Auflistung Artikel in Fachzeitschriften nach Schlagwort "immune response"

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2021-01-25Zeitschriftenartikel

Asymptomatic Infection of Marburg Virus Reservoir Bats Is Explained by a Strategy of Immunoprotective Disease Tolerance

Guito, Jonathan C.; Prescott, Joseph B.; Arnold, Catherine E.; Amman, Brian R.; Schuh, Amy J.; Spengler, Jessica R.; Sealy, Tara K.; Harmon, Jessica R.; Coleman-McCray, JoAnn D.; Kulcsar, Kirsten A.; Nagle, Elyse R.; Kumar, Raina; Palacios, Gustavo; Sanchez-Lockhart, Mariano; Towner, Jonathan S.

Marburg virus (MARV) is among the most virulent pathogens of primates, including humans. Contributors to severe MARV disease include immune response suppression and inflammatory gene dysregulation (“cytokine storm”), leading ...
2021-08-04Zeitschriftenartikel

Gene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients

Domaszewska, Teresa; Zyla, Joanna; Otto, Raik; Kaufmann, Stefan H.E.; Weiner, January

Group-aggregated responses to tuberculosis (TB) have been well characterized on a molecular level. However, human beings differ and individual responses to infection vary. We have combined a novel approach to individual ...
2024-11-10Zeitschriftenartikel

Immunomodulation and Protective Effects of Cordyceps militaris Extract Against Candida albicans Infection in Galleria mellonella Larvae

Eiamthaworn, Kiratiya; Holthaus, David; Suriyaprom, Sureeporn; Rickerts, Volker; Tragoolpua, Yingmanee

Cordyceps militaris-derived formulations are currently used for multiple purposes because of their medical properties, especially immune system modulation. This study analyzes the inhibitory effects of C. militaris aqueous ...
2024-01-08Zeitschriftenartikel

Peripheral immune responses to filoviruses in a reservoir versus spillover hosts reveal transcriptional correlates of disease

Guito, Jonathan C.; Arnold, Catherine E.; Schuh, Amy J.; Amman, Brian R.; Sealy, Tara K.; Spengler, Jessica R.; Harmon, Jessica R.; Coleman-McCray, Joann D.; Sanchez-Lockhart, Mariano; Palacios, Gustavo F.; Towner, Jonathan S.; Prescott, Joseph B.

Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no ...
2019-12-04Zeitschriftenartikel

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

Prescott, Joseph; Guito, Jonathan C.; Spengler, Jessica R.; Arnold, Catherine E.; Schuh, Amy J.; Amman, Brian R.; Sealy, Tara K.; Guerrero, Lisa W.; Palacios, Gustavo F.; Sanchez-Lockhart, Mariano; Albariño, Cesar G.; Towner, Jonathan S.

Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these ...