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Auflistung Artikel in Fachzeitschriften nach Autor "Bock, Thomas"
Anzeige der Publikationen 1-20 von 27
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2014-08-14ZeitschriftenartikelA multicentre sero-behavioural survey for hepatitis B and C, HIV and HTLV among people who inject drugs in Germany using respondent driven sampling Zimmermann, Ruth; Marcus, Ulrich; Schäffer, Dirk; Leicht, Astrid; Wenz, Benjamin; Nielsen, Stine; Santos-Hövener, Claudia; Ross, Stefan; Stambouli, Oumaima; Ratsch, Boris A.; Bannert, Norbert; Bock, Thomas; Kücherer, Claudia; Hamouda, OsamahBackground: People who inject drugs are at high risk for hepatitis B, hepatitis C and HIV. HTLV was reported by neighboring countries to be prevalent in this population, but the situation for Germany is unclear. To ...
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2018-10-23ZeitschriftenartikelA new hepatitis E virus genotype 2 strain identified from an outbreak in Nigeria, 2017 Wang, Bo; Akanbi, Olusola Anuoluwapo; Harms, Dominik; Adesina, Olufisayo; Osundare, Folakemi Abiodun; Naidoo, Dhamari; Deveaux, Isabel; Ogundiran, Opeayo; Ugochukwu, Uzoma; Mba, Nwando; Ihekweazu, Chikwe; Bock, ThomasBackground: In 2017 the Nigerian Ministry of Health notified the World Health Organization (WHO) of an outbreak of hepatitis E located in the north-east region of the country with 146 cases with 2 deaths. The analysis ...
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2017-11-10ZeitschriftenartikelCapturing virus evolution by proteomic bioinformatics: Hunting for characteristic mutations in the hepatitis E virus genome Harms, Dominik; Wang, Bo; Papp, C. Patrick; Bock, Thomas
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2013-08-15ZeitschriftenartikelCo-infection of human parvovirus B19 with Plasmodium falciparum contributes to malaria disease severity in Gabonese patients Toan, Nguyen Linh; Sy, Bui Tien; Song, Le Huu; Luong, Hoang Van; Binh, Nguyen T.; Binh, Vu Q.; Kandolf, Reinhard; Velavan, Thirumalaisamy P.; Kremsner, Peter G.; Bock, ThomasBackground: High seroprevalence of parvovirus B19 (B19V) coinfection with Plasmodium falciparum has been previously reported. However, the impact of B19V-infection on the clinical course of malaria is still elusive. In ...
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2016-09-01ZeitschriftenartikelConcordance between self-reported and measured HIV and hepatitis C virus infection status among people who inject drugs in Germany Nielsen, Stine; Gassowski, Martyna; Wenz, Benjamin; Bannert, Norbert; Bock, Thomas; Kücherer, Claudia; Ross, Stefan; Bremer, Viviane; Marcus, Ulrich; Zimmermann, RuthBackground: People who inject drugs (PWID) are disproportionately affected by both HIV and hepatitis C infection (HCV). Awareness of infection status is essential to ensure linkage to appropriate healthcare for those ...
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2011-11-22ZeitschriftenartikelFicolin-2 Levels and FCN2 Haplotypes Influence Hepatitis B Infection Outcome in Vietnamese Patients. Tong, Hoang V.; Toan, Nguyen L.; Song, Le H.; Ouf, Eman Abou; Bock, Thomas; Kremsner, Peter G.; Kun, Jürgen F. J.; Velavan, T.P.Human Ficolin-2 (L-ficolins) encoded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity and is mainly expressed in the liver. Ficolin-2 serum levels and FCN2 single nucleotide polymorphisms ...
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2018-01-14ZeitschriftenartikelGenetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection Sy, Bui Tien; Hoan, Nghiem Xuan; Tong, Hoang Van; Meyer, Christian G.; Toan, Nguyen Linh; Song, Le Huu; Bock, Thomas; Velavan, Thirumalaisamy P.Aim: To investigate possible effects of IRF5 polymorphisms in the 3’ UTR region of the IFR5 locus on susceptibility to hepatitis B virus (HBV) infection and progression of liver diseases among clinically classified ...
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2018-05-23ZeitschriftenartikelHDV infection rates in northern Vietnam Binh, Mai Thanh; Hoan, Nghiem Xuan; Tong, Hoang Van; Giang, Dao Phuong; Sy, Bui Tien; Toan, Nguyen Linh; Song, Le Huu; Bang, Mai Hong; Wedemeyer, Heiner; Meyer, Christian G.; Kremsner, Peter G.; Bock, Thomas; Velavan, Thirumalaisamy P.Hepatitis D caused by the hepatitis delta virus (HDV) is a serious health problem in many regions of the world. A total of 546 HBV-infected patients were enrolled from 2013 to 2015 and classified clinically into the subgroups ...
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2014-09-01ZeitschriftenartikelHepatitis E in Deutschland – eine unterschätzte Infektionskrankheit Pischke, Sven; Behrendt, Patrick; Bock, Thomas; Jilg, Wolfgang; Manns, Michael P.; Wedemeyer, HeinerHintergrund: Mindestens 17 % der in Deutschland lebenden Bevölkerung haben eine Infektion mit dem Hepatitis-E-Virus (HEV) durchgemacht. Somit ist diese Infektion in Deutschland häufiger als bislang angenommen. Demgegenüber ...
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2016-08-06ZeitschriftenartikelHepatitis E Virus Mutations: Functional and Clinical Relevance Tong, Hoang van; Hoan, Nghiem Xuan; Wang, Bo; Wedemeyer, Heiner; Bock, Thomas; Velavan, Thirumalaisamy P.Hepatitis E virus (HEV) infection is a major cause of acute hepatitis and affects more than 20 million individuals, with three million symptomatic cases and 56,000 recognized HEV-related deaths worldwide. HEV is endemic ...
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2015-11-11ZeitschriftenartikelHepatitis E Virus Superinfection and Clinical Progression in Hepatitis B Patients Hoan, Nghiem Xuan; Tong, Hoang Van; Hecht, Nicole; Sy, Bui Tien; Marcinek, Patrick; Meyer, Christian G.; Song, Le Huu; Toan, Nguyen Linh; Kurreck, Jens; Kremsner, Peter G.; Bock, Thomas; Velavan, Thirumalaisamy P.Hepatitis E virus (HEV) infection may cause acute hepatitis and lead to hepatic failure in developing and developed countries. We studied HEV seroprevalences in patients with hepatitis B virus (HBV) infection to understand ...
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2015-11-10ZeitschriftenartikelHigh Prevalence and High Incidence of Coinfection with Hepatitis B, Hepatitis C, and Syphilis and Low Rate of Effective Vaccination against Hepatitis B in HIV-Positive Men Who Have Sex with Men with Known Date of HIV Seroconversion in Germany Jansen, Klaus; Thamm, Michael; Bock, Thomas; Scheufele, Ramona; Kücherer, Claudia; Muenstermann, Dieter; Hagedorn, Hans-Jochen; Jessen, Heiko; Dupke, Stephan; Hamouda, Osamah; Gunsenheimer-Bartmeyer, Barbara; Meixenberger, KarolinObjectives: Men who have sex with men (MSM) are at higher risk for coinfection with hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis than the general population. HIV infection and these coinfections ...
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2013-10-18ZeitschriftenartikelHigh Prevalence and Significance of Hepatitis D Virus Infection among Treatment-Naïve HBsAg-Positive Patients in Northern Vietnam Sy, Bui Tien; Ratsch, Boris A.; Toan, Nguyen Linh; Song, Le Huu; Wollboldt, Christian; Bryniok, Agnes; Nguyen, Hung Minh; Luong, Hoang Van; Velavan, Thirumalaisamy P.; Wedemeyer, Heiner; Kremsner, Peter G.; Bock, ThomasBackground: Hepatitis D virus (HDV) infection is considered to cause more severe hepatitis than hepatitis B virus (HBV) monoinfection. With more than 9.5 million HBV-infected people, Vietnam will face an enormous health ...
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2016-09-05ZeitschriftenartikelHigh variability of HIV and HCV seroprevalence and risk behaviours among people who inject drugs: results from a cross-sectional study using respondent-driven sampling in eight German cities (2011–14) Wenz, Benjamin; Nielsen, Stine; Gassowski, Martyna; Santos-Hövener, Claudia; Cai, Wei; Ross, Stefan; Bock, Thomas; Ratsch, Boris-Alexander; Kücherer, Claudia; Bannert, Norbert; Bremer, Viviane; Hamouda, Osamah; Marcus, Ulrich; Zimmermann, RuthBackground: People who inject drugs (PWID) are at increased risk of acquiring and transmitting HIV and Hepatitis C (HCV) due to sharing injection paraphernalia and unprotected sex. To generate seroprevalence data on HIV ...
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2017-05-18ZeitschriftenartikelIdentification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland Wang, Bo; Harms, Dominik; Hofmann, Jörg; Ciardo, Diana; Kneubühl, Agnes; Bock, ThomasHepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). ...
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2016-05-24ZeitschriftenartikelIn vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome Todt, Daniel; Gisa, Anett; Radonic, Aleksandar; Nitsche, Andreas; Behrendt, Patrick; Suneetha, Pothakamuri Venkata; Pischke, Sven; Bremer, Birgit; Brown, Richard J. P.; Manns, Michael P.; Cornberg, Markus; Bock, Thomas; Steinmann, Eike; Wedemeyer, HeinerObjective: Hepatitis E virus (HEV) infection can take chronic courses in immunocompromised patients potentially leading to liver cirrhosis and liver failure. Ribavirin (RBV) is currently the only treatment option for many ...
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2016-06-13ZeitschriftenartikelInfection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro Niendorf, Sandra; Klemm, Uwe; Marques, Andreas Mas; Bock, Thomas; Höhne, MarinaNorovirus infection is the main cause of epidemic non-bacterial gastroenteritis in humans. Although human norovirus (HuNoV) infection is self-limiting, it can persist for extended periods of time in immune deficient patients. ...
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2010-03-15ZeitschriftenartikelInterferon Beta Modulates Endothelial Damage in Patients with Cardiac Persistence of Human Parvovirus B19 Infection Schmidt-Lucke, Caroline; Spillmann, Frank; Bock, Thomas; Kühl, Uwe; Linthout, Sophie van; Schultheiss, Heinz-Peter; Tschöpe, CarstenBackground: In a phase 1 study, we investigated whether interferon beta reduced endothelial damage in patients with cardiac persistence of human parvovirus B19 (B19V) infection. Methods and results: In vitro, B19V infected ...
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2014-05-16ZeitschriftenartikelMolecular Epidemiology and Genotyping of Hepatitis B Virus of HBsAg-Positive Patients in Oman Baqlani, Said Ali Al; Sy, Bui Tien; Ratsch, Boris A.; Naamani, Khalid Al; Awaidy, Salah Al; Busaidy, Suleiman Al; Pauli, Georg; Bock, ThomasBackground: Hepatitis B virus (HBV) infection is a major global health burden with distinct geographic public health significance. Oman is a country with intermediate HBV carrier prevalence; however, little is known ...
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2016-01-14ZeitschriftenartikelMolecular epidemiology of hepatitis D virus circulating in Southwestern Nigeria Opaleye, Oluyinka Oladele; Japhet, Oluwatoyin Margaret; Adewumi, Olubusuyi Moses; Omoruyi, Ewean Chukwuma; Akanbi, Olusola Anuoluwapo; Oluremi, Adeolu Sunday; Wang, Bo; Tong, Hoang van; Velavan, Thirumalaisamy P.; Bock, ThomasBackground: Hepatitis B virus (HBV) and hepatitis D virus (HDV) infections are major public health problems in sub-Saharan Africa. Whereas it is known that HBV infection is endemic in Nigeria, there is only little data ...