2020-11-05Zeitschriftenartikel
Vaccine-induced CD8 T cells are redirected with peptide-MHC class I-IgG antibody fusion proteins to eliminate tumor cells in vivo
Fischer, Cornelia; Munks, Michael W.; Hill, Ann B.; Kroczek, Richard A.; Bissinger, Stafen; Brand, Verena; Schmittnaegel, Martina; Imhof-Jung, Sabine; Hoffmann, Eike; Herting, Frank; Klein, Christian; Knoetgen, Hendrik
Simulating a viral infection in tumor cells is an attractive concept to eliminate tumor cells. We previously reported the molecular design and the in vitro potency of recombinant monoclonal antibodies fused to a virus-derived ...