Artikel in Fachzeitschriften: Recent submissions
Now showing items 21-40 of 5418
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2023-06-07ZeitschriftenartikelEnhancing global preparedness during an ongoing pandemic from partial and noisy data As the coronavirus disease 2019 spread globally, emerging variants such as B.1.1.529 quickly became dominant worldwide. Sustained community transmission favors the proliferation of mutated sub-lineages with pandemic ...
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2023-10-14ZeitschriftenartikelDifferential Transcriptional Responses of Human Granulocytes to Fungal Infection with Candida albicans and Aspergillus fumigatus Neutrophils are critical phagocytic cells in innate immunity, playing a significant role in defending against invasive fungal pathogens. This study aimed to explore the transcriptional activation of human neutrophils in ...
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2022-11-16ZeitschriftenartikelReply to Martin and Dauby
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2023-03-28ZeitschriftenartikelHighly contiguous genomes of human clinical isolates of Giardia duodenalis reveal assemblage- and sub-assemblage-specific presence–absence variation in protein-coding genes Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a widespread gastrointestinal protozoan parasite with debated taxonomic status. Currently, eight distinct genetic sub-groups, termed assemblages A–H, are defined ...
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2023-06-15ZeitschriftenartikelFirst virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS) Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions ...
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2023-10-16ZeitschriftenartikelManaging and monitoring a pandemic: showcasing a practical approach for the genomic surveillance of SARS-CoV-2 With the rapidly growing amount of biological data, powerful but also flexible data management and visualization systems are of increasingly crucial importance. The COVID-19 pandemic has more than highlighted this need and ...
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2023-07-14ZeitschriftenartikelDevelopment of a prototype for high-frequency mental health surveillance in Germany: data infrastructure and statistical methods In the course of the COVID-19 pandemic and the implementation of associated non-pharmaceutical containment measures, the need for continuous monitoring of the mental health of populations became apparent. When the pandemic ...
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2023-04-21ZeitschriftenartikelThe Acinetobacter baumannii website (Ab-web): a multidisciplinary knowledge hub, communication platform, and workspace Acinetobacter baumannii is a Gram-negative bacterium increasingly implicated in hospital-acquired infections and outbreaks. Effective prevention and control of such infections are commonly challenged by the frequent emergence ...
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2023-08-22ZeitschriftenartikelNeighbourhood watch: genomic epidemiology of SARS-CoV-2 variants circulating in a German federal state, Mecklenburg-Western Pomerania, in 2020–2022 Global and even national genome surveillance approaches do not provide the resolution necessary for rapid and accurate direct response by local public health authorities. Hence, a regional network of microbiological ...
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2023-09-28ZeitschriftenartikelThe VBNC state: a fundamental survival strategy of Acinetobacter baumannii The viable but non-culturable (VBNC) state is a persistence strategy adopted by bacteria to withstand long-lasting periods of unfavorable conditions. VBNC cells evade classical detection methods and are therefore easily ...
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2023-02-10ZeitschriftenartikelDisease severity in hospitalized COVID-19 patients: comparing routine surveillance with cohort data from the LEOSS study in 2020 in Germany Introduction: Studies investigating risk factors for severe COVID-19 often lack information on the representativeness of the study population. Here, we investigate factors associated with severe COVID-19 and compare the ...
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2023-07-10ZeitschriftenartikelEx vivo infection model for Francisella using human lung tissue Introduction: Tularemia is mainly caused by Francisella tularensis (Ft) subsp. tularensis (Ftt) and Ft subsp. holarctica (Ftt) in humans and in more than 200 animal species including rabbits and hares. Human clinical ...
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2023-04-12ZeitschriftenartikelGerman Health Update Fokus (GEDA Fokus) among Residents with Croatian, Italian, Polish, Syrian, or Turkish Citizenship in Germany: Protocol for a Multilingual Mixed-Mode Interview Survey Background: Germany has a long history of migration. In 2020, more than 1 person in every 4 people had a statistically defined, so-called migration background in Germany, meaning that the person or at least one of their ...
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2023-10-11ZeitschriftenartikelVariantSurvival: a tool to identify genotype–treatment response Motivation: For a number of neurological diseases, such as Alzheimer’s disease, amyotrophic lateral sclerosis, and many others, certain genes are known to be involved in the disease mechanism. A common question is whether ...
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2023-10-26ZeitschriftenartikelThe type-2 Streptococcus canis M protein SCM-2 binds fibrinogen and facilitates antiphagocytic properties Streptococcus canis is a zoonotic agent that causes severe invasive diseases in domestic animals and humans, but little is known about its pathogenesis and virulence mechanisms so far. SCM, the M-like protein expressed by ...
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2023-02-06ZeitschriftenartikelVisualization of SARS-CoV-2 particles in naso/oropharyngeal swabs by thin section electron microscopy Background: SARS-CoV-2 replicates efficiently in the upper airways of humans and produces high loads of virus RNA and, at least in the initial phase after infection, many infectious virus particles. Studying virus ...
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2023-07-13ZeitschriftenartikelThe representative COVID-19 cohort Munich (KoCo19): from the beginning of the pandemic to the Delta virus variant Background: Population-based serological studies allow to estimate prevalence of SARS-CoV-2 infections despite a substantial number of mild or asymptomatic disease courses. This became even more relevant for decision ...
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2023-06-15ZeitschriftenartikelCould oral hygiene prevent cases of at-home-acquired Legionnaires’ disease? – Results of a comprehensive case–control study on infection sources, risk, and protective behaviors Introduction: The “LeTriWa study” on community-acquired cases of Legionnaires’ disease (LD) found that most cases likely acquired their infection at home (AHALD). However, which sources confer the infection is largely ...
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2023-05-29ZeitschriftenartikelHow valid is the 2- to 10-day incubation period for cases of Legionnaires’ disease?: A reappraisal in the context of the German LeTriWa study; Berlin, 2016–2020 The evidence for the incubation period of Legionnaires’ disease is based on data from a small number of outbreaks. An incubation period of 2–10 days is commonly used for the definition and investigation of cases. In the ...
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2023-11-10ZeitschriftenartikelS3-Leitlinie “Aktinische Keratose und Plattenepithelkarzinom der Haut“ – Update 2023, Teil 2: Epidemiologie und Ätiologie, Diagnostik, Therapie des invasiven Plattenepithelkarzinoms der Haut, Nachsorge und Prävention Aktinische Keratosen (AK) sind häufige Hautveränderungen bei hellhäutigen Menschen mit dem Potenzial, in ein kutanes Plattenepithelkarzinom (PEK) überzugehen. Beide Erkrankungen können mit erheblicher Morbidität verbunden ...