2021-02-09Zeitschriftenartikel
Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection
Cingöz, Oya; Arnow, Nicolas D.; Torrents, Mireia Puig; Bannert, Norbert
Background
The genomes of HIV-2 and some SIV strains contain the accessory gene vpx, which carries out several functions during infection, including the downregulation of SAMHD1. Vpx is also commonly used in experiments ...