Auflistung Artikel in Fachzeitschriften nach Schlagwort "PrPSc Proteins/metabolism"
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2007-05-25ZeitschriftenartikelAccumulation of Pathological Prion Protein PrPSc in the Skin of Animals with Experimental and Natural Scrapie Prion infectivity and its molecular marker, the pathological prion protein PrPSc, accumulate in the central nervous system and often also in lymphoid tissue of animals or humans affected by transmissible spongiform ...
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2008-09-29ZeitschriftenartikelFaecal shedding, alimentary clearance and intestinal spread of prions in hamsters fed with scrapie Shedding of prions via faeces may be involved in the transmission of contagious prion diseases. Here, we fed hamsters 10mg of 263K scrapie brain homogenate and examined the faecal excretion of disease-associated prion ...
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2007-09-25ZeitschriftenartikelRelevance of the regional lymph node in scrapie pathogenesis after peripheral infection of hamsters Background: The exact role of the lymphoreticular system in the spread of peripheral prion infections to the central nervous system still needs further elucidation. Against this background, the influence of the regional ...
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2013-03-11ZeitschriftenartikelTowards further reduction and replacement of animal bioassays in prion research by cell and protein misfolding cyclic amplification assays Laboratory animals have long since been used extensively in bioassays for prions in order to quantify, usually in terms of median infective doses [ID50], how infectious these pathogens are in vivo. The identification of ...