Browsing Artikel in Fachzeitschriften by Subject "Viral Nonstructural Proteins/genetics"
Now showing items 1-5 of 5
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2008-11-05ZeitschriftenartikelAnalysis of influenza B virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains Many proteins that function in the transcription, maturation, and export of metazoan mRNAs are concentrated in nuclear speckle domains, indicating that the compartment is important for gene expression. Here, we show that ...
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2009-06-12ZeitschriftenartikelInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR Activation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational ...
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2010-08-25ZeitschriftenartikelNS Reassortment of an H7-Type Highly Pathogenic Avian Influenza Virus Affects Its Propagation by Altering the Regulation of Viral RNA Production and Antiviral Host Response Highly pathogenic avian influenza viruses (HPAIV) with reassorted NS segments from H5- and H7-type avian virus strains placed in the genetic background of the A/FPV/Rostock/34 HPAIV (FPV; H7N1) were generated by reverse ...
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2015-03-13ZeitschriftenartikelSpot the Difference - Development of a Syndrome Based Protein Microarray for Specific Serological Detection of Multiple Flavivirus Infections in Travelers Background: The family Flaviviridae, genus Flavivirus, holds many of the world’s most prevalent arboviral diseases that are also considered the most important travel related arboviral infections. In most cases, flavivirus ...
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2010-08-04ZeitschriftenartikelVirulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses ...