edoc.rki.de - Open Access Publikationsserver: Recent submissions
Now showing items 401-420 of 12079
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2021-02-10ZeitschriftenartikelSocioeconomic inequalities in primary-care and specialist physician visits: a systematic review Background Utilization of primary-care and specialist physicians seems to be associated differently with socioeconomic status (SES). This review aims to summarize and compare the evidence on socioeconomic inequalities ...
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2021-03-16ZeitschriftenartikelScreening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis Purpose Studies on the occurrence of ocular toxoplasmosis (OT) in a general population are rare. Therefore, we conducted this pilot study to assess whether a nonmydriatic ultra-wide-field (UWF) scanning laser ophthalmoscope ...
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2021-12-11ZeitschriftenartikelMonitoring for COVID-19 by universal testing in a homeless shelter in Germany: a prospective feasibility cohort study Background Living conditions in homeless shelters facilitate the transmission of COVID-19. Social determinants and pre-existing health conditions place homeless people at increased risk of severe disease. Described ...
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2021-12-20ZeitschriftenartikelPreclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2 New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical ...
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2021-04-16ZeitschriftenartikelStability of BSE infectivity towards heat treatment even after proteolytic removal of prion protein The unconventional infectious agents of transmissible spongiform encephalopathies (TSEs) are prions. Their infectivity co-appears with PrPSc, aberrant depositions of the host’s cellular prion protein (PrPC). Successive ...
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2021-12-21ZeitschriftenartikelComparative in vitro activity of piperacillin-tazobactam and temocillin against third-generation cephalosporin-resistant, carbapenem-susceptible Escherichia coli and Klebsiella pneumoniae Carbapenems are considered the drugs of choice for first-line treatment of severe infections caused by carbapenem-susceptible, extended-spectrum β-lactamases (ESBL)-producing Enterobacterales, while piperacillin-tazobactam ...
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2021-05-12ZeitschriftenartikelAltersspezifische Trends des risikoreichen Alkoholkonsums in Deutschland: Parallele oder unterschiedliche Verläufe? Einleitung Nach der Collectivity-of-Drinking-Cultures-Theorie von Skog finden Veränderungen des Alkoholkonsums in allen Bevölkerungsgruppen und -schichten als parallele Verschiebungen statt. Ziele des vorliegenden ...
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2021-07-29ZeitschriftenartikelCOVID-19-Patientinnen und -Patienten in Deutschland: Expositionsrisiken und assoziierte Faktoren für Hospitalisierungen und schwere Krankheitsverläufe Das Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2) hat sich seit 2020 weltweit verbreitet. In Deutschland haben sich bis zum Ende Juni 2021 über 3,7 Mio. Menschen infiziert. Das Infektionsgeschehen ...
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2021-07-26ZeitschriftenartikelStudies in Ecological Rationality Ecological rationality represents an alternative to classic frameworks of rationality. Extending on Herbert Simon's concept of bounded rationality, it holds that cognitive processes, including simple heuristics, are not ...
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2021-10-26ZeitschriftenartikelReciprocal circulation pattern of SARS-CoV-2 and influenza viruses during the influenza seasons 2019/2020 and 2020/2021 in the Bavarian Influenza Sentinel (Germany) The corona virus disease-2019 (COVID-19) pandemic began in Wuhan, China, and quickly spread around the world. The pandemic overlapped with two consecutive influenza seasons (2019/2020 and 2020/2021). This provided the ...
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2021-06-21ZeitschriftenartikelRhinovirus prevalence as indicator for efficacy of measures against SARS-CoV-2 Background: Non-pharmaceutical measures to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) should be carefully tuned as they can impose a heavy social and economic burden. To quantify and ...
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2021-12-11ZeitschriftenartikelEvaluation of community readiness for change prior to a participatory physical activity intervention in Germany A lack of communities’ readiness for change is reported as a major barrier toward an effective imple- mentation of health promoting interventions in community settings. Adding an alternative readiness assessment approach ...
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2021-07-23ZeitschriftenartikelHot days and Covid-19: Online survey of nurses and nursing assistants to assess occupational heat stress in Germany during summer 2020 Objectives: Our aim was to identify if working during hot days while wearing Covid-19 related personal pro- tective equipment causes occupational heat stress for nurses and nursing assistants in Germany. Design: Using ...
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2021-05-11ZeitschriftenartikelThe large extracellular loop of CD63 interacts with gp41 of HIV-1 and is essential for establishing the virological synapse Human immunodeficiency virus type 1 (HIV-1) persists lifelong in infected individuals and has evolved unique strategies in order to evade the immune system. One of these strategies is the direct cell-to-cell spread of ...
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2020-10-08ZeitschriftenartikelA decade of de novo transcriptome assembly: Are we there yet? A decade ago, de novo transcriptome assembly evolved as a versatile and power- ful approach to make evolutionary assumptions, analyse gene expression, and anno- tate novel transcripts, in particular, for non-model organisms ...
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2021-10-13ZeitschriftenartikelLeprosy in wild chimpanzees Humans are considered as the main host for Mycobacterium leprae1, the aetiological agent of leprosy, but spillover has occurred to other mammals that are now maintenance hosts, such as nine-banded armadillos and red ...
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2021-11-25ZeitschriftenartikelAnalysis of BNT162b2- and CVnCoV-elicited sera and of convalescent sera toward SARS-CoV-2 viruses Background The mRNA vaccine BNT162b2 (Comirnaty, BioNTech/Pfizer) and the vaccine candidate CVnCoV (Curevac) each encode a stabilized spike protein of SARS-CoV2 as antigen but differ with respect to the nature of the ...
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2021-07-07ZeitschriftenartikelRecommendations to plan a national burden of disease study Background: The InfAct (Information for Action) project is a European Commission Joint Action on Health Information which has promoted the potential role of burden of disease (BoD) approaches to improve the current European ...
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2020-10-06ZeitschriftenartikelRisk of human-to-wildlife transmission of SARS-CoV-2 It has been a long time since the world has experienced a pandemic with such a rapid devastating impact as the current COVID-19 pandemic. The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ...
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2021-06-27ZeitschriftenartikelState of Medical Mycology at German Academic Medical Centres: A Survey of the German-Speaking Mycological Society (DMYKG) and the Paul-Ehrlich-Society for Chemotherapy (PEG) Background Little is known about the infrastructure to translate advances in the management of patients at risk to develop invasive opportunistic fungal diseases. To assess the current state of Medical Mycology support ...