- edoc-Server Home
- Artikel in Fachzeitschriften
- Browsing Artikel in Fachzeitschriften by Author
Browsing Artikel in Fachzeitschriften by Author "Denner, Joachim"
Now showing items 1-20 of 67
-
2019-12-29ZeitschriftenartikelA Comprehensive Strategy for Screening for Xenotransplantation-Relevant Viruses in a Second Isolated Population of Göttingen Minipigs Krüger, Luise; Kristiansen, Yannick; Reuber, Emelie; Möller, Lars; Laue, Michael; Reimer, Christian; Denner, JoachimXenotransplantation using pig tissues and organs is under development in order to alleviate the increasing shortage of human transplants. Since xenotransplantation may be associated with the transmission of porcine ...
-
2018-07-12ZeitschriftenartikelAbsence of IL-10 production by human PBMCs co-cultivated with human cells expressing or secreting retroviral immunosuppressive domains Ivanusic, Daniel; Pietsch, Heiko; König, Jasper; Denner, JoachimImmunosuppression by retroviruses including the human immunodeficiency virus—1 (HIV-1) is well known, however the mechanisms how retroviruses induce this immunosuppression is not fully investigated. It was shown that ...
-
2011-01-01ZeitschriftenartikelAbsence of infection in pigs inoculated with high-titre recombinant PERV-A/C Kaulitz, Danny; Mihica, Debora; Plesker, Roland; Geissler, Anne; Tönjes, Ralf R.; Denner, JoachimPorcine endogenous retroviruses (PERVs) represent a risk for xenotransplantation using pig cells or organs since they are integrated in the genome of all pigs and infect human cells in vitro. Recombinants between PERV-A ...
-
2016-08-31ZeitschriftenartikelActive Replication of Porcine Cytomegalovirus (PCMV) Following Transplantation of a Pig Heart into a Baboon despite Undetected Virus in the Donor Pig Morozov, Vladimir A.; Abicht, Jan-Michael; Reichart, Bruno; Mayr, Tanja; Guethoff, Sonja; Denner, JoachimViral zoonoses may represent a serious problem when xenotransplantation using pig cells, tissues, and organs will be performed. Recently we reported multiorgan failure, mainly liver failure, in a baboon (Papio anubis) ...
-
2017-10-28ZeitschriftenartikelAntibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6) Fiebig, Uwe; Holzer, Angela; Ivanusic, Daniel; Plotzki, Elena; Hengel, Hartmut; Neipel, Frank; Denner, JoachimPorcine cytomegalovirus (PCMV) infection is widely prevalent among pigs, and PCMV is one of the viruses which may be transmitted during xenotransplantation using pig cells, tissues, or organs. While human cytomegalovirus ...
-
2017-03-10ZeitschriftenartikelAntigenic and immunosuppressive properties of a trimeric recombinant transmembrane envelope protein gp41 of HIV-1 Mühle, Michael; Lehmann, Melissa; Hoffmann, Kerstin; Stern, Daniel; Kroniger, Tobias; Luttmann, Werner; Denner, JoachimThe transmembrane envelope (TM) protein gp41 of the human immunodeficiency virus—1 (HIV-1) plays an important role during virus infection inducing the fusion of the viral and cellular membranes. In addition, there are ...
-
2003-10-01ZeitschriftenartikelBericht über das 6.Minisymposium Xenotransplantation am Robert Koch-Institut in Berlin im Mai 2003 Denner, Joachim
-
2004-09-20ZeitschriftenartikelBericht über das 7. Minisymposium Xenotransplantation am Robert Koch-Institut in Berlin im Juni 2004 Denner, Joachim
-
2001-11-01ZeitschriftenartikelBericht über das vierte Minisymposium Xenotransplantation am Robert Koch- Institut in Berlin im Mai 2001 Denner, Joachim
-
2017-08-08ZeitschriftenartikelCan Antiretroviral Drugs Be Used to Treat Porcine Endogenous Retrovirus (PERV) Infection after Xenotransplantation? Denner, JoachimPorcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs; they are released as infectious particles, and under certain conditions they can infect human cells. Therefore, they represent a risk when ...
-
2010-04-01ZeitschriftenartikelCharacterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C. Karlas, Alexander; Irgang, Markus; Votteler, Jörg; Specke, Volker; Ozel, Mushin; Kurth, Reinhard; Denner, JoachimBackground: Porcine endogenous retroviruses (PERVs) pose a potential risk for xenotransplantation using pig cells, tissues or organs. A special threat comes from viruses generated by recombination between human-tropic ...
-
2019-11-30ZeitschriftenartikelComparative Analysis of Roseoloviruses in Humans, Pigs, Mice, and Other Species Denner, JoachimViruses of the genus Roseolovirus belong to the subfamily Betaherpesvirinae, family Herpesviridae. Roseoloviruses have been studied in humans, mice and pigs, but they are likely also present in other species. This is the ...
-
2020-04-08ZeitschriftenartikelCopy Number and Prevalence of Porcine Endogenous Retroviruses (PERVs) in German Wild Boars Krüger, Luise; Stillfried, Milena; Prinz, Carolin; Schröder, Vanessa; Neubert, Lena Katharina; Denner, JoachimPorcine endogenous retroviruses (PERVs) are integrated in the genome of pigs and are transmitted like cellular genes from parents to the offspring. Whereas PERV-A and PERV-B are present in all pigs, PERV-C was found to be ...
-
2015-04-24ZeitschriftenartikelCytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN) Semaan, Marwan; Ivanusic, Daniel; Denner, JoachimXenotransplantation has been proposed as a solution to the shortage of suitable human donors for transplantation and pigs are currently favoured as donor animals. However, xenotransplantation may be associated with the ...
-
2010-03-10ZeitschriftenartikelDetection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation Denner, JoachimXMRV (xenotropic murine leukaemia virus-related virus) is a gammaretrovirus that has been detected in human patients with prostate carcinoma, chronic fatigue syndrome (CFS) and also in a small percentage of clinically ...
-
2019-02-22ZeitschriftenartikelDetection of PCV3 in German wild boars Prinz, Carolin; Stillfried, Milena; Neubert, Lena Katharina; Denner, JoachimBackground Porcine circovirus 3 is a newly described circovirus circulating worldwide. PCV3 may play an etiologic role in different pig diseases. Two different genotypes of PCV3 were described, PCV3a and PCV3b. In order ...
-
2011-04-29ZeitschriftenartikelDevelopment of sensitive methods for detection of porcine endogenous retrovirus-C (PERV-C) in the genome of pigs Kaulitz, Danny; Mihica, Debora; Dorna, Jens; Costa, Michael Rodrigues; Petersen, Björn; Niemann, Heiner; Tönjes, Ralf R.; Denner, JoachimPorcine endogenous retroviruses (PERV) represent a risk for xenotransplantation using pig cells, tissues or organs. PERV-A and PERV-B are present in the genome of all pigs and both infect human cells in vitro. PERV-C infects ...
-
2009-04-22ZeitschriftenartikelDistribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation Dieckhoff, Britta; Kessler, Barbara; Jobst, Danny; Kues, Wilfried A.; Petersen, Björn; Pfeifer, Alexander; Kurth, Reinhard; Niemann, Heiner; Wolf, Eckhard; Denner, JoachimBackground: Multi-transgenic pigs produced for use in xenotransplantation have to be screened for the presence and expression of porcine endogenous retroviruses (PERV) to select animals with low PERV load. The production ...
-
2018-02-06ZeitschriftenartikelDistribution of Porcine Cytomegalovirus in Infected Donor Pigs and in Baboon Recipients of Pig Heart Transplantation Fiebig, Uwe; Abicht, Jan-Michael; Mayr, Tanja; Längin, Matthias; Bähr, Andrea; Guethoff, Sonja; Falkenau, Almuth; Wolf, Eckhard; Reichart, Bruno; Shibahara, Tomoyuki; Denner, JoachimThe porcine cytomegalovirus (PCMV) is a herpesvirus that may pose a risk for xenotransplantation using pig cells, tissues, or organs. Here, three orthotopic pig heart transplantations into baboons were studied. To detect ...
-
2017-10-18ZeitschriftenartikelEasy and cost-effective stable positioning of suspension cells during live-cell imaging Ivanusic, Daniel; Madela, Kazimierz; Denner, JoachimDynamic processes of cells can be best monitored when living cells are analyzed by imaging. While it is easy to observe adherent living cells it has been extremely challenging to analyze suspension cells. This cell type ...