Auflistung Artikel in Fachzeitschriften nach Autor "Drosten, Christian"

Anzeige der Publikationen 1-20 von 30

2022-08-15Zeitschriftenartikel

Advancing Precision Vaccinology by Molecular and Genomic Surveillance of Severe Acute Respiratory Syndrome Coronavirus 2 in Germany, 2021

Oh, Djin-Ye; Hölzer, Martin; Paraskevopolou, Sofia; Tofimova, Maria; Hartkopf, Felix; Budt, Matthias; Wedde, Marianne; Richard, Hugues; Haldemann, Berit; Domaszewska, Teresa; Reiche, Janine; Keeren, Kathrin; Radonić, Aleksander; Ramos Calderón, Julia Patricia; Smith, Maureen Rebecca; Brinkmann, Annika; Trappe, Kathrin; Drechsel, Oliver; Klaper, Kathleen; Hein, Sascha; Hildt, Eberhardt; Haas, Walter; Calvignac-Spencer, Sébastien; Semmler, Torsten; Dürrwald, Ralf; Thürmer, Andrea; Drosten, Christian; Fuchs, Stephan; Kröger, Stefan; von Kleist, Max; Wolff, Thorsten; Integrated Molecular Surveillance for SARS-CoV-2 (IMS-SC2) Laboratory Network

Background Comprehensive pathogen genomic surveillance represents a powerful tool to complement and advance precision vaccinology. The emergence of the Alpha variant in December 2020 and the resulting efforts to track ...
2011-06-14Zeitschriftenartikel

An insect nidovirus emerging from a primary tropical rainforest.

Zirkel, Florian; Kurth, Andreas; Quan, Phenix-Lan; Briese, Thomas; Ellerbrok, Heinz; Pauli, Georg; Leendertz, Fabian; Lipkin, W. Ian; Ziebuhr, John; Drosten, Christian; Junglen, Sandra

Tropical rainforests show the highest level of terrestrial biodiversity and may be an important contributor to microbial diversity. Exploitation of these ecosystems may foster the emergence of novel pathogens. We report ...
2022-11-17Zeitschriftenartikel

Analysis of two choir outbreaks acting in concert to characterize long- range transmission risks through SARS-CoV-2, Berlin, Germany, 2020

Reichert, Felix; Stier, Oliver; Hartmann, Anne; Ruscher, Claudia; Brinkmann, Annika; Grossegesse, Marica; Neumann, Markus; Werber, Dirk; Hausner, Marius; Kunze, Mareike; Weiß, Bettina; Michel, Janine; Nitsche, Andreas; an der Heiden, Matthias; Kriegel, Martin; Corman, Victor Max; Jones, Terry Carleton; Drosten, Christian; Brommann, Tobias; Buchholz, Udo

Background Superspreading events are important drivers of the SARS-CoV-2 pandemic and long-range (LR) transmission is believed to play a major role. We investigated two choir outbreaks with different attack rates (AR) ...
2012-12-06Zeitschriftenartikel

Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections

Corman, V. M.; Müller, Marcel A.; Costabel, U.; Timm, J.; Binger, T.; Meyer, B.; Kreher, Petra; Lattwein, Erik; Eschbach-Bludau, M.; Nitsche, Andreas; Bleicker, T.; Landt, Olfert; Schweiger, Brunhilde; Drexler, Jan Felix; Osterhaus, A. D.; Haagmans, B. L.; Dittmer, U.; Bonin, F.; Wolff, Thorsten; Drosten, Christian

We present a rigorously validated and highly sensitive confirmatory real-time RT-PCR assay (1A assay) that can be used in combination with the previously reported upE assay. Two additional RT-PCR assays for sequencing are ...
2014-03-17Zeitschriftenartikel

Contact Investigation for Imported Case of Middle East Respiratory Syndrome, Germany

Reuss, Annicka; Litterst, Annette; Drosten, Christian; Seilmaier, Michael; Böhmer, Merle; Graf, Petra; Gold, Hermann; Wendtner, Clemens-Martin; Zanuzdana, Arina; Schaade, Lars; Haas, Walter; Buchholz, Udo

On March 19, 2013, a patient from United Arab Emirates who had severe respiratory infection was transferred to a hospital in Germany, 11 days after symptom onset. Infection with Middle East respiratory syndrome coronavirus ...
2013-02-21Zeitschriftenartikel

Contact investigation of a case of human novel coronavirus infection treated in a German hospital, October-November 2012

Buchholz, Udo; Müller, Marcel A.; Nitsche, Andreas; Sanewski, A.; Wevering, N.; Bauer-Balci, T.; Bonin, F.; Drosten, Christian; Schweiger, Brunhilde; Wolff, Thorsten; Muth, D.; Meyer, B.; Buda, Silke; Krause, Gérard; Schaade, Lars; Haas, Walter

On 24 October 2012, a patient with acute respiratory distress syndrome of unknown origin and symptom onset on 5 October was transferred from Qatar to a specialist lung clinic in Germany. Late diagnosis on 20 November of ...
2009-03-01Zeitschriftenartikel

Coordinated Implementation of Chikungunya Virus Reverse Transcription–PCR.

Panning, Marcus; Charrel, Remi N.; Mantke, Oliver Donoso; Landt, Olfert; Niedrig, Matthias; Drosten, Christian

A preformulated chikungunya virus real-time reverse transcription-PCR, quality-confirmed oligonucleotides, and noninfectious virus controls were distributed by the European Network for the Diagnosis of Imported Viral ...
2007-09-01Zeitschriftenartikel

Coronavirus Antibodies in African Bat Species

Müller, Marcel A.; Paweska, Janusz T.; Leman, Patricia A.; Drosten, Christian; Grywna, Klaus; Kemp, Alan; Braack, Leo; Sonnenberg, Karen; Niedrig, Matthias; Swanepoel, Robert

Asian bats have been identified as potential reservoir hosts of coronaviruses associated with severe acute respiratory syndrome (SARS-CoV). We detected antibody reactive with SARS-CoV antigen in 47 (6.7%) of 705 bat serum ...
2021-10-08Zeitschriftenartikel

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

Loyal, Lucie; Braun, Julian; Henze, Larissa; Kruse, Beate; Dingeldey, Manuela; Reimer, Ulf; Kern, Florian; Schwarz, Tatjana; Mangold, Maike; Unger, Clara; Dörfler, Friederike; Kadler, Shirin; Rosowski, Jennifer; Gürcan, Kübrah; Uyar-Aydin, Zehra; Frentsch, Marco; Kurth, Florian; Schnatbbaum, Karsten; Eckey, Maren; Hippenstiel, Stefan; Hocke, Andreas; Müller, Marcel A.; Sawitzki, Birgit; Miltenyi, Stefan; Paul, Friedemann; Mall, Marcus A.; Wenschuh, Holger; Voigt, Sebastian; Drosten, Christian; Lauster, Roland; Lachman, Nils; Sander, Leif-Erik; Corman, Victor M.; Röhmel, Jobst; Meyer-Arndt, Lil; Thiel, Andreas; Giesecke-Thiel, Claudia

INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection to respiratory failure. Severe disease courses are primarily associated with advanced age, immune dysfunctions, and comorbidities. ...
2021-06-08Zeitschriftenartikel

Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Schwarz, Tatjana; Tober-Lau, Pinkus; Hillus, David; Helbig, Elisa T.; Lippert, Lena J.; Thibeault, Charlotte; Koch, Willi; Landgraf, Irmgard; Michel, Janine; Bergfeld, Leon; Niemeyer, Daniela; Mühlemann, Barbara; Conrad, Claudia; Dang-Heine, Chantip; Kasper, Stefanie; Münn, Friederike; Kappert, Kai; Nitsche, Andreas; Tauber, Rudolf; Schmidt, Sein; Kopankiewicz, Piotr; Bias, Harald; Seybold, Joachim; von Kalle, Christof; Jones, Terry C.; Suttorp, Norbert; Drosten, Christian; Sander, Leif Erik; Corman, Victor M.; Kurth, Florian

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize ...
2021-11-04Zeitschriftenartikel

Establishment of a specimen panel for the decentralised technical evaluation of the sensitivity of 31 rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021

Puyskens, Andreas; Krause, Eva; Michel, Janine; Nübling, C. Micha; Scheiblauer, Heinrich; Bourquain, Daniel; Grossegesse, Marica; Valusenko, Roman; Corman, Victor M.; Drosten, Christian; Zwirglmaier, Katrin; Wölfel, Roman; Lange, Constanze; Kramer, Jan; Friesen, Johannes; Ignatius, Ralf; Müller, Michael; Schmidt-Chanasit, Jonas; Emmerich, Petra; Schaade, Lars; Nitsche, Andreas

Introduction The detection of SARS-CoV-2 with rapid diagnostic tests (RDT) has become an important tool to identify infected people and break infection chains. These RDT are usually based on antigen detection in a lateral ...
2018-05-17Zeitschriftenartikel

External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil

Fischer, Carlo; Pedroso, Celia; Mendrone, Alfredo; Filippis, Ana Maria Bispo de; Vallinoto, Antonio Carlos Rosário; Ribeiro, Bergmann Morais; Durigon, Edison Luiz; Marques, Ernesto T.A.; Campos, Gubio S.; Viana, Isabelle F.T.; Levi, José Eduardo; Scarpelli, Luciano Cesar; Nogueira, Mauricio Lacerda; Bastos, Michele de Souza; Souza, Nathalia C. Santiago; Khouri, Ricardo; Lira, Sanny M. Costa; Komninakis, Shirley Vasconcelos; Baronti, Cécile; Charrel, Rémi N.; Kümmerer, Beate M.; Drosten, Christian; Niedrig, Matthias; Netto, Eduardo Martins; Drexler, Jan Felix

We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied ...
2015-05-30Zeitschriftenartikel

First international external quality assessment of molecular diagnostics for Mers-CoV

Pas, Suzan D.; Patel, Pranav; Reusken, Chantal; Domingo, Cristina; Corman, Victor M.; Drosten, Christian; Dijkman, Ronald; Thiel, Volker; Nowotny, Norbert; Koopmans, Marion P.G.; Niedrig, Matthias

Background: Since the discovery of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, diagnostic protocols were quickly published and deployed globally. Objectives: We set out to assess the quality of ...
2021-09-07Zeitschriftenartikel

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

Schroeder, Simon; Christin, Mache; Kleine-Weber, Hannah; Corman, Victor M.; Muth, Doreen; Richter, Anja; Fatykhova, Diana; Memish, Ziad A.; Stanifer, Megan L.; Boulant, Steeve; Gultom, Mitra; Dijkman, Ronald; Eggeling, Stephan; Hocke, Andreas; Hippenstiel, Stefan; Thiel, Volker; Pöhlmann, Stefan; Wolff, Thorsten; Müller, Marcel A.; Drosten, Christian

Middle East respiratory syndrome coronavirus (MERS-CoV) is enzootic in dromedary camels across the Middle East and Africa. Virus-induced pneumonia in humans results from animal contact, with a potential for limited onward ...
2012-01-01Zeitschriftenartikel

Hantavirus in Bat, Sierra Leone

Weiss, Sabrina; Witkowski, Peter T.; Auste, Brita; Nowak, Kathrin; Weber, Natalie; Fahr, Jakob; Mombouli, Jean-Vivien; Wolfe, Nathan D.; Drexler, Jan Felix; Drosten, Christian; Klempa, Boris; Leendertz, Fabian; Krüger, Detlev H.
2010-01-15Zeitschriftenartikel

Human Coronavirus NL63 Open Reading Frame 3 encodes a virion-incorporated N-glycosylated membrane protein

Müller, Marcel A.; Hoek, Lia van der; Voss, Daniel; Bader, Oliver; Lehmann, Dörte; Schulz, Axel R.; Kallies, Stephan; Suliman, Tasnim; Fielding, Burtram C; Drosten, Christian; Niedrig, Matthias

Background: Human pathogenic coronavirus NL63 (hCoV-NL63) is a group 1 (alpha) coronavirus commonly associated with respiratory tract infections. In addition to known non-structural and structural proteins all coronaviruses ...
2018-06-27Zeitschriftenartikel

Human coronavirus OC43 outbreak in wild chimpanzees, Côte d´Ivoire, 2016

Patrono, Livia V.; Samuni, Liran; Corman, Victor M.; Nourifar, Leila; Röthemeier, Caroline; Wittig, Roman M.; Drosten, Christian; Calvignac-Spencer, Sébastien; Leendertz, Fabian H.
2023-04-02Zeitschriftenartikel

Monitoring the SARS-CoV-2 Pandemic: Prevalence of Antibodies in a Large, Repetitive Cross-Sectional Study of Blood Donors in Germany—Results from the SeBluCo Study 2020–2022

Offergeld, Ruth; Preußel, Karina; Zeiler, Thomas; Aurich, Konstanze; Baumann-Baretti, Barbara I.; Ciesek, Sandra; Corman, Victor M.; Dienst, Viktoria; Drosten, Christian; Görg, Siegfried; Greinacher, Andreas; Grossegesse, Marica; Haller, Sebastian; Heuft, Hans-Gert; Hofmann, Natalie; Horn, Peter A.; Houareau, Claudia; Gülec, Ilay; Jiménez Klingberg, Carlos Luis; Juhl, David; Lindemann, Monika; Martin, Silke; Neuhauser, Hannelore K.; Nitsche, Andreas; Ohme, Julia; Peine, Sven; Sachs, Ulrich J.; Schaade, Lars; Schäfer, Richard; Scheiblauer, Heinrich; Schlaud, Martin; Schmidt, Michael; Umhau, Markus; Vollmer, Tanja; Wagner, Franz F.; Wieler, Lothar H.; Wilking, Hendrik; Ziemann, Malte; Zimmermann, Marlow; an der Heiden, Matthias

SARS-CoV-2 serosurveillance is important to adapt infection control measures and estimate the degree of underreporting. Blood donor samples can be used as a proxy for the healthy adult population. In a repeated cross-sectional ...
2015-12-01Zeitschriftenartikel

No Evidence of Gouléako and Herbert Virus Infections in Pigs, Côte d’Ivoire and Ghana

Junglen, Sandra; Marklewitz, Marco; Zirkel, Florian; Wollny, Robert; Meyer, Benjamin; Heidemann, Hanna; Metzger, Sonja; Annan, Augustina; Dei, Dickson; Leendertz, Fabian H.; Oppong, Samuel; Drosten, Christian

A recent report suggested that 2 novel bunyaviruses discovered in insects in Côte d’Ivoire caused lethal disease in swine in South Korea. We conducted cell culture studies and tested serum from pigs exposed to mosquitoes ...
2020-11-30Zeitschriftenartikel

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

Meinhardt, Jenny; Radke, Josefine; Dittmayer, Carsten; Franz, Jonas; Thomas, Carolina; Mothes, Ronja; Laue, Michael; Schneider, Julia; Brünink, Sebastian; Greuel, Selina; Lehmann, Malte; Hassan, Olga; Aschman, Tom; Schumann, Elisa; Chua, Robert Lorenz; Conrad, Christian; Eils, Roland; Stenzel, Werner; Windgassen, Marc; Rößler, Larissa; Goebel, Hans-Hilmar; Gelderblom, Hans R.; Martin, Hubert; Nitsche, Andreas; Schulz-Schaeffer, Walter J.; Hakroush, Samy; Winkler, Martin S.; Tampe, Björn; Scheibe, Franziska; Körtvélyessy, Péter; Reinhold, Dirk; SIegmund, Britta; Kühl, Anja A.; Elezkurtaj, Sefer; Horst, David; Oesterhelweg, Lars; Tsokos, Michael; Ingold-Heppner, Barbara; Stadelmann, Christine; Drosten, Christian; Radbruch, Helena; Heppner, Frank L.; Corman, Victor Max

The newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a pandemic respiratory disease. Moreover, thromboembolic events throughout the body, including in the CNS, have been ...