2010-08-04Zeitschriftenartikel
Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein
Zielecki, Florian; Semmler, Ilia; Kalthoff, Donata; Voss, Daniel; Mauel, Susanne; Gruber, Achim D.; Beer, Martin; Wolff, Thorsten
We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses ...
