quantification of botulinum neurotoxin-producing clostridia in food and clinical samples Kirchner, Sebastian; Krämer, Melanie; Schulze, Martin; Pauly, Diana; Jacob, Daniela; Gessler, Frank; Nitsche, Andreas; Dorner, Brigitte; Dorner, MartinBotulinum neurotoxins are produced by the anaerobic bacterium Clostridium botulinum and are divided into seven distinct serotypes (A to G) known to cause botulism in animals and humans. In this study, a multiplexed ...
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2012-04-19ZeitschriftenartikelReal-time cytotoxicity assay for rapid and sensitive detection of ricin from complex matrices. Pauly, Diana; Worbs, Sylvia; Kirchner, Sebastian; Shatohina, Olena; Dorner, Martin; Dorner, BrigitteBackground: In the context of a potential bioterrorist attack sensitive and fast detection of functionally active toxins such as ricin from complex matrices is necessary to be able to start timely countermeasures. One of ...
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2009-08-21ZeitschriftenartikelSimultaneous quantification of five bacterial and plant toxins from complex matrices using a multiplexed fluorescent magnetic suspension assay Pauly, Diana; Kirchner, Sebastian; Stoermann, Britta; Schreiber, Tanja; Kaulfuss, Stefan; Schade, Rüdiger; Zbinden, Reto; Avondet, Marc-André; Dorner, Martin; Dorner, BrigitteProteotoxins such as ricin, abrin, botulinum neurotoxins type A and B (BoNT/A, BoNT/B) and staphylococcal enterotoxin B (SEB) are regarded as potential biological warfare agents which could be used for bioterrorism attacks ...