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Anzeige der Publikationen 10801-10820 von 12594
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2013-10-23ZeitschriftenartikelCytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+CD4- dendritic cells Cytomegaloviruses (CMV) have developed various strategies to escape the immune system of the host. One strategy involves the expression of virus-encoded chemokines to modulate the host chemokine network. We have identified ...
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2014-05-01ZeitschriftenartikelFirst Line Treatment Response in Patients with Transmitted HIV Drug Resistance and Well Defined Time Point of HIV Infection: Updated Results from the German HIV-1 Seroconverter Study Background: Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided ...
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2014-04-21ZeitschriftenartikelTwo Novel EHEC/EAEC Hybrid Strains Isolated from Human Infections The so far highest number of life-threatening hemolytic uremic syndrome was associated with a food-borne outbreak in 2011 in Germany which was caused by an enterohemorrhagic Escherichia coli (EHEC) of the rare serotype ...
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2014-04-10ZeitschriftenartikelPatterns of Transmitted HIV Drug Resistance in Europe Vary by Risk Group Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to ...
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2014-04-14ZeitschriftenartikelContinued vigilance – development of an online evaluation tool for assessing preparedness of medical facilities for biological events Objective: Effective response to biological events necessitates ongoing evaluation of preparedness. This study was a bilateral German–Israeli collaboration aimed at developing an evaluation tool for assessing preparedness ...
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2014-04-24ZeitschriftenartikelSeasonal influenza immunisation in Europe. Overview of recommendations and vaccination coverage for three seasons: pre-pandemic (2008/09), pandemic (2009/10) and post-pandemic (2010/11) Since 2008, annual surveys of influenza vaccination policies, practices and coverage have been undertaken in 29 European Union (EU)/ European Economic Area (EEA) countries. After 2009, this monitored the impact of European ...
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2014-04-11ZeitschriftenartikelPrevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus Background: Increased risk of osteoporosis and its clinical significance in patients with diabetes is controversial. We analyze osteoporosis prevalence and determinants of bone mineral density (BMD) in patients with ...
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2014-04-10ZeitschriftenartikelResults of surveillance for infections with Shiga toxinproducing Escherichia coli (STEC) of serotype O104:H4 after the large outbreak in Germany, July to December 2011 After the massive outbreak of infections with Shiga toxin-producing Escherichia coli (STEC) of serotype O104:H4 in Germany in the summer of 2011, post-outbreak surveillance for further infections with this type of STEC was ...
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2014-03-01ZeitschriftenartikelNeue Broschüre »Krebs in Deutschland« im Dezember 2013 erschienen Das Zentrum für Krebsregisterdaten (ZfKD) im Robert Koch-Institut (RKI) hat im Dezember 2013 gemeinsam mit der Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V. (GEKID) die neue Broschüre »Krebs in ...
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2013-03-26ZeitschriftenartikelStaphylococcus aureus toxins – Their functions and genetics The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges from life-threatening infection through allergic reactions to symptom-free colonization. The pan-genome of this bacterial species encodes ...
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2013-04-05ZeitschriftenartikelChronische somatische Erkrankungen und Beeinträchtigung der psychischen Gesundheit bei Erwachsenen in Deutschland Ergebnisse der bevölkerungsrepräsentativen Querschnittstudie Gesundheit in Deutschland aktuell (GEDA) 2010
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2013-12-12ZeitschriftenartikelReverse Transcription Recombinase Polymerase Amplification Assay for the Detection of Middle East Respiratory Syndrome Coronavirus The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the eastern Mediterranean and imported cases to Europe has alerted public health authorities. Currently, detection of MERS-CoV in patient samples ...
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2014-02-20ZeitschriftenartikelUnifying Viral Genetics and Human Transportation Data to Predict the Global Transmission Dynamics of Human Influenza H3N2 Information on global human movement patterns is central to spatial epidemiological models used to predict the behavior of influenza and other infectious diseases. Yet it remains difficult to test which modes of dispersal ...
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2014-03-22ZeitschriftenartikelSurveillance des Antibiotikaverbrauchs in Krankenhäusern Durch das „Gesetz zur Änderung des Infektionsschutzgesetzes und anderer Gesetze“ vom 28. Juli 2011 (BGBL. I S. 1622) wurde die Verpflichtung von Leitern von Krankenhäusern und von Einrichtungen für ambulantes Operieren zur ...
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2014-03-13ZeitschriftenartikelMortality and molecular epidemiology associated with extended-spectrum β-lactamase production in Escherichia coli from bloodstream infection Background: The rate of infections due to extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is growing worldwide. These infections are suspected to be related to increased mortality. We aimed to estimate the ...
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2014-03-21ZeitschriftenartikelQuantitative Influenza Follow-Up Testing (QIFT)—A Novel Biomarker for the Monitoring of Disease Activity at the Point-of-Care Background: Influenza infections induce considerable disease burden in young children. Biomarkers for the monitoring of disease activity at the point-of-care (POC) are currently lacking. Recent methodologies for ...
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2014-03-27ZeitschriftenartikelApplying a correction procedure to the prevalence estimates of overweight and obesity in the German part of the HBSC study Background: Prevalence rates for overweight and obesity based on self-reported height and weight are underestimated, whereas the prevalence rate for underweight is slightly overestimated. Therefore a correction is needed. ...
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2014-04-01ZeitschriftenartikelOrigin Detection During Food-borne Disease Outbreaks – A Case Study of the 2011 EHEC/HUS Outbreak in Germany The key challenge during food-borne disease outbreaks, e.g. the 2011 EHEC/HUS outbreak in Germany, is the design of efficient mitigation strategies based on a timely identification of the outbreak’s spatial origin. Standard ...
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2014-02-27ZeitschriftenartikelArea Level Deprivation Is an Independent Determinant of Prevalent Type 2 Diabetes and Obesity at the National Level in Germany. Results from the National Telephone Health Interview Surveys ‘German Health Update’ GEDA 2009 and 2010 Objective: There is increasing evidence that prevention programmes for type 2 diabetes mellitus (T2DM) and obesity need to consider individual and regional risk factors. Our objective is to assess the independent ...
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2014-03-06ZeitschriftenartikelRapid Molecular Assays for the Detection of Yellow Fever Virus in Low-Resource Settings Background: Yellow fever (YF) is an acute viral hemorrhagic disease transmitted by Aedes mosquitoes. The causative agent, the yellow fever virus (YFV), is found in tropical and subtropical areas of South America and ...