Auflistung Artikel in Fachzeitschriften nach Schlagwort "Immediate-Early Proteins/genetics"
Anzeige der Publikationen 1-4 von 4
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2011-07-27ZeitschriftenartikelConstruction of a lytically replicating Kaposi's sarcoma-associated herpesvirus (KSHV) Karposi's sarcoma-associated herpesvirus (KSHV) is found predominantly in a latent state in most cell types, impeding investigations of the lytic replication cycle. Here, we engineered the cloned KSHV genome, bacterial ...
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2009-11-18ZeitschriftenartikelDeletion of the rat cytomegalovirus immediate-early 1 gene results in a virus capable of establishing latency, but with lower levels of acute virus replication and latency that compromise reactivation efficiency The immediate-early 1 (IE1) and IE2 proteins encoded by the major immediate-early (MIE) transcription unit of cytomegaloviruses are thought to play key roles in the switch between latent- and lytic-cycle infection. Whilst ...
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2009-11-18ZeitschriftenartikelDeletion of the rat cytomegalovirus immediate-early 1 gene results in a virus capable of establishing latency, but with lower levels of acute virus replication and latency that compromise reactivation efficiency. The IE1 and IE2 proteins encoded by the major immediate-early (MIE) transcription unit of cytomegaloviruses are thought to play key roles in the switch between latent and lytic cycle infection. Whilst IE2 is essential for ...
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2010-06-02ZeitschriftenartikelMutations in the M112/M113-coding region facilitate murine cytomegalovirus replication in human cells. Cytomegaloviruses, representatives of the Betaherpesvirinae, cause opportunistic infections in immunocompromised hosts. They infect various cells and tissues in their natural host but are highly species specific. For ...