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2017-03-09ZeitschriftenartikelChanges in prevalence of psychotropic drug use and alcohol consumption among the elderly in Germany: results of two National Health Interview and Examination Surveys 1997-99 and 2008-11 Background: Psychotropic drug use and alcohol consumption among older adults need to be monitored over time as their use or combined use bears risks of harms. Representative data on changes in prevalence, patterns and ...
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2017-05-31ZeitschriftenartikelDecreased emergence of HIV-1 drug resistance mutations in a cohort of Ugandan women initiating option B+ for PMTCT Background: Since 2012, WHO guidelines for the prevention of mother-to-child transmission (PMTCT) of HIV-1 in resource-limited settings recommend the initiation of lifelong antiretroviral combination therapy (cART) for ...
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2017-05-25ZeitschriftenartikelMicrobial functionality as affected by experimental warming of a temperate mountain forest soil—A metaproteomics survey Soil microbes play an important role in terrestrial carbon (C) cycling, but their functional response to global warming remains yet unclear. Soil metaproteomics has the potential to contribute to a better understanding of ...
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2017-05-18ZeitschriftenartikelWhy are some people more fit than others? Correlates and determinants of cardiorespiratory fitness in adults: protocol for a systematic review Background: Cardiorespiratory fitness (CRF) is a physical condition that is now well established as a predictor of numerous adverse health outcomes, independent of physical activity levels. In order to be able to improve ...
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2017-02-12ZeitschriftenartikelImpact of Outpatient Neuraminidase Inhibitor Treatment in Patients Infected With Influenza A(H1N1)pdm09 at High Risk of Hospitalization: An Individual Participant Data Metaanalysis Background: While evidence exists to support the effectiveness of neuraminidase inhibitors (NAIs) in reducing mortality when given to hospitalized patients with A(H1N1)pdm09 virus infection, the impact of outpatient ...
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2017-05-22ZeitschriftenartikelParvovirus B19-induced vascular damage in the heart is associated with elevated circulating endothelial microparticles Background: Diagnosis of viral myocarditis is difficult by clinical criteria but facilitated by detection of inflammation and viral genomes in endomyocardial biopsies. Parvovirus B19 (B19V) targets endothelial cells ...
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2017-05-18ZeitschriftenartikelTemporal dynamics of online petitions Online petitions are an important avenue for direct political action, yet the dynamics that determine when a petition will be successful are not well understood. Here we analyze the temporal characteristics of online-petition ...
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2017-05-01ZeitschriftenartikelEbola management centre proximity associated with reduced delays of healthcare of Ebola Virus Disease (EVD) patients, Tonkolili, Sierra Leone, 2014–15 Between August-December 2014, Ebola Virus Disease (EVD) patients from Tonkolili District were referred for care to two Médecins Sans Frontières (MSF) Ebola Management Centres (EMCs) outside the district (distant EMCs). In ...
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2017-06-02ZeitschriftenartikelCharacteristics of participants in a randomized trial of an Internet intervention for depression (EVIDENT) in comparison to a national sample (DEGS1) Background: While the efficacy of Internet interventions for depression has been demonstrated in numerous studies, there is concern that the participants in these studies may systematically differ from depressed subjects ...
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2017-06-10ZeitschriftenartikelPhysical health-related quality of life in relation to metabolic health and obesity among men and women in Germany Background: This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower ...
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2017-06-06ZeitschriftenartikelChanging educational inequalities in sporting inactivity among adults in Germany: a trend study from 2003 to 2012 Background: Social inequalities in health can be explained in part by the social patterning of leisure-time physical activity, such as non-participation in sports. This study is the first to explore whether absolute and ...
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2017-06-08ZeitschriftenartikelGenome Sequence of Paracoccus contaminans LMG 29738T, Isolated from a Water Microcosm We announce here the complete genome sequence of Paracoccus contaminans LMG 29738T, which we recently isolated from a contaminated water microcosm. The genome consists of a 2.94-Mb chromosome and a 94-kb plasmid. To our ...
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2017-05-18ZeitschriftenartikelIdentification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland Hepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). ...
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2017-06-22ZeitschriftenartikelFallbericht: Ein möglicher Fallstrick in der akuten Differenzialdiagnose einer bakteriellen Meningitis Aktuelle Kommentare in Leitlinien zeigen, dass es bei akuten bakteriellen Meningitis-Erkrankungen nicht in jedem Fall gelingt aus einer Liquorprobe einen mikroskopischen oder kulturellen Erregernachweis zu erzielen.1,2 ...
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2017-05-25ZeitschriftenartikelOngoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxinproducing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017 We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting ...
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2017-05-19ZeitschriftenartikelVaricella-zoster virus seroprevalence in children and adolescents in the pre-varicella vaccine era, Germany Background: In 2004, universal childhood varicella vaccination was introduced in Germany. We aimed to determine the age-specific prevalence of anti-varicella zoster virus (VZV) IgG-antibodies among children in the ...
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2017-05-24ZeitschriftenartikelWorkshop Bericht: Drei Jahre bundesweite Keuchhusten-Meldepflicht Erfahrungsaustausch zwischen ÖGD, Ärzteschaft und beteiligten Laboren zur Identifizierung von Maßnahmen zur Verbesserung der SurveillanceSeit März 2013 gibt es eine bundesweite Meldepflicht für Keuchhusten, zuvor war Keuchhusten in den fünf östlichen Bundesländern seit längerem meldepflichtig gewesen. Im Epidemiologischen Bulletin 21/2017 ist ...
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2017-06-01ZeitschriftenartikelBeantwortung der Frage: Infektion mit Wildvirus oder Impfvirus als Ursache eines Masernexanthems Neu entwickelte Diagnostik am NRZ für Masern, Mumps und RötelnBesteht ein Masern-Verdacht, muss der Patient isoliert werden, bis das Ergebnis der Laboruntersuchung vorliegt. Darüber hinaus müssen ungeschützte Kontaktpersonen möglichst schnell gefunden und über die Möglichkeit ...
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2017-06-15ZeitschriftenartikelPrävention von MRE innerhalb regionaler Netzwerke: Zertifizierung von stationären und ambulanten Einrichtungen Eine der größten Herausforderungen unseres Gesundheitssystems ist, der Entstehung und Weiterverbreitung multiresistenter Erreger (MRE) entgegenzuwirken. Vom Gesetzgeber wurde die Koordinierung dieser Aufgabe u. a. ...
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2017-05-30ZeitschriftenartikelStructural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica The giant non-fimbrial adhesin SiiE of Salmonella enterica mediates the first contact to the apical site of epithelial cells and enables subsequent invasion. SiiE is a 595 kDa protein composed of 53 repetitive bacterial ...