2011-05-04Zeitschriftenartikel
Fosmidomycin Uptake into Plasmodium and Babesia-Infected Erythrocytes Is Facilitated by Parasite-Induced New Permeability Pathways
Baumeister, Stefan; Wiesner, Jochen; Reichenberg, Armin; Hintz, Martin; Bietz, Sven; Harb, Omar S.; Roos, David S.; Kordes, Maximilian; Friesen, Johannes; Matuschewski, Kai; Lingelbach, Klaus; Jomaa, Hassan; Seeber, Frank
Background: Highly charged compounds typically suffer from low membrane permeability and thus are generally regarded as sub-optimal drug candidates. Nonetheless, the highly charged drug fosmidomycin and its more active ...