edoc.rki.de - Open Access Publikationsserver: Recent submissions
Now showing items 41-60 of 13018
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2024-10-13ZeitschriftenartikelReconsidering inequalities in COVID-19 vaccine uptake in Germany: a spatiotemporal analysis combining individual educational level and area-level socioeconomic deprivation Combining the frameworks of fundamental causes theory and diffusion of innovation, scholars had anticipated a delayed COVID-19 vaccination uptake for people in lower socioeconomic position depending on the socioeconomic ...
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2024-01-31ZeitschriftenartikelSelective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology of the related Marburg virus is much ...
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2024-04-06ZeitschriftenartikelCorrigendum to “Past and present seroprevalence and disease burden estimates of Toxoplasma gondii infections in Germany: An appreciation of the role of serodiagnostics” [Int. J. Med. Microbiol. 313 (2023) 151592]
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2024-02-08ZeitschriftenartikelPresence of hypervirulence-associated determinants in Klebsiella pneumoniae from hospitalised patients in Germany Background: Klebsiella (K.) pneumoniae is a ubiquitous Gram-negative bacterium and a common coloniser of animals and humans. Today, K. pneumoniae is one of the most persistent nosocomial pathogens worldwide and poses a ...
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2024-10-21ZeitschriftenartikelHigh-resolution modeling and projection of heat-related mortality in Germany under climate change Background: Heat has become a leading cause of preventable deaths during summer. Understanding the link between high temperatures and excess mortality is crucial for designing effective prevention and adaptation plans. ...
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2024-05-24ZeitschriftenartikelInterpretable molecular encodings and representations for machine learning tasks Molecular encodings and their usage in machine learning models have demonstrated significant breakthroughs in biomedical applications, particularly in the classification of peptides and proteins. To this end, we propose a ...
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2024-02-09ZeitschriftenartikelBarriers and drivers to COVID-19 vaccination among the migrant and non-migrant population in Germany, 2021 Background: During the Coronavirus Disease 2019 (COVID-19) pandemic, immunization programmes struggled to reach all population groups equally. While migrant groups face multiple barriers to health systems, including ...
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2024-05-02ZeitschriftenartikelHuman macrophages infected with Egyptian Rousette bat-isolated Marburg virus display inter-individual susceptibility and antiviral responsiveness Marburg virus (MARV) is a highly pathogenic filovirus and a causative agent of sporadic zoonotic viral hemorrhagic fever outbreaks with high case fatality rates. In humans, filoviruses like MARV and Zaire Ebola virus (EBOV) ...
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2024-12-21ZeitschriftenartikelThe impact of information and communication technology on immunisation and immunisation programmes in low-income and middle-income countries: a systematic review and meta-analysis Background: Low-income and Middle-income Countries (LMIC) are continually working to ensure everyone can access life-saving vaccines. Recognising the considerable impact of Information and Communication Technology (ICT) ...
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2024-01-20ZeitschriftenartikelVaccine-induced neutralizing antibodies bind to the H protein of a historical measles virus Measles is a highly contagious airborne viral disease. It can lead to serious complications and death and is preventable by vaccination. The live-attenuated measles vaccine (LAMV) derived from a measles virus (MV) isolated ...
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2024-03-27ZeitschriftenartikelGene knock-out in Mycobacterium abscessus using Streptococcus thermophilus CRISPR/Cas The CRISPRi system using dCas9Sth1 from Streptococcus thermophilus developed for Mycobacterium tuberculosis and M. smegmatis was modified to allow gene knock-out in M. abscessus. Efficacy of the knock-out system was evaluated ...
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2024-08-14ZeitschriftenartikelSozial gerecht: Gesundheit – Umwelt – Klima Tagungsbericht zum Kongress Armut und Gesundheit 2024
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2024-01-20ZeitschriftenartikelGenome sequencing of the mpox virus 2022 outbreak with amplicon-based Oxford Nanopore MinION sequencing We present an amplicon-based assay for MinION Nanopore sequencing of mpox virus (MPXV) genomes from clinical specimens, obtaining high-quality results with an average genome coverage of 99% for Ct values of up to 25, and ...
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2024-02-26ZeitschriftenartikelListening to the Voices of Health Care Workers During the COVID-19 Pandemic: A Qualitative Study Providing In-Depth Insights Into Ethical and Individual Challenges In their daily practice, health care workers (HCWs) experience the effects of tensions between professional ethos and work realities, which can lead to ethical dilemmas. We aim to explore the ethical dilemmas that affected ...
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2023-12-22ZeitschriftenartikelStructure–function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophospholipase A PlaA Legionella pneumophila, the causative agent of a life-threatening pneumonia, intracellularly replicates in a specialized compartment in lung macrophages, the Legionella-containing vacuole (LCV). Secreted proteins of the ...
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2024-09-26ZeitschriftenartikelChronic Kidney Disease and Kidney Stone in a Wild Chimpanzee (Pan troglodytes verus) in Côte d'Ivoire An older wild female chimpanzee (Pan troglodytes) was found dead with a large calcium oxalate stone in the renal pelvis. Histopathological changes included glomerulosclerosis, interstitial nephritis and fibrosis, focal ...
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2024-05-28ZeitschriftenartikelOesophagostomum stephanostomum causing parasitic granulomas in wild chimpanzees (Pan troglodytes verus) of Taï National Park, Côte d'Ivoire Nematodes belonging to the genus Oesophagostomum frequently infect wild chimpanzees (Pan troglodytes) across widely separated field sites. Nodular lesions (granulomas) containing Oesophagostomum are commonly seen in the ...
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2024-10-09ZeitschriftenartikelCardiovascular Risk in Childhood is Associated With Carotid Intima-Media Thickness and Stiffness in Adolescents and Young Adults: The KiGGS Cohort Purpose: Cardiovascular risk factors are widespread among children and adolescents and may lead to accelerated vascular aging in middle adulthood. However, data are scarce on shorter-term consequences, for example, on ...
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2024-03-21ZeitschriftenartikelNeeds and feasibility of living systematic reviews (LSRs): Experience from LSRs on COVID-19 vaccine effectiveness During 2021 and 2023, a team of researchers at the Robert Koch Institute (RKI) and partnering institutions conducted two living systematic reviews (LSRs) on the effectiveness of COVID-19 vaccines in different age groups ...
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2024-11-19ZeitschriftenartikelDiagnostic electron microscopy in human infectious diseases – Methods and applications Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted ...