2012-07-27Zeitschriftenartikel
Zidovudine Exposure in HIV-1 Infected Tanzanian Women Increases Mitochondrial DNA Levels in Placenta and Umbilical Cords
Kunz, Andrea; Wurmb-Schwark, Nicole von; Sewangi, Julius; Ziske, Judith; Lau, Inga; Mbezi, Paulina; Theuring, Stefanie; Hauser, Andrea; Dugange, Festo; Katerna, Angela; Harms, Gundel
Background: Zidovudine (AZT) constitutes part of the recommended regimens for prevention and treatment of HIV-1 infection. At the same time, AZT as well as HIV-1 infection itself may induce mitochondrial damage. In this ...