Artikel in Fachzeitschriften: Neuzugänge
Anzeige der Publikationen 321-340 von 3855
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2021-03-24ZeitschriftenartikelComparative in silico genome analysis of Clostridium perfringens unravels stable phylogroups with different genome characteristics and pathogenic potential Clostridium perfringens causes a plethora of devastating infections, with toxin production being the underlying mechanism of pathogenicity in various hosts. Genomic analyses of 206 public-available C. perfringens strains´ ...
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2021-04-22ZeitschriftenartikelGenome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease Objective Haemorrhoidal disease (HEM) affects a large and silently suffering fraction of the population but its aetiology, including suspected genetic predisposition, is poorly understood. We report the first genome-wide ...
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2021-07-07ZeitschriftenartikelSafety and immunogenicity of ChAd63-KH vaccine in post-kala-azar dermal leishmaniasis patients in Sudan Post-kala-azar dermal leishmaniasis (PKDL) is a chronic, stigmatizing skin condition occurring frequently after apparent clinical cure from visceral leishmaniasis. Given an urgent need for new treatments, we conducted a ...
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2021-03-05ZeitschriftenartikelBurden of Disease Methods: A Guide to Calculate COVID-19 Disability-Adjusted Life Years Background To date, most efforts to understand the comparative population health impact of COVID-19 have been made using mortality-based metrics [1,2]. This has intensified discussion over methodological choices; in ...
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2021-06-15ZeitschriftenartikelAssessing conservation of alternative splicing with evolutionary splicing graphs Understanding how protein function has evolved and diversified is of great importance for human genetics and medicine. Here, we tackle the problem of describing the whole transcript variability observed in several species ...
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2021-08-11ZeitschriftenartikelChanges in Alcohol and Tobacco Consumption in Kupferzell (Baden-Württemberg) During the Period of COVID-19 Pandemic Restrictions
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2021-09-19ZeitschriftenartikelTherapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. ...
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2021-09-09ZeitschriftenartikelA year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood. In this study, we describe the genomic ...
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2021-08-09ZeitschriftenartikelOngoing High Incidence and Case-Fatality Rates for Invasive Listeriosis, Germany, 2010–2019 We used 10 years of surveillance data to describe lis- teriosis frequency in Germany. Altogether, 5,576 cases were reported, 91% not pregnancy associated; case counts increased over time. Case-fatality rate was 13% in ...
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2021-12-09ZeitschriftenartikelUnivariable associations between a history of incarceration and HIV and HCV prevalence among people who inject drugs across 17 countries in Europe 2006 to 2020 – is the precautionary principle applicable? Background People who inject drugs (PWID) are frequently incarcerated, which is associated with multiple negative health outcomes. Aim We aimed to estimate the associations between a history of incarceration and ...
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2021-04-14ZeitschriftenartikelA Real-Time Thermal Sensor System for Quantifying the Inhibitory Effect of Antimicrobial Peptides on Bacterial Adhesion and Biofilm Formation The increasing rate of antimicrobial resistance (AMR) in pathogenic bacteria is a global threat to human and veterinary medicine. Beyond antibiotics, antimicrobial peptides (AMPs) might be an alternative to inhibit the ...
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2021-06-08Zeitschriftenartikel“How Come You Don’t Call Me?” Smartphone Communication App Usage as an Indicator of Loneliness and Social Well-Being across the Adult Lifespan during the COVID-19 Pandemic Loneliness and lack of social well-being are associated with adverse health outcomes and have increased during the COVID-19 pandemic. Smartphone communication data have been suggested to help monitor loneliness, but this ...
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2021-02-03ZeitschriftenartikelYears of Life Lost to Death Background: Knowing which diseases and causes of death account for most of the years of life lost (YLL) can help to better target appropriate prevention and intervention measures. The YLL in Germany for specific causes of ...
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2021-04-24ZeitschriftenartikelGeneralized cowpox virus infection in an immunosuppressed patient
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2021-04-27ZeitschriftenartikelCorrigendum: Genome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in Staphylococcus aureus
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2021-09-09ZeitschriftenartikelWhat WGS Reveals about Salmonella enterica subsp. enterica in Wildlife in Germany The aim of this study was to gain an overview of the genetic diversity of Salmonella found in wildlife in Germany. We were particularly interested in exploring whether wildlife acts as a reservoir of certain serovars/subtypes ...
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2021-02-10ZeitschriftenartikelToward an Integrated Genome-Based Surveillance of Salmonella enterica in Germany Despite extensive monitoring programs and preventative measures, Salmonella spp. continue to cause tens of thousands human infections per year, as well as many regional and international food-borne outbreaks, that are of ...
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2021-01-17ZeitschriftenartikelEstimating the impact of tax policy interventions on the projected number and prevalence of adults with type 2 diabetes in Germany between 2020 and 2040 Introduction As a population-wide intervention, it has been proposed to raise taxes on unhealthy products to prevent diseases such as type 2 diabetes. In this study, we aimed to estimate the effect of tax policy interventions ...
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2021-12-09ZeitschriftenartikelFirst Comparative Analysis of Clostridium septicum Genomes Provides Insights Into the Taxonomy, Species Genetic Diversity, and Virulence Related to Gas Gangrene Clostridium septicum is a Gram-positive, toxin-producing, and spore-forming bacterium that is recognized, together with C. perfringens, as the most important etiologic agent of progressive gas gangrene. Clostridium septicum ...
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2021-09-29ZeitschriftenartikelGenome Sequence Analysis of Clostridium chauvoei Strains of European Origin and Evaluation of Typing Options for Outbreak Investigations Black quarter caused by Clostridium (C.) chauvoei is an important bacterial disease that affects cattle and sheep with high mortality. A comparative genomics analysis of 64 C. chauvoei strains, most of European origin and ...