2022-02-02Zeitschriftenartikel
Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance
Gömer, André; Brown, Richard J. P.; Pfaender, Stephanie; Deterding, Katja; Reuter, Gábor; Orton, Richard; Seitz, Stefan; Bock, C.- Thomas; Cavalleri, Jessika M. V.; Pietschmann, Thomas; Wedemeyer, Heiner; Steinmann, Eike; Todt, Daniel
Even 30 years after the discovery of the hepatitis C virus (HCV) in humans there is still no vaccine available. Reasons for this include the high mutation rate of HCV, which allows the virus to escape immune recognition ...