2009-10-27Zeitschriftenartikel
Activation of the Antiviral Kinase PKR and Viral Countermeasures
Dauber, Bianca; Wolff, Thorsten
The interferon-induced double-stranded (ds)RNA-dependent protein kinase (PKR) limits viral replication by an eIF2-mediated block of translation. Although many negative-strand RNA viruses activate PKR, the responsible ...