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Anzeige der Publikationen 10961-10980 von 12261
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2011-12-12ZeitschriftenartikelMeasles outbreak in an asylum-seekers' shelter in Germany: comparison of the implemented with a hypothetical containment strategy In order to contain a measles outbreak in a German asylum-seekers' shelter, serological testing of all residents was performed, followed by selective vaccination of those with negative test results/not tested. In this paper ...
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2009-03-17ZeitschriftenartikelSurvey and case-control study during epidemics of Puumala virus infection In Baden-Wuerttemberg, a federal state in south-west Germany, a large outbreak of 1089 laboratory-confirmed human Puumala virus (PUUV) infections occurred in 2007. We conducted a survey to describe the disease burden and ...
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2012-11-26ZeitschriftenartikelFrequent Combination of Antimicrobial Multiresistance and Extraintestinal Pathogenicity in Escherichia coli Isolates from Urban Rats (Rattus norvegicus) in Berlin, Germany Urban rats present a global public health concern as they are considered a reservoir and vector of zoonotic pathogens, including Escherichia coli. In view of the increasing emergence of antimicrobial resistant E. coli ...
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2010-12-09ZeitschriftenartikelFlagellin genes of Yersinia enterocolitica biotype 1A: playground of evolution towards novel flagellin functions Yersinia enterocolitica strain 8081, representing the high-pathogenic biotype 1B, harbours three flagellin genes arranged in tandem in the order fliC3, fliC, fliC2. The genes are organized monocistronic but coordinately ...
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2011-12-05ZeitschriftenartikelCharacterization of a monoclonal anti-capsid antibody that cross-reacts with three major primate lentivirus lineages Mouse monoclonal antibodies with varying specificities against the Gag capsid of simian and human immunodeficiency virus (SIV/HIV) were generated by immunizing mice with whole inactivated SIVagmTYO-1. Monoclonal antibody ...
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2012-09-11ZeitschriftenartikelIllegitimate recombination: An efficient method for random mutagenesis in Mycobacterium avium subsp. hominissuis Background: The genus Mycobacterium (M.) comprises highly pathogenic bacteria such as M. tuberculosis as well as environmental opportunistic bacteria called non-tuberculous mycobacteria (NTM). While the incidence of ...
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2012-11-23ZeitschriftenartikelPrevalence, determinants and spectrum of attention-deficit hyperactivity disorder (ADHD) medication of children and adolescents in Germany: results of the German Health Interview and Examination Survey (KiGGS) Objective: To investigate the prevalence, determinants and spectrum of attention-deficit hyperactivity disorder (ADHD) medication and its associations with socioeconomic status (SES), health-related behaviour and living ...
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2012-11-07ZeitschriftenartikelHIV-Prevalence in Tuberculosis Patients in Germany, 2002–2009: An Estimation Based on HIV and Tuberculosis Surveillance Data Tuberculosis (TB) and HIV comorbidity is a major challenge in TB prevention and control but difficult to assess in Germany as in other countries, where data confidentiality precludes notifying the HIV status of TB patients. ...
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2012-11-06ZeitschriftenartikelImpaired pten expression in human malignant peripheral nerve sheath tumours. Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type 1 (NF1). Molecular alterations contributing to MPNST formation ...
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2012-10-05ZeitschriftenartikelPersonal attributes that influence the adequate management of hypertension and dyslipidemia in patients with type 2 diabetes. Results from the DIAB-CORE Cooperation Background: Hypertension and dyslipidemia are often insufficiently controlled in persons with type 2 diabetes (T2D) in Germany. In the current study we evaluated individual characteristics that are assumed to influence ...
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2011-11-15ZeitschriftenartikelFatal dengue hemorrhagic fever imported into Germany Dengue virus (DENV) is an arthropod-borne virus (family Flaviviridae) causing dengue fever or dengue hemorrhagic fever. Here, we report the first fatal DENV infection imported into Germany. A female traveler was hospitalized ...
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2011-11-18ZeitschriftenartikelSynergistic Adaptive Mutations in the Hemagglutinin and Polymerase Acidic Protein Lead to Increased Virulence of Pandemic 2009 H1N1 Influenza A Virus in Mice Influenza impressively reflects the paradigm of a viral disease in which continued evolution of the virus is of paramount importance for annual epidemics and occasional pandemics in humans. Because of the continuous threat ...
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2012-08-28ZeitschriftenartikelAn overview of the European Health Examination Survey Pilot Joint Action Background: Health Examination Surveys (HESs) can provide essential information on the health and health determinants of a population, which is not available from other data sources. Nevertheless, only some European ...
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2011-01-16ZeitschriftenartikelPrimary snoring in school children: prevalence and neurocognitive impairments. Purpose: We aimed to investigate the prevalence of primary snoring (PS) and its association with neurocognitive impairments. Methods: Data from a community-based study in 1,114 primary school children were used to ...
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2012-04-01ZeitschriftenartikelInfection Barriers to Successful Xenotransplantation Focusing on Porcine Endogenous Retroviruses Xenotransplantation may be a solution to overcome the shortage of organs for the treatment of patients with organ failure, but it may be associated with the transmission of porcine microorganisms and the development of ...
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2011-10-29ZeitschriftenartikelVaccination against pandemic H1N1 (2009) in patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis Purpose: Limited data are available on immunologic responses to primary pandemic H1N1 (2009) vaccination in recipients of allogeneic hematopoietic stem cell transplantation (HSCT) recipients. In 2009 serologic responses ...
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2011-01-01ZeitschriftenartikelVaccines for Leishmaniasis: From proteome to vaccine candidates Leishmania spp. cause a wide spectrum of tropical diseases which are threatening an estimated 350 million people around the globe. While in most cases non-fatal, the disease is associated with high morbidity, social stigmata ...
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2012-04-19ZeitschriftenartikelThe risk of AIDS-defining events is decreasing over time in the German HIV-1 Seroconverter Cohort Background: With ageing of the HIV-infected population, long-term exposure to treatment, varying adherence, emerging resistance and complications to therapies, effectiveness of Highly Active Antiretroviral Therapy (HAART) ...
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2012-11-06ZeitschriftenartikelHeterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) Gene and Metabolic Risk Factors in the EPIC-Potsdam Study Background: Stearoyl-CoA desaturase-1 (SCD1) is an enzyme involved in lipid metabolism. In mice and humans its activity has been associated with traits of the metabolic syndrome, but also with the prevention of saturated ...
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2012-11-09ZeitschriftenartikelSerum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols Robust and sensitive ELISPOT protocols are commonly applied concomitant with the development of new immunotherapeutics. Despite the knowledge that individual serum batches differ in their composition and may change properties ...