2023-11-21Zeitschriftenartikel
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier
Faist, Aileen; Schloer, Sebastian; Mecate-Zambrano, Angeles; Janowski, Josua; Schreiber, André; Boergeling, Yvonne; Conrad, Beate C. G.; Kumar, Sriram; Toebben, Leonie; Schughart, Klaus; Baumgardt, Morris; Kessler, Mirjana; Hoenzke, Katja; Hocke, Andreas; Trautmann, Marcel; Hartmann, Wolfgang; Kato, Hiroki; Rescher, Ursula; Christersson, Anmari; Kuehn, Joachim; Mellmann, Alexander; Wolff, Thorsten; Kuempers, Philip; Rovas, Alexandros; Wiewrodt, Rainer; Wiebe, Karsten; Barth, Peter; Ludwig, Stephan; Brunotte, Linda
SARS-CoV-2 is the causative agent of the immune response-driven disease COVID-19 for which new antiviral and anti-inflammatory treatments are urgently needed to reduce recovery time, risk of death and long COVID development. ...
