Browsing Artikel in Fachzeitschriften by Subject "Sequence Analysis DNA/methods"
Now showing items 1-5 of 5
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2012-09-27ZeitschriftenartikelConfidence-based Somatic Mutation Evaluation and Prioritization Next generation sequencing (NGS) has enabled high throughput discovery of somatic mutations. Detection depends on experimental design, lab platforms, parameters and analysis algorithms. However, NGS-based somatic mutation ...
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2010-09-27ZeitschriftenartikelImproved Detection of Mutated Human Cytomegalovirus UL97 by Pyrosequencing Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ ...
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2013-03-26ZeitschriftenartikelMultiPSQ: A Software Solution for the Analysis of Diagnostic n-Plexed Pyrosequencing Reactions Background: Pyrosequencing can be applied for Single-Nucleotide-Polymorphism (SNP)-based pathogen typing or for providing sequence information of short DNA stretches. However, for some pathogens molecular typing cannot ...
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2011-07-20ZeitschriftenartikelProspective genomic characterization of the German enterohemorrhagic escherichia coli O104:H4 outbreak by rapid next generation sequencing technology. An ongoing outbreak of exceptionally virulent Shiga toxin (Stx)-producing Escherichia coli O104:H4 centered in Germany, has caused over 830 cases of hemolytic uremic syndrome (HUS) and 46 deaths since May 2011. Serotype ...
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2015-09-17ZeitschriftenartikelRAMBO-K: Rapid and Sensitive Removal of Background Sequences from Next Generation Sequencing Data Background: The assembly of viral or endosymbiont genomes from Next Generation Sequencing (NGS) data is often hampered by the predominant abundance of reads originating from the host organism. These reads increase the ...