Artikel in Fachzeitschriften: Recent submissions
Now showing items 1481-1500 of 3922
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2018-04-03ZeitschriftenartikelMALDI Spectra Database for Rapid Discrimination and Subtyping of Mycobacterium kansasii Mycobacterium kansasii is an emerging non-tuberculous mycobacterial (NTM) pathogen capable of causing severe lung disease. Of the seven currently recognized M. kansasii genotypes (I-VII), genotypes I and II are most prevalent ...
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2018-03-22ZeitschriftenartikelPopulation Genomics of Francisella tularensis subsp. holarctica and its Implication on the Eco-Epidemiology of Tularemia in Switzerland Whole genome sequencing (WGS) methods provide new possibilities in the field of molecular epidemiology. This is particularly true for monomorphic organisms where the discriminatory power of traditional methods (e.g., ...
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2018-04-10ZeitschriftenartikelDisease detection, epidemiology and outbreak response: the digital future of public health practice Inequalities persist when it comes to the attention, resource allocation and political prioritization, and provision of appropriate, adequate, and timely health interventions to populations in need. Set against a complex ...
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2018-03-22ZeitschriftenartikelRapid Viral Diagnosis of Orthopoxviruses by Electron Microscopy: Optional or a Must? Diagnostic electron microscopy (DEM) was an essential component of viral diagnosis until the development of highly sensitive nucleic acid amplification techniques (NAT). The simple negative staining technique of DEM was ...
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2018-03-15ZeitschriftenartikelFind and treat or find and lose? Tuberculosis treatment outcomes among screened newly arrived asylum seekers in Germany 2002 to 2014 Background: Germany has a low tuberculosis (TB) incidence. A relevant and increasing proportion of TB cases is diagnosed among asylum seekers upon screening. Aim: We aimed to assess whether cases identified by screening ...
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2018-03-27ZeitschriftenartikelOccurrence and distribution of Giardia species in wild rodents in Germany Background: Giardiasis is an important gastrointestinal parasitic disease in humans and other mammals caused by the protozoan Giardia duodenalis. This species complex is represented by genetically distinct groups ...
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2018-03-27ZeitschriftenartikelPost-millennial trends of socioeconomic inequalities in chronic illness among adults in Germany Objective: Time trends in health inequalities have scarcely been studied in Germany as only few national data have been available. In this paper, we explore trends in socioeconomic inequalities in the prevalence of ...
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2018-05-17ZeitschriftenartikelExternal Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied ...
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2018-04-11ZeitschriftenartikelImpact of HIV knowledge and stigma on the uptake of HIV testing – Results from a community-based participatory research survey among migrants from sub-Saharan Africa in Germany Background: In 2015, 3,674 new HIV diagnoses were notified in Germany; 16% of those newly diagnosed cases originated from sub-Saharan Africa (sSA). One quarter of the newly diagnosed cases among migrants from sSA (MisSA) ...
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2018-04-02ZeitschriftenartikelWhy was PERV not transmitted during preclinical and clinical xenotransplantation trials and after inoculation of animals? Porcine endogenous retroviruses (PERVs) are present in the genome of all pigs, they infect certain human cells and therefore pose a special risk for xenotransplantation using pig cells, tissues and organs. Xenotransplantation ...
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2017-11-18ZeitschriftenartikelLegislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape Despite the increasing availability of direct-to-consumer (DTC) genetic testing, it is currently unclear how such services are regulated in Europe, due to the lack of EU or national legislation specifically addressing this ...
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2018-02-27ZeitschriftenartikelErfassung inzidenter kardiovaskulärer und metabolischer Erkrankungen in epidemiologischen Kohortenstudien in Deutschland Hintergrund: Kardiovaskuläre und metabolische Erkrankungen sind häufige Ursachen für Mortalität und Verlust von Lebensqualität in der deutschen Bevölkerung. Zur Erforschung von Risikofaktoren sind populationsbasierte ...
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2018-03-14ZeitschriftenartikelConstruction of a New Phage Integration Vector pFIV-Val for Use in Different Francisella Species We recently identified and described a putative prophage on the genomic island FhaGI-1 located within the genome of Francisella hispaniensis AS02-814 (F. tularensis subsp. novicida-like 3523). In this study, we constructed ...
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2018-03-20ZeitschriftenartikelPresence of Clostridium difficile in poultry and poultry meat in Egypt C. difficile has been recognized as a potential zoonotic agent encouraging investigations of C. difficile prevalence and ribotypes in animals. Here we report the prevalence and diversity of Egyptian C. difficile in I) ...
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2018-03-15ZeitschriftenartikelAnalysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA (Rv2043c) that encodes the pyrazinamidase enzyme responsible for conversion of pro-drug ...
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2018-03-07ZeitschriftenartikelHealth and health risk behaviour of adolescents—Differences according to family structure. Results of the German KiGGS cohort study Objective: This study’s aim was to investigate the association between family structure and different health-related outcomes in adolescence (self-rated health, emotional and behavioural problems, health-related quality ...
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2018-03-19ZeitschriftenartikelZelltherapeutika auf der Basis humaner pluripotenter Stammzellen: internationale klinische Studien im Überblick
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2018-02-27ZeitschriftenartikelHepatitis C virus: Morphogenesis, infection and therapy Hepatitis C virus (HCV) is a major cause of liver diseases including liver cirrhosis and hepatocellular carcinoma. Approximately 3% of the world population is infected with HCV. Thus, HCV infection is considered a public ...
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2018-02-20ZeitschriftenartikelStrain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier Background: Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the ...
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2018-03-05ZeitschriftenartikelIntravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA) Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference ...