2021-03-18Zeitschriftenartikel
Non-Toxic Glycosylated Gold Nanoparticle-Amphotericin B Conjugates Reduce Biofilms and Intracellular Burden of Fungi and Parasites
Ghosh, Chandradhish; Varela-Aramburu, Silvia; Eldesouky, Hassan E.; Salehi Hossainy, Sharareh; Seleem, Mohamed N.; Aebischer, Toni; Seeberger, Peter H.
Infections by intracellular pathogens cause significant morbidity and mortality due to lack of efficient drug delivery. Amphotericin B, currently used to treat leishmaniasis and cryptococcosis, is very toxic and cannot ...