2008-03-10Zeitschriftenartikel
Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs
Dieckhoff, Britta; Petersen, Björn; Kues, Wilfried A.; Kurth, Reinhard; Niemann, Heiner; Denner, Joachim
Background: Xenotransplantation using porcine cells, tissues or organs may be associated with the transmission of porcine endogenous retroviruses (PERVs). More than 50 viral copies have been identified in the pig genome ...