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Browsing Artikel in Fachzeitschriften by Author "Meixenberger, Karolin"
Now showing items 1-16 of 16
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2016-01-12ZeitschriftenartikelA Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing John, Elizabeth P. St.; Simen, Birgitte B.; Turenchalk, Gregory S.; Braverman, Michael S.; Abbate, Isabella; Aerssens, Jeroen; Bouchez, Olivier; Gabriel, Christian; Izopet, Jacques; Meixenberger, Karolin; Giallonardo, Francesca Di; Schlapbach, Ralph; Paredes, Roger; Sakwa, James; Schmitz-Agheguian, Gudrun G.; Thielen, Alexander; Victor, Martin; Metzner, Karin J.; Däumer, Martin P.Background: Ultra deep sequencing is of increasing use not only in research but also in diagnostics. For implementation of ultra deep sequencing assays in clinical laboratories for routine diagnostics, intra- and ...
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2020-05-27ZeitschriftenartikelA Recent Human Immunodeficiency Virus Outbreak Among People Who Inject Drugs in Munich, Germany, Is Associated With Consumption of Synthetic Cathinones Hanke, Kirsten; Fiedler, Stefan; Grumann, Christina; Ratmann, Oliver; Hauser, Andrea; Klink, Patrycja; Meixenberger, Karolin; Altmann, Britta; Zimmermann, Ruth; Marcus, Ulrich; Bremer, Viviane; Auwärter, Volker; Bannert, NorbertBackground. Needle and syringe sharing among people who inject drugs (PWID) can result in a rapid regional spread of a human immunodeficiency virus (HIV) variant. Such outbreaks have been identified recently in several ...
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2014-11-02ZeitschriftenartikelCharacterization of natural polymorphic sites of the HIV-1 integrase before the introduction of HIV-1 integrase inhibitors in Germany Meixenberger, Karolin; Yousef, Kaveh Pouran; Somogyi, Sybille; Fiedler, Stefan; Bartmeyer, Barbara; Kleist, Max von; Kücherer, Claudia
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2020-02-08ZeitschriftenartikelComparative multi-assay evaluation of Determine™ HIV-1/2 Ag/Ab Combo rapid diagnostic tests in acute and chronic HIV infection Wratil, Paul R.; Rabenau, Holger F.; Eberle, Josef; Stern, Marcel; Münchhoff, Maximilian; Friedrichs, Imke; Stürmer, Martin; Bergerq, Annemarie; Kuttner-May, Susanne; Münstermann, Dieter; Lucht, Andreas; Meixenberger, Karolin; Bannert, Norbert; Keppler, Oliver T.In resource-limited or point-of-care settings, rapid diagnostic tests (RDTs), that aim to simultaneously detect HIV antibodies and p24 capsid (p24CA) antigen with high sensitivity, can pose important alternatives to screen ...
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2015-10-15ZeitschriftenartikelComparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission Hauser, Andrea; Kücherer, Claudia; Kunz, Andrea; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Theuring, Stefanie; Bannert, Norbert; Sewangi, Julius; Mbezi, Paulina; Dugange, Festo; Harms, Gundel; Meixenberger, KarolinBackground: Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study ...
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2017-05-31ZeitschriftenartikelDecreased emergence of HIV-1 drug resistance mutations in a cohort of Ugandan women initiating option B+ for PMTCT Machnowska, Patrycja; Hauser, Andrea; Meixenberger, Karolin; Altmann, Britta; Bannert, Norbert; Rempis, Eva; Schnack, Alexandra; Decker, Sarah; Braun, Vera; Busingye, Priscilla; Rubaihayo, John; Harms, Gundel; Theuring, StefanieBackground: Since 2012, WHO guidelines for the prevention of mother-to-child transmission (PMTCT) of HIV-1 in resource-limited settings recommend the initiation of lifelong antiretroviral combination therapy (cART) for ...
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2023-11-23ZeitschriftenartikelEinfluss des Kriegs in der Ukraine auf gemeldete HIV-Neudiagnosen in Deutschland Koppe, Uwe; Hanke, Kirsten; Meixenberger, Karolin; Bremer, Viviane; Gunsenheimer- Bartmeyer, BarbaraDie HIV-Prävalenz in der Ukraine wurde im Jahr 2019 bezogen auf die Gesamtbevölkerung auf 0,9 – 1,0 % geschätzt, wobei die Prävalenz in bestimmten vulnerablen Gruppen deutlich höher liegen dürfte. Durch den Angriffskrieg ...
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2014-08-22ZeitschriftenartikelEstimating Trends in the Proportion of Transmitted and Acquired HIV Drug Resistance in a Long Term Observational Cohort in Germany Schmidt, Daniel; Kollan, Christian; Fätkenheuer, Gerd; Schülter, Eugen; Stellbrink, Hans-Jürgen; Noah, Christian; Jensen, Björn-Erik Ole; Stoll, Matthias; Bogner, Johannes R.; Eberle, Josef; Meixenberger, Karolin; Kücherer, Claudia; Hamouda, Osamah; Bartmeyer, BarbaraObjective: We assessed trends in the proportion of transmitted (TDR) and acquired (ADR) HIV drug resistance and associated mutations between 2001 and 2011 in the German ClinSurv-HIV Drug Resistance Study. Method: ...
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2014-05-01ZeitschriftenartikelFirst Line Treatment Response in Patients with Transmitted HIV Drug Resistance and Well Defined Time Point of HIV Infection: Updated Results from the German HIV-1 Seroconverter Study Knyphausen, Fabia zu; Scheufele, Ramona; Kücherer, Claudia; Jansen, Klaus; Somogyi, Sybille; Dupke, Stephan; Jessen, Heiko; Schürmann, Dirk; Hamouda, Osamah; Meixenberger, Karolin; Bartmeyer, BarbaraBackground: Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided ...
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2015-11-10ZeitschriftenartikelHigh Prevalence and High Incidence of Coinfection with Hepatitis B, Hepatitis C, and Syphilis and Low Rate of Effective Vaccination against Hepatitis B in HIV-Positive Men Who Have Sex with Men with Known Date of HIV Seroconversion in Germany Jansen, Klaus; Thamm, Michael; Bock, Thomas; Scheufele, Ramona; Kücherer, Claudia; Muenstermann, Dieter; Hagedorn, Hans-Jochen; Jessen, Heiko; Dupke, Stephan; Hamouda, Osamah; Gunsenheimer-Bartmeyer, Barbara; Meixenberger, KarolinObjectives: Men who have sex with men (MSM) are at higher risk for coinfection with hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis than the general population. HIV infection and these coinfections ...
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2019-12-05ZeitschriftenartikelHIV-Studien und HIV-Projekte am Robert Koch-Institut Koppe, Uwe; Hanke, Kirsten; Fiebig, Uwe; Schmidt, Daniel; Meixenberger, Karolin; Pantke, Annemarie; Gunsenheimer-Bartmeyer, Barbara; Kollan, Christian; Kühne, Andrea; Marcus, Ulrich; Bannert, Norbert; Bremer, VivianeNeben der gesetzlich geregelten Surveillance von HIV-Neudiagnosen in Deutschland erfolgt am RKI auch die Durchführung verschiedener Studienprojekte, die im Epidemiologischen Bulletin 49/2019 vorgestellt werden. Das Rückgrat ...
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2014-06-03ZeitschriftenartikelImproved Testing of Recent HIV-1 Infections with the BioRad Avidity Assay Compared to the Limiting Antigen Avidity Assay and BED Capture Enzyme Immunoassay: Evaluation Using Reference Sample Panels from the German Seroconverter Cohort Hauser, Andrea; Santos-Hövener, Claudia; Meixenberger, Karolin; Zimmermann, Ruth; Somogyi, Sybille; Fiedler, Stefan; Hofmann, Alexandra; Bartmeyer, Barbara; Jansen, Klaus; Hamouda, Osamah; Bannert, Norbert; Kücherer, ClaudiaBackground: The variety and limitations of current laboratory methods for estimating HIV-incidence has driven attempts to improve and standardize the performance of serological ‘Tests for Recent HIV-Infections’ (TRI). ...
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2023-10-02ZeitschriftenartikelIncreasing hepatitis B vaccination coverage and decreasing hepatitis B co-infection prevalence among people with HIV-1 in Germany, 1996–2019. Results from a cohort study primarily in men who have sex with men Amrei, Krings; Schmidt, Daniel; Christian, Kollan; Meixenberger, Karolin; Bannert, Norbert; Tiemann, C.; Münstermann, D.; Bremer, Viviane; Gunsenheimer-Bartmeyer, BarbaraObjectives Viral hepatitis co-infection among people living with HIV is known to accelerate the progression of liver disease and AIDS. An increased prevalence and incidence of hepatitis B virus (HBV) infection among ...
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2018-11-08ZeitschriftenartikelIncreasing proportions of HIV-1 non-B subtypes and of NNRTI resistance between 2013 and 2016 in Germany: Results from the national molecular surveillance of new HIV-diagnoses Hauser, Andrea; Hofmann, Alexandra; Meixenberger, Karolin; Altmann, Britta; Hanke, Kirsten; Bremer, Viviane; Bartmeyer, Barbara; Bannert, NorbertBackground Molecular surveillance of newly diagnosed HIV-infections is important for tracking trends in circulating HIV-variants, including those with transmitted drug resistances (TDR) to sustain ART efficacy. Methods Dried ...
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2017-11-14ZeitschriftenartikelMolecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors Meixenberger, Karolin; Yousef, Kaveh Pouran; Smith, Maureen Rebecca; Somogyi, Sybille; Fiedler, Stefan; Bartmeyer, Barbara; Hamouda, Osamah; Bannert, Norbert; Kleist, Max von; Kücherer, ClaudiaBackground: Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set ...
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2019-01-16ZeitschriftenartikelPrevalence and persistence of transmitted drug resistance mutations in the German HIV-1 Seroconverter Study Cohort Machnowska, Patrycja; Meixenberger, Karolin; Schmidt, Daniel; Jessen, Heiko; Hillenbrand, Heribert; Gunsenheimer-Bartmeyer, Barbara; Hamouda, Osamah; Kücherer, Claudia; Bannert, NorbertThe prevalence of transmitted drug resistance (TDR) in antiretroviral therapy (ART)-naïve individuals remains stable in most developed countries despite a decrease in the prevalence of acquired drug resistance. This suggests ...