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Auflistung Artikel in Fachzeitschriften nach Autor "Fuchs, Stephan"
Anzeige der Publikationen 1-20 von 28
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2020-11-28ZeitschriftenartikelA Multi-Omics Protocol for Swine Feces to Elucidate Longitudinal Dynamics in Microbiome Structure and Function Riedel, Katharina; Gierse, Laurin Christopher; Meene, Alexander; Schultz, Daniel; Schwaiger, Theresa; Karte, Claudia; Schröder, Charlotte; Wang, Haitao; Wünsche, Christine; Methling, Karen; Kreikemeyer, Bernd; Fuchs, Stephan; Bernhardt, Jörg; Becher, Dörte; Lalk, Michael; Urich, Tim; KoInfekt Study GroupSwine are regarded as promising biomedical models, but the dynamics of their gastrointestinal microbiome have been much less investigated than that of humans or mice. The aim of this study was to establish an integrated ...
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2016-02-19ZeitschriftenartikelA Staphylococcus aureus Proteome Overview: Shared and Specific Proteins and Protein Complexes from Representative Strains of All Three Clades Liang, Chunguang; Schaack, Dominik; Srivastava, Mugdha; Gupta, Shishir K.; Sarukhanyan, Edita; Giese, Anne; Pagels, Martin; Romanov, Natalie; Pané-Farré, Jan; Fuchs, Stephan; Dandekar, ThomasStaphylococcus aureus is an important model organism and pathogen. This S. aureus proteome overview details shared and specific proteins and selected virulence-relevant protein complexes from representative strains of all ...
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2017-11-24ZeitschriftenartikelAureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community Fuchs, Stephan; Mehlan, Henry; Bernhardt, Jörg; Hennig, André; Michalik, Stephan; Surmann, Kristin; Pané-Farré, Jan; Giese, Anne; Weiss, Stefan; Backert, Linus; Herbig, Alexander; Nieselt, Kay; Hecker, Michael; Völker, Uwe; Mäder, UlrikeIn light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med ...
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2018-01-24ZeitschriftenartikelComparative analysis of Salivette® and paraffin gum preparations for establishment of a metaproteomics analysis pipeline for stimulated human saliva Rabe, Alexander; Salazar, Manuela Gesell; Fuchs, Stephan; Kocher, Thomas; Völker, UweThe value of saliva as a diagnostic tool can be increased by taxonomic and functional analyses of the microbiota as recently demonstrated. In this proof-of-principle study, we compare two collection methods (Salivette® ...
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2016-06-17ZeitschriftenartikelComparison of six commercial kits to extract bacterial chromosome and plasmid DNA for MiSeq sequencing Becker, Laura; Steglich, Matthias; Fuchs, Stephan; Werner, Guido; Nübel, UlrichWe compared commercial kits for extraction of genomic DNA from the Gram-negative bacterium Klebsiella pneumoniae for subsequent Miseq sequencing. Purification of DNA was based on matrix binding (silica or anion exchange ...
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2016-07-28ZeitschriftenartikelComplete Genome Sequences of Two Methicillin-Sensitive Staphylococcus aureus Isolates Representing a Population Subset Highly Prevalent in Human Colonization Weber, Robert E.; Layer, Franziska; Fuchs, Stephan; Bender, Jennifer K.; Fiedler, Stefan; Werner, Guido; Strommenger, BirgitHere, we report the high-quality draft genome sequences of two methicillin-susceptible Staphylococcus aureus isolates, 08-02119 and 08-02300. Belonging to sequence type 582 (ST582) and ST7, both isolates are representatives ...
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2020-11-04ZeitschriftenartikelComputational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research Hufsky, Franziska; Lamkiewicz, Kevin; Almeida, Alexandre; Aouacheria, Abdel; Arighi, Cecilia; Bateman, Alex; Baumbach, Jan; Beerenwinkel, Niko; Brandt, Christian; Cacciabue, Marco; Chuguransky, Sara; Drechsel, Oliver; Finn, Robert D; Fritz, Adrian; Fuchs, Stephan; Hattab, Georges; Hauschild, Anne-Christin; Heider, Dominik; Hoffmann, Marie; Hölzer, Martin; Hoops, Stefan; Kaderali, Lars; Kalvari, Ioanna; von Kleist, Max; Kmiecinski, Renó; Kühnert, Denise; Lasso, Gorka; Libin, Pieter; List, Markus; Löchel, Hannah F.; Martin, Maria J.; Martin, Roman; Matschinske, Julian; McHardy, Alice C.; Mendes, Pedro; Mistry, Jaina; Navratil, Vincent; Nawrocki, Eric P.; O'Toole, Áine Niamh; Ontiveros-Palacios, Nancy; Petrov, Anton I; Rangel-Pineros, Guillermo; Redaschi, Nicole; Reimering, Susanne; Reinert, Knut; Reyes, Alejandro; RIchardson, Lorna; Robertson, David L.; Sadegh, Sepideh; Singer, Joshua B.; Theys, Kristof; Upton, Chris; Welzel, Marius; Williams, Lowri; Marz, ManjaSARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. ...
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2016-06-27ZeitschriftenartikelCosts of life - Dynamics of the protein inventory of Staphylococcus aureus during anaerobiosis Zühlke, Daniela; Dörries, Kirsten; Bernhardt, Jörg; Maaß, Sandra; Muntel, Jan; Liebscher, Volkmar; Pané-Farré, Jan; Riedel, Katharina; Lalk, Michael; Völker, Uwe; Engelmann, Susanne; Becher, Dörte; Fuchs, Stephan; Hecker, MichaelAbsolute protein quantification was applied to follow the dynamics of the cytoplasmic proteome of Staphylococcus aureus in response to long-term oxygen starvation. For 1,168 proteins, the majority of all expressed proteins, ...
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2018-04-09ZeitschriftenartikelEffektives Management eines Ausbruchs mit multiresistenten Klebsiella pneumoniae in der Neurorehabilitation Dohle, Christian; Korr, Gerit; Friedrichs, Michael; Kullmann, Volker; Tung, Mei-Lin; Kaase, Martin; Rüssmann, Holger; Sissolak, Dagmar; Werber, Dirk; Becker, Laura; Fuchs, Stephan; Pfeifer, Yvonne; Semmler, Torsten; Widders, Gudrun; Eckmanns, Tim; Werner, Guido; Zill, Edith; Haller, SebastianHintergrund Neben Akutkliniken sind auch Rehabilitationskliniken zunehmend von der Problematik der multiresistenten Erreger betroffen. Lange Verweildauern und hohe Behandlungsintensitäten stellen dabei besondere ...
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2021-01-19ZeitschriftenartikelGenome-Based Analyses of Fitness Effects and Compensatory Changes Associated with Acquisition of blaCMY-, blaCTX-M-, and blaOXA-48/VIM-1-Containing Plasmids in Escherichia coli Pietsch, Michael; Pfeifer, Yvonne; Fuchs, Stephan; Werner, GuidoBackground: Resistance plasmids are under selective conditions beneficial for the bacterial host, but in the absence of selective pressure, this carriage may cause fitness costs. Compensation of this fitness burden is ...
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2018-05-02ZeitschriftenartikelGenome-based analysis of Carbapenemase-producing Klebsiella pneumoniae isolates from German hospital patients, 2008-2014 Becker, Laura; Kaase, Martin; Pfeifer, Yvonne; Fuchs, Stephan; Reuss, Annicka; von Laer, Anja; Abu Sin, Muna; Korte-Berwanger, Miriam; Gatermann, Sören; Werner, GuidoBackground By using whole genome sequence data we aimed at describing a population snapshot of carbapenemase-producing K. pneumoniae isolated from hospitalized patients in Germany between 2008 and 2014. Methods We ...
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2021-02-15ZeitschriftenartikelGenome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in Staphylococcus aureus Weber, Robert E.; Fuchs, Stephan; Layer, Franziska; Sommer, Anna; Bender, Jennifer K.; Thürmer, Andrea; Werner, Guido; Strommenger, BirgitBackground: As next generation sequencing (NGS) technologies have experienced a rapid development over the last decade, the investigation of the bacterial genetic architecture reveals a high potential to dissect causal ...
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2018-02-15ZeitschriftenartikelHigh-Throughput Quantification of Bacterial-Cell Interactions Using Virtual Colony Counts Hoffmann, Stefanie; Walter, Steffi; Blume, Anne-Kathrin; Fuchs, Stephan; Schmidt, Christiane; Scholz, Annemarie; Gerlach, Roman G.The quantification of bacteria in cell culture infection models is of paramount importance for the characterization of host-pathogen interactions and pathogenicity factors involved. The standard to enumerate bacteria in ...
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2019-12-17ZeitschriftenartikelIS26-Mediated Transfer of blaNDM–1 as the Main Route of Resistance Transmission During a Polyclonal, Multispecies Outbreak in a German Hospital Weber, Robert E.; Pietsch, Michael; Frühauf, Andre; Pfeifer, Yvonne; Martin, Maria; Luft, Dirk; Gatermann, Sören; Pfennigwerth, Niels; Kaase, Martin; Werner, Guido; Fuchs, StephanOne of the most demanding challenges in infection control is the worldwide dissemination of multidrug-resistant (MDR) bacteria in clinical settings. Especially the increasing prevalence of carbapenemase producing Gram-negative ...
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2019-08-26ZeitschriftenartikelMetaproteomics analysis of microbial diversity of human saliva and tongue dorsum in young healthy individuals Rabe, Alexander; Salazar, Manuela Gesell; Michalik, Stephan; Fuchs, Stephan; Welk, Alexander; Kocher, Thomas; Völker, UweBackground: The human oral microbiome influences initiation or progression of diseases like caries or periodontitis. Metaproteomics approaches enable the simultaneous investigation of microbial and host proteins and their ...
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2017-05-25ZeitschriftenartikelMicrobial functionality as affected by experimental warming of a temperate mountain forest soil—A metaproteomics survey Liu, Dong; Keiblinger, Katharina M.; Schindlbacher, Andreas; Wegner, Uwe; Sun, Hanyin; Fuchs, Stephan; Lassek, Christian; Riedel, Katharina; Zechmeister-Boltenstern, SophieSoil microbes play an important role in terrestrial carbon (C) cycling, but their functional response to global warming remains yet unclear. Soil metaproteomics has the potential to contribute to a better understanding of ...
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2021-09-06ZeitschriftenartikelMutations in the gdpP gene are a clinically relevant mechanism for β-lactam resistance in meticillin-resistant Staphylococcus aureus lacking mec determinants Sommer, Anna; Fuchs, Stephan; Layer, Franziska; Schaudinn, Christoph; Weber, Robert E.; Richard, Hugues; Erdmann, Mareike B.; Laue, Michael; Schuster, Christopher F.; Werner, Guido; Strommenger, BirgitIn Staphylococcus aureus, resistance to β-lactamase stable β-lactam antibiotics is mediated by the penicillinbinding protein 2a, encoded by mecA or by its homologues mecB or mecC. However, a substantial number of ...
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2019-07-11ZeitschriftenartikelPadR-type repressors controlling production of a non-canonical FtsW/RodA homologue and other trans-membrane proteins Hauf, Samuel; Möller, Lars; Fuchs, Stephan; Halbedel, SvenThe Gram-positive bacterium Listeria monocytogenes occurs ubiquitously in the environment and infects humans upon ingestion. It encodes four PadR-like repressors, out of which LftR has been characterized previously and was ...
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2016-02-23ZeitschriftenartikelPopulation structure and acquisition of the vanB resistance determinant in German clinical isolates of Enterococcus faecium ST192 Bender, Jennifer K.; Kalmbach, Alexander; Fleige, Carola; Klare, Ingo; Fuchs, Stephan; Werner, GuidoIn the context of the global action plan to reduce the dissemination of antibiotic resistances it is of utmost importance to understand the population structure of resistant endemic bacterial lineages and to elucidate how ...
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2017-10-09ZeitschriftenartikelRelatedness of wildlife and livestock avian isolates of the nosocomial pathogen Acinetobacter baumannii to lineages spread in hospitals worldwide Wilharm, Gottfried; Skiebe, Evelyn; Higgins, Paul G.; Poppel, Marie T.; Blaschke, Ulrike; Leser, Sarah; Heider, Christine; Heindorf, Magdalena; Brauner, Paul; Jäckel, Udo; Böhland, Karin; Cuny, Christiane; Lopinska, Andzelina; Kaminski, Piotr; Kasprzak, Mariusz; Bochenski, Marcin; Ciebiera, Olaf; Tobolka, Marcin; Layer, Franziska; Bender, Jennifer K.; Fuchs, Stephan; Semmler, Torsten; Pfeifer, Yvonne; Jerzak, LeszekThe natural habitats and potential reservoirs of the nosocomial pathogen Acinetobacter baumannii are poorly defined. Here, we put forth and tested the hypothesis of avian reservoirs of A. baumannii. We screened tracheal ...