Browsing Artikel in Fachzeitschriften by Subject "Protein Binding"
Now showing items 1-9 of 9
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2013-06-12ZeitschriftenartikelAntibody Responses in Humans Infected with Newly Emerging Strains of West Nile Virus in Europe Infection with West Nile Virus (WNV) affects an increasing number of countries worldwide. Although most human infections result in no or mild flu-like symptoms, the elderly and those with a weakened immune system are at ...
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2010-01-20ZeitschriftenartikelCRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses The non-structural protein 1 (A/NS1) of influenza A viruses (IAV) harbours several src-homology domain (SH) binding motifs that are required for interaction with cellular proteins. The SH3 binding motif at aa212-217 [PPLPPK] ...
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2011-04-06ZeitschriftenartikelCytomegalovirus e127 protein interacts with the inhibitory CD200 receptor. CD200 is a cell surface glycoprotein that binds an inhibitory receptor (CD200R) on myeloid cells. CD200 orthologues are present in many species of virus, and we show that the rat cytomegalovirus CD200 orthologue (e127) is ...
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2015-04-24ZeitschriftenartikelCytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN) Xenotransplantation has been proposed as a solution to the shortage of suitable human donors for transplantation and pigs are currently favoured as donor animals. However, xenotransplantation may be associated with the ...
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2009-04-24ZeitschriftenartikelExploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release Background: The ALG2-interacting protein X (ALIX)/AIP1 is an adaptor protein with multiple functions in intracellular protein trafficking that plays a central role in the biogenesis of enveloped viruses. The ubiquitin ...
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2015-02-06ZeitschriftenartikelIsolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype Botulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed ...
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2011-06-28ZeitschriftenartikelMolecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site The protein machinery of neurotransmitter exocytosis requires efficient orchestration in space and time, for speed and precision of neurotransmission and also for synaptic ontogeny and plasticity. However, its spatial ...
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2010-08-11ZeitschriftenartikelMumps virus small hydrophobic protein targets ataxin-1 ubiquitin-like interacting protein (ubiquilin 4) The small hydrophobic (SH) protein of mumps virus has been reported to interfere with innate immunity by inhibiting tumour necrosis factor alpha-mediated apoptosis. In a yeast two-hybrid screen we have identified the ...
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2007-07-05ZeitschriftenartikelThe Yersinia enterocolitica type three secretion chaperone SycO is integrated into the Yop regulatory network and binds to the Yop secretion protein YscM1 Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these ...