Auflistung Artikel in Fachzeitschriften nach Schlagwort "Viral Load"
Anzeige der Publikationen 1-16 von 16
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2013-07-16ZeitschriftenartikelA Mouse Model for Human Norovirus Human noroviruses (HuNoVs) cause significant morbidity and mortality worldwide. However, despite substantial efforts, a small-animal model for HuNoV has not been described to date. Since "humanized" mice have been successfully ...
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2016-09-16ZeitschriftenartikelBrincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation Infections with adenovirus (AdV) and herpesviruses can result in considerable morbidity and mortality in pediatric hematopoietic stem cell transplant (SCT) recipients. Herpes simplex virus (HSV) reactivations are usually ...
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2011-07-27ZeitschriftenartikelConstruction of a lytically replicating Kaposi's sarcoma-associated herpesvirus (KSHV) Karposi's sarcoma-associated herpesvirus (KSHV) is found predominantly in a latent state in most cell types, impeding investigations of the lytic replication cycle. Here, we engineered the cloned KSHV genome, bacterial ...
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2009-07-01ZeitschriftenartikelCumulative HIV Viremia during Highly Active Antiretroviral Therapy Is a Strong Predictorof AIDS‐Related Lymphoma Background.AIDS‐related lymphoma contributes to significant morbidity and mortality among human immunodeficiency virus (HIV)–infected patients receiving highly active antiretroviral therapy (HAART). We assessed the predictive ...
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2009-04-22ZeitschriftenartikelDistribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation Background: Multi-transgenic pigs produced for use in xenotransplantation have to be screened for the presence and expression of porcine endogenous retroviruses (PERV) to select animals with low PERV load. The production ...
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2015-11-01ZeitschriftenartikelDoes rapid HIV disease progression prior to combination antiretroviral therapy hinder optimal CD4+ T-cell recovery once HIV-1 suppression is achieved? Objective: This article compares trends in CD4+ T-cell recovery and proportions achieving optimal restoration (≥500 cells/μl) after viral suppression following combination antiretroviral therapy (cART) initiation between ...
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2014-08-22ZeitschriftenartikelEstimating Trends in the Proportion of Transmitted and Acquired HIV Drug Resistance in a Long Term Observational Cohort in Germany Objective: We assessed trends in the proportion of transmitted (TDR) and acquired (ADR) HIV drug resistance and associated mutations between 2001 and 2011 in the German ClinSurv-HIV Drug Resistance Study. Method: ...
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2012-05-03ZeitschriftenartikelFirst International External Quality Assessment Study on Molecular and Serological Methods for Yellow Fever Diagnosis Objective: We describe an external quality assurance (EQA) study designed to assess the efficiency and accurateness of molecular and serological methods used by expert laboratories performing YF diagnosis. Study Design: ...
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2014-05-01ZeitschriftenartikelFirst Line Treatment Response in Patients with Transmitted HIV Drug Resistance and Well Defined Time Point of HIV Infection: Updated Results from the German HIV-1 Seroconverter Study Background: Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided ...
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2011-10-19ZeitschriftenartikelGrowth of influenza A virus is not impeded by simultaneous removal of the cholesterol binding and acylation sites in the M2 protein Influenza virus assembly and budding occur in the 'budozone', a coalesced raft domain in the plasma membrane. The viral transmembrane protein M2 is implicated in virus particle scission, the ultimate step in virus budding, ...
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2009-03-01ZeitschriftenartikelImmunogenicity and Safety of Yellow Fever Vaccination for 102 HIV‐Infected Patients Background: Yellow fever vaccine (17DV) has been investigated incompletely in human immunodeficiency virus (HIV)–infected patients, and adequate immunogenicity and safety are of concern in this population. Methods: In ...
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2015-05-01ZeitschriftenartikelLow-level Circulation of Enterovirus D68–Associated Acute Respiratory Infections, Germany, 2014 We used physician sentinel surveillance to identify 25 (7.7%) mild to severe infections with enterovirus D68 (EV-D68) in children and adults among 325 outpatients with acute respiratory infections in Germany during ...
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2010-06-02ZeitschriftenartikelMutations in the M112/M113-coding region facilitate murine cytomegalovirus replication in human cells. Cytomegaloviruses, representatives of the Betaherpesvirinae, cause opportunistic infections in immunocompromised hosts. They infect various cells and tissues in their natural host but are highly species specific. For ...
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2009-06-21ZeitschriftenartikelRole of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vector Background: We investigated the interplay between complement and antibodies upon priming with single-cycle replicating viral vectors (SCIV) encoding SIV antigens combined with Adeno5-SIV or SCIV pseudotyped with murine ...
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2012-10-03ZeitschriftenartikelTreatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...
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2013-07-30ZeitschriftenartikelVirologic and Immunologic Response to cART by HIV-1 Subtype in the CASCADE Collaboration Background: We aimed to compare rates of virologic response and CD4 changes after combination antiretroviral (cART) initiation in individuals infected with B and specific non-B HIV subtypes. Methods: Using CASCADE ...