Browsing by Title
Now showing items 1266-1285 of 6654
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2007-10-18ZeitschriftenartikelDifferences in Menopausal Hormone Therapy Use among Women in Germany between 1998 and 2003 Background: To examine the differences in menopausal hormone therapy (MHT) use and user profiles among women in Germany before and after the communication of the Women's Health Initiative (WHI) trial and other study results ...
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2019-12-03ZeitschriftenartikelDifferences in MHC-B diversity and KIR epitopes in two populations of wild chimpanzees The major histocompatibility complex (MHC) class I genes play a critical role within the immune system, both by the presentation of antigens from intracellular pathogens to immunocompetent cells and by the interaction with ...
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2017-05-30ZeitschriftenartikelDifferent features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections Background: Human Ebola infection is characterized by a paralysis of the immune system. A signature of αβ T cells in fatal Ebola infection has been recently proposed, while the involvement of innate immune cells in the ...
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2010-05-01ZeitschriftenartikelDifferential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation. Human endogenous retroviruses (HERVs) are discussed as causative agents of various diseases including cancers. Expression of endogenous retroviral sequences can be induced by ultraviolet (UV) light, which is also considered ...
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2019-03-22ZeitschriftenartikelDifferential Innate Immune Responses Elicited by Nipah Virus and Cedar Virus Correlate with Disparate In Vivo Pathogenesis in Hamsters Syrian hamsters (Mesocricetus auratus) are a pathogenesis model for the Nipah virus (NiV), and we sought to determine if they are also susceptible to the Cedar virus (CedPV). Following intranasal inoculation with CedPV, ...
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2017-06-21ZeitschriftenartikelDifferential Substrate Usage and Metabolic Fluxes in Francisella tularensis Subspecies holarctica and Francisella novicida Francisella tularensis is an intracellular pathogen for many animals causing the infectious disease, tularemia. Whereas F. tularensis subsp. holarctica is highly pathogenic for humans, F. novicida is almost avirulent for ...
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2010-01-27ZeitschriftenartikelDifferentiation of influenza b virus lineages yamagata and victoria by real-time PCR Since the 1970s, influenza B viruses have diverged into two antigenically distinct virus lineages called the Yamagata and Victoria lineages. We present the first real-time PCR assay for virus lineage differentiation to ...
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2010-10-28ZeitschriftenartikelDifferentiation of Medically Important Euro-Asian Tick Species Ixodes ricinus, Ixodes persulcatus, Ixodes hexagonus, and Dermacentor reticulatus by Polymerase Chain Reaction Understanding epidemiology of the tick-borne pathogens requires the accurate identification of the vector ticks. Morphological analysis of ticks is difficult and often leads to misidentification. Molecular techniques offer ...
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2019-03-19ZeitschriftenartikelDigital epidemiology and global health security; an interdisciplinary conversation Contemporary infectious disease surveillance systems aim to employ the speed and scope of big data in an attempt to provide global health security. Both shifts - the perception of health problems through the framework of ...
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2015-12-17ZeitschriftenartikelDilemmas in Managing Pregnant Women With Ebola: 2 Case Reports We report 2 cases of Ebola viral disease (EVD) in pregnant women who survived, initially with intact pregnancies. Respectively 31–32 days after negativation of the maternal blood EVD-polymerase chain reaction (PCR) both ...
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2018-03-08ZeitschriftenartikelDiphtherie Vollständig aktualisierte Fassung vom Januar 2018. Erstveröffentlichung im Epidemiologischen Bulletin 6/2001.Im Epidemiologischen Bulletin 10/2018 ist der vollständig überarbeitete RKI-Ratgeber für Ärzte zu Diphtherie erschienen. Seit 2001 wurden dem Robert Koch-Institut rund 90 Diphtherie-Erkrankungen übermittelt. Das klinische ...
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2013-07-12ZeitschriftenartikelDirect costs of inequalities in health care utilization in Germany 1994 to 2009: a top-down projection Background: Social inequalities in health are a characteristic of almost all European Welfare States. It has been estimated, that this is associated with annual costs that amount to approximately 9% of total member state ...
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2012-10-03ZeitschriftenartikelDirect Detection and Genotyping of KPC Carbapenemases from Urine using a new DNA Microarray Test Klebsiella pneumoniae carbapenemases (KPC) are considered a serious threat to antibiotic therapy as they confer resistance to carbapenems, which are used to treat Extended-spectrum beta-lactamase (ESBL) producing bacteria. ...
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2013-11-05ZeitschriftenartikelDirect RNA-Based Detection and Differentiation of CTX-M-Type Extended-Spectrum β-Lactamases (ESBL) The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with ...
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2010-10-31ZeitschriftenartikelDirect Visualization of Peptide/MHC Complexes at the Surface and in the Intracellular Compartments of Cells Infected In Vivo by Leishmania major Protozoa and bacteria infect various types of phagocytic cells including macrophages, monocytes, dendritic cells and eosinophils. However, it is not clear which of these cells process and present microbial antigens in vivo ...
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2014-04-01ZeitschriftenartikelDisagreement of the two oscillometric blood pressure measurement devices, Datascope Accutorr Plus and Omron HEM-705CP II, and bidirectional conversion of blood pressure values. Objective(s): Oscillometric blood pressure (BP) measurement devices frequently replace the standard mercury sphygmomanometer. Comparisons of oscillometric devices are rare, but their agreement is important to ensure ...
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2007-09-06ZeitschriftenartikelDiscovery of herpesviruses in multi-infected primates using locked nucleic acids (LNA) and a bigenic PCR approach Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often infected with ...
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2014-12-19ZeitschriftenartikelDiscrete and overlapping functions of peptidoglycan synthases in growth, cell division and virulence of Listeria monocytogenes Upon ingestion of contaminated food, Listeria monocytogenes can cause serious infections in humans that are normally treated with β-lactam antibiotics. These target Listeria's five high molecular weight penicillin-binding ...
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2018-04-10ZeitschriftenartikelDisease detection, epidemiology and outbreak response: the digital future of public health practice Inequalities persist when it comes to the attention, resource allocation and political prioritization, and provision of appropriate, adequate, and timely health interventions to populations in need. Set against a complex ...
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2016-01-04ZeitschriftenartikelDisease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma In 1982, the term “prions” (proteinaceous infectious particles) was coined to specify a new principle of infection. A misfolded isoform of a cellular protein has been described as the causative agent of a fatal neurodegenerative ...