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2017-04-04ZeitschriftenartikelEvaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial Background: Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population ...
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2017-04-11ZeitschriftenartikelIs the impact of childhood influenza vaccination less than expected: a transmission modelling study Background: To reduce the burden of severe influenza, most industrialized countries target specific risk-groups with influenza vaccines, e.g. the elderly or individuals with comorbidities. Since children are the main ...
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2017-04-13ZeitschriftenartikelDie Echinokokkose – Eine Übersicht und neue Erkenntnisse in der Diagnostik, Therapie und Parasitenbiologie Zu den vielen mit dem Attribut „selten aber gefährlich“ versehenen Krankheiten in Deutschland gehören zweifelsfrei die Alveoläre und die Zystische Echinokokkose, die durch die Metazestoden-Larvenstadien des Fuchs- bzw. ...
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2017-03-28ZeitschriftenartikelSLIMM: species level identification of microorganisms from metagenomes Identification and quantification of microorganisms is a significant step in studying the alpha and beta diversities within and between microbial communities respectively. Both identification and quantification of a given ...
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2017-03-27ZeitschriftenartikelChanges to cholesterol trafficking in macrophages by Leishmania parasites infection Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases. It has been demonstrated that host cholesterol ...
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2017-03-21ZeitschriftenartikelNursing staff fluctuation and pathogenic burden in the NICU - effective outbreak management and the underestimated relevance of non-resistant strains In the course of a hospital management takeover, a microbial outbreak took place in a tertiary neonatal intensive care unit (NICU). Here, we characterize the outbreak and its management. About 4 months prior to takeover, ...
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2017-03-29ZeitschriftenartikelPredicting late-onset sepsis by routine neonatal screening for colonisation by gram-negative bacteria in neonates at intensive care units: a protocol for a systematic review Introduction: Hospitals conduct extensive screening procedures to assess colonisation of the body surface of neonates by gram-negative bacteria to avoid complications like late-onset sepsis. However, the benefits of these ...
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2017-03-14ZeitschriftenartikelWild African great apes as natural hosts of malaria parasites: current knowledge and research perspectives Humans and African great apes (AGAs) are naturally infected with several species of closely related malaria parasites. The need to understand the origins of human malaria as well as the risk of zoonotic transmissions and ...
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2016-08-28ZeitschriftenartikelPhylogenetic structure of European Salmonella Enteritidis outbreak correlates with national and international egg distribution network Outbreaks of Salmonella Enteritidis have long been associated with contaminated poultry and eggs. In the summer of 2014 a large multi-national outbreak of Salmonella Enteritidis phage type 14b occurred with over 350 cases ...
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2017-04-06ZeitschriftenartikelDepression in der Bevölkerung: Diagnoseraten im Versorgungskontext und epidemiologische Befunde Während Kostenträger in Deutschland von einem erheblichen Anstieg an Arbeitsunfähigkeit und Frühberentung aufgrund depressiver Störungen seit über 15 Jahren berichten, wird in den epidemiologischen Daten jedoch kein ...
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2017-03-20ZeitschriftenartikelCo-circulation of West Nile virus and distinct insect-specific flaviviruses in Turkey Background: Active vector surveillance provides an efficient tool for monitoring the presence or spread of emerging or re-emerging vector-borne viruses. This study was undertaken to investigate the circulation of ...
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2017-03-30ZeitschriftenartikelKontaktpersonen-Nachverfolgung nach einem Todesfall eines XDR-Tuberkulosepatienten in einem Flugzeug, Deutschland 2013 Im Juli 2013 wurde an die zuständigen deutschen Gesundheitsbehörden ein ungewöhnliches Ereignis gemeldet: Ein junger erwachsener Passagier mit XDR-Tuberkulose, der von der Türkei nach Deutschland flog, verstarb kurz nach ...
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2017-03-10ZeitschriftenartikelTreatment outcome in children with nontuberculous mycobacterial lymphadenitis: A retrospective follow-up study Introduction: Information on the long-term treatment outcome following nontuberculous mycobacterial (NTM) lymphadenitis is very limited. We performed a study to (a) compare cure rates following different initial treatment ...
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2017-03-23ZeitschriftenartikelContact investigation after a fatal case of extensively drug-resistant tuberculosis (XDR-TB) in an aircraft, Germany, July 2013 In July 2013, a passenger died of infectious extensively drug-resistant tuberculosis (XDR-TB) on board of an aircraft after a 3-hour flight from Turkey to Germany. Initial information indicated the patient had moved about ...
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2017-03-20ZeitschriftenartikelGerman Health Update: New data for Germany and Europe The background to and methodology applied in GEDA 2014/2015-EHIS GEDA 2014/2015-EHIS is an up-to-date health survey of the adult population undertaken within the framework of the Robert Koch Institute’s (RKI) health monitoring system. It uses the EHIS (European Health Interview Survey) ...
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2017-03-20ZeitschriftenartikelDiabetes Surveillance in Germany – Background, concept and prospects Diabetes mellitus is a chronic disease that is associated with serious health problems and high costs. According to estimates gained from nationally representative health surveys conducted by the Robert Koch Institute ...
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2017-03-20ZeitschriftenartikelHealth and healthcare provision to asylum seekers and refugees in Germany The wars and devastation of recent years have driven many people to flee their homes. Great numbers of asylum seekers and refugees have sought protection in Europe. In 2015 and 2016 alone, over one million people applied ...
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2017-03-20Zeitschriftenartikel12-Month prevalence of stroke or chronic consequences of stroke in Germany Stroke is the second most common cause of death globally and an important cause of disability in adults. According to the GEDA 2014/2015-EHIS study, 1.6% of adults (1.7% of women and 1.5% of men) in Germany had a stroke ...
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2017-03-20Zeitschriftenartikel12-Month prevalence of coronary heart disease in Germany The results of the GEDA 2014/2015-EHIS study demonstrate that during the last 12 months, 3.7% of women and 6.0% of men in Germany had coronary heart disease (CHD – defined as myocardial infarction, chronic consequences ...
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2017-03-20Zeitschriftenartikel12-Month prevalence of hypertension in Germany Hypertension is among the most important risk factors for cardiovascular diseases and therefore a significant determinant of the most frequent causes of death in adults. According to the GEDA 2014/2015-EHIS survey nearly ...